hrp0082p1-d1-58 | Diabetes | ESPE2014
, Blouin Jean-Louis
, Bevillard Jeremy
, Santoni Federico
, Schwitzgebel Valerie
Background: Neonatal diabetes mellitus is defined by severe hyperglycemia appearing before 6 months of age. It occurs in about one in 200 000 live births and most cases are known to be of monogenic origin. Classical autoimmune type 1 diabetes mellitus (DM) is exceptional in this age group.Objective and hypotheses: Recently non-HLA type 1 DM susceptibility genes, such as IL18RAP, influencing the rate of progression to diabetes among children with...