hrp0082p2-d2-425 | Growth Hormone (1) | ESPE2014

Electronic Devices and Single-Dose Dispensing Systems GH are the Most Efficient and Less Loss of Drug

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Elizalde Miriam Miriam , Lorente-Blazquez Isabel , Minguez Cristina , Martinez-Martinez Carlos

Background: Several pharmaceutical formulations marketed GHRH, were being restricted in their choice occasions. Three display groups: single-dose, pre-filled pens/vials and electronic devices, self-injection systems. The choice may contribute to a greater or lesser adherence and a difference in the final cost of treatment (drug loss), attributable to the device itself or presentation. Presentations that require reconstitution device load, partial doses or stop in Pen contribut...

hrp0082p2-d3-447 | Growth Hormone (2) | ESPE2014

Efficacy, Adherence, and Cost Study According to Pathology and Treatment Devices in Children Treated with GHRH

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Elizalde Miriam Miriam , Lorente-Blazquez Isabel , Minguez Cristina , Martinez-Martinez Carlos

Background: Currently there are three distinct groups of GH devices: single dose (JM), preloaded pen/vial (VM) systems and electronic devices (DE) autoinjector systems. The choice could determine a greater or lesser adherence and thus influence the final treatment efficacy.Objective: Comparison of the therapeutic efficacy as measured by growth rate (VC), IGF1 as a function of various clinical variables, indicating GH and device used.<p class="abstext...

hrp0084p3-1040 | Growth | ESPE2015

Psychomotor Development in Children Born Small for Gestational Age During Early Infancy

Puga Beatriz , Olivan Maria J , Galve Zenaida , Rite Segundo , de Arriba Antonio , Ferrer Marta , Labarta Jose Ignacio , Ferrandez Angel

Background: Neurocognitive retardation is one of the most important consequences that small for gestational age (SGA) children may suffer although conflicting results have been published.Objective and hypotheses: The aim of this study was to study psychomotor development (PD) in children born SGA during the first two years of life in order to identify children at risk as early as possible.Method: 108 cases borh SGA have been studie...

hrp0094p2-403 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2021

Surgical aspects of the multicentric and interdisciplinary study in minors with different sexual development

Nerea Gonzalez-Temprano , Villalón Flor , Cancela Vanesa , Nuñez Francisco Javier , Hernandez Jone Miren , Diez-Lopez Ignacio

After the evident socio-health transformation when facing intersexualities / entities with different sexual development (DSD), we wonder if clinical-care assistance has improved. Material and method Descriptive multicenter study by means of a retrospective review (2006-2019) of patients with a diagnosis of DSD in pediatric age. Interdisciplinary assessment through satisfaction surveys to families / patients.Results: 67 patients were included. 27% were op...

hrp0094p2-218 | Fat, metabolism and obesity | ESPE2021

Impact of overweight and obesity in pediatrics. Metabolic syndrome and its components

San Martin Amaya , Vilella Leyre , Garcia Casales Zurine , Calvo Ariadne , Rocha C , Sarasua Miranda Ainhoa , Diez-Lopez Ignacio ,

The current lifestyle, with a diet increasingly removed from the Mediterranean diet, together with the habitual sedentary lifestyle, is associated with many of the so-called non-communicable diseases, such as the metabolic syndrome. Every day these pathologies are more frequent in pediatrics, so this study has tried to establish the prevalence of metabolic syndrome and its components in overweight and obese children and assess its impact. METHODS A descriptive study has been c...

hrp0095p2-125 | Fat, Metabolism and Obesity | ESPE2022

Effects of confinement due to COVID-19 in the child population of Álava on vitamin D status, weight and body composition

and body composition weight , Aguirre-Lopez Leixure , Puy Portillo-Baquedano Mari , Fernandez-Quintela Alfredo , Leniz-Rodríguez Asier , Diez-Lopez Ignacio

The coronavirus disease (COVID-19) pandemic brought with it a state of alarm as of March 14, 2020, which implied a restriction on the mobility of the general population and home confinement. One of the main concerns raised by isolation was the substantial reduction in energy expenditure due to children spending more time sitting or participating in activities that involve very low rates of energy expenditure, such as watching television, managing the different networks social ...

hrp0092p2-128 | Fat, Metabolism and Obesity | ESPE2019

Is one year of Diet and Physical Activity Program for Obese Children Enough to Revert the Metabolic Disorders?

Garcia Cuartero Beatriz , Garcia Lacalle Concepcion , Sanchez Escudero Veronica , Sanchez Salado Laura , Martin Garcia Maria , Ara Royo Ignacio , Gonzalez Vergaz Amparo

Objetives: To analyse clinical and laboratory characteristics of an obese pediatric population.To assess their response to specific program consisting in modification of their nutritional habits and physical activity .Material and Methods: Obese patients completed a year of group therapy with nutritional education and physical activity. We analysed at the beggining and after a year anthropometry an...

hrp0092p3-320 | Late Breaking Abstracts | ESPE2019

EpiPEG-PreMeb Study: Chemerina Plasmatic and Metabolic Syndrome Relation at SGA Childrens

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Leniz Asier , Fernandez-Quintela Alfredo , Portillo Maria Puy , Macarulla-Arenaza Maria Teresa , Lorente-Blazquez Isabel

The objective of this study has been the analysis of plasma chemistry in a group of children born SGA at the University Hospital of Álava- Txagorritxu and biochemical parameters related to the metabolic syndrome.Material and Methods: In a cohort of 27 subjects sub (13 boys and 14 girls) from the epiPEG-PreMeb study, a blood sample at 3, 12 and 24 months of life it was extracted. Biochemical parameters s and measured by automated and...

hrp0089p3-p240 | Growth &amp; Syndromes P3 | ESPE2018

The Expression of Cytokines in SGA Children Throughout Lactation Allows to Characterize Early the Type of Cath-up

Diez-Lopez Ignacio , Sarasua Ainhoa , delHoyo Marta , Lorente Isabel , Segura Raquel Gomez de , Picon Minerva , Leniz Asier , Fernandez Alfredo , Puy-Portillo Maria

Up to 50% of children born SGA at 2 years have not made a correct catch up (by excess or defect), with repercussions on size, metabolic and cardiovascular alterations, DM, etc. The Project has developed a prospective cohort of SGA and seeks to study phenotypic, BQ and genetic differences that explain their different behavior.Material and methods: We study live births of single pregnancies in our Hospital during 2012–2014, and are classified accordin...

hrp0086p1-p639 | Growth P1 | ESPE2016

Spanish ECOS Study Analysis: Socioeconomic Data, Adherence and Growth Outcomes with Case Studies

Rodriguez-Arnao Maria , Sanchez Amparo Rodriguez , Lopez Ignacio Diez , Fernandez Joaquin Ramirez , de la Vega Jose Bermudez , Ballano Virginia , Nieto Jenny Alvarez , Koledova Ekaterina

Background: The ECOS observational study in Spain (NCT01376921) aims to evaluate adherence to r-hGH therapy prescribed via the easypod™ electromechanical auto-injector device and to analyse factors that may influence adherence in paediatric patients. Easypod™ administers pre-set doses of Saizen® r-hGH and stores accurate records of each dose and injection taken, which can then be shared with the HCP for evaluation of the patient’s adherence.<...