ESPE Abstracts

ESPE Abstracts

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hrp0092s11.3 | Recent Advances in our Understanding of Hypogonadotrophic Hypogonadism | ESPE2019

Abstract Unavailable....
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hrp0092ss1.1 | (1) | ESPE2019

E-Learning in Paediatric Endocrinology and Diabetes in Resource Limited Countries (RLC)

Boot Annemieke

The structure and design of the ESPE web portal (www.espe-elearning.org) is based on facilitating Problem-Based Learning (PBL). It consists of carefully designed problems that challenge medical students, residents, postdoc’s to use problem solving techniques, self-directed learning strategies and specialty knowledge.The ESPE e-learning web portal is an interactive learning environment for up to date topics in pediatric endocrinology and diabetes co...
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hrp0092ss1.2 | (1) | ESPE2019

E-learning ESPE interactive case

Karem Mona , Drop Stenvert

A 13 months old infant, presented with failure to thrive, untreated congenital hypothyroidism and pseudo-hypertrophy of limb muscles (i.e. Kocher-Debre-Semelaigne syndrome). The child had delayed motor and mental development. Thyroxin replacement therapy, as well as nutritional support, was initiated.Two to three weeks after treatment introduction, the motor and cognitive developments were accelerated with striking improvement as if global growth was sto...
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hrp0092mte1 | Holistic Approach to the Individual with DSD | ESPE2019

Holistic Approach to the Individual with DSD

Cools Martine

Management of DSD is a sensitive area within the field of paediatric endocrinology. On the one hand, major progress has been made in amongst others understanding the molecular genetic background and the germ cell cancer risk of certain DSD conditions. On the other hand, practices that were common in the past, such as early genital surgery have become strongly criticised and controversial nowadays, leaving clinicians as well as patients and their families with a lot of question...
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hrp0092mte2 | The Use of MRI as a Diagnostic Tool in Neuroendocrine Disorders | ESPE2019

The Interpretation of Abnormal Thyroid Function in Tests in Children and Adolescents

Moran Carla

Patients with discordant thyroid function tests (TFTs) are common clinical conundrums for the practising paediatric and adult endocrinologist. In order to avoid unnecessary investigation and treatment, a structured approach to the work up is required. During this session I will use a case based approach to review common causes of discordant TFTs, such as confounding physiological and pathophysiological factors, analytical errors, binding protein abnormalities and genetic cause...
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hrp0092mte3 | Turner syndrome - Clinical Practice Guidelines for the Care of Girls and Women with Turner Syndrome: Proceedings from the 2016 Cincinnati International - Turner Syndrome Meeting | ESPE2019

New International Guidelines on Turner Syndrome

Gravholt Claus H.

Turner syndrome (TS) affects 25-50 per 100,000 females and can involve multiple organs through all stages of life, necessitating a multidisciplinary approach to care. Numerous important advances have been noted during recent years. These advances cover all specialty fields involved in the care of girls and women with TS. This new international guideline is based on an international effort with emphasis on 1) diagnostic and genetic issues, 2) growth and development during child...
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hrp0092mte4 | Klinefelter Syndrome - when should Testosterone be Started | ESPE2019

Klinefelter Syndrome - When Should Testosterone be Started?

Rohayem Julia

Males with Klinefelter syndrome (KS) have impaired gonadal function due to sex chromosome aneuploidy (47,XXY), ultimately resulting in testicular atrophy and hypergonadotropic azoospermia, thus infertility. At what time serum testosterone (T) concentrations decline in affected individuals, thereby indicating lifelong replacement, is not predictable. An early testosterone treatment provides potential benefits with respect to body composition, neuro-muscular function and final h...
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hrp0092mte5 | Managing Endocrinopathies in McCune-Albright Syndrome | ESPE2019

Managing Endocrinopathies in McCune-Albright Syndrome

Tessaris Daniele

McCune Albright Syndrome (MAS, OMIM # 174800) is a rare congenital sporadic disorder with an estimated prevalence ranging from 1 in 1,00,000 to 1 in 100,000. MAS is caused by a post-zygotic somatic activating mutation of the GNAS1 gene resulting in an increased GSα protein signaling leading to hyperfunction of glycoprotein hormone receptors, autonomous cell proliferation, and hormonal hypersecretion. The mosaic constitutive activation of this signal transducer is clinical...
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hrp0092mte6 | Insulin Dosing for Real Meals | ESPE2019

Insulin Dosing for Real Meals

Campbell Matthew

People with type 1 diabetes are provided guidance and structured education on adjusting their mealtime bolus insulin dose based on the carbohydrate content of the meal. However, recent research in patients using continuous subcutaneous insulin infusion (CSII) and Multiple Daily Injections (MDI) has highlighted the role of dietary fat in increasing prandial insulin requirements, particularly late into the postprandial period. The average daily amount of fat consumed as part of ...
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hrp0092mte7 | Management of Graves Disease | ESPE2019

Management of Graves' Disease

Cheetham Tim , Lane Laura , Wood Claire

Managing Graves' disease (GD) should be simple. Stop the immune system from targeting the TSH receptor and the disease is cured. Unfortunately this is not yet feasible in most young people and GD is not a trivial condition for those affected. There are significant advantages and disadvantages of all current treatments with no easy way forwards for many and the family's decisions will reflect their perceptions of medical, radiation and surgical risk. The fact that two o...
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