hrp0092p1-131 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Is there the Relationship Between Anxiety and Depression Level and Clinical Presentation of Polycystic Ovary Syndrome in Adolescent Girls?

Zachurzok Agnieszka , Pasztak-Opilka Agnieszka , Malecka-Tendera Ewa

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder of the young women, and it could influence both physical and psychological wellbeing. As a consequence of obesity and hirsutism lower sexual attractiveness, higher emotional distress as well as higher depression score is frequently observed.Study Objective was to evaluate anxiety and depression score as well as the body esteem and stress perception ...

hrp0084p2-409 | GH & IGF | ESPE2015

The Influence of GH Therapy on Chemerin Concentration, Body Mass and Selected Parameters of Carbohydrate Metabolism in Prepubertal Non-Obese Children with GH Deficiency

Rudzka-Kocjan Agnieszka , Szalecki Mieczyslaw

Background: Chemerin is an adipocytokine which plays a great role in metabolism of carbohydrates. Chemerin concentration correlates positively with body mass (BM). GH deficiency (GHD) is associated with excess of abdominal fat tissue also in patients with normal BMI.Objective and hypotheses: To estimate the chemerin concentration and its correlation with BM and carbohydrate metabolism in non-obese, prepubertal children with isolated GHD before (GHD untre...

hrp0084p2-411 | GH & IGF | ESPE2015

Estimation of Adipsin, Omentin and Vaspin Concentration in Prepubertal Children with GH Deficiency before and after 6 Months of GH Treatment

Rudzka-Kocjan Agnieszka , Szalecki Mieczyslaw

Background: GH deficiency (GHD) is usually associated with excess of abdominal fat tissue and increased risk of developing cardiovascular diseases. Adipose tissue produces different adipocytokines that could explain the relationship between excess of fat tissue and increased metabolic risk. Adipsin, omentin and vaspin are adipocytokines which are still not well examined.Objective and hypotheses: To estimate the effect of 6 months GH therapy on serum conc...

hrp0089p2-p350 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P2 | ESPE2018

Psychological Gender Features and Social Abilities and in Adolescent Girls – Influence of Obesity and Hyperandrogenism

Zachurzok Agnieszka , Pasztak-Opilka Agnieszka , Forys-Dworniczak Elzbieta , Drosdzol-Cop Agnieszka , Gawlik Aneta , Malecka-Tendera Ewa

Background: Both, obesity and hyperandrogenism are the conditions that can influence many different health domains, also may affect the mental and social wellbeing components of subject’s life.Study objective: To evaluate whether body weight status and clinical hyperandrogenism may influence social competencies and psychological gender features in adolescent girls.Design & participants: In 104 adolescent girls clinical eva...

hrp0092t5 | Top 20 Poster | ESPE2019

Evaluation of Toll-like Receptor 2 Expression on T Lymphocytes in Patients with Graves' Disease in Relation to the Clinical Parameters

Klatka Maria , Grywalska Ewelina , Polak Agnieszka

Introduction: Graves'disease (GD) is a polygenic and multifactorial disease.The innate immune system is a complex network of structured cells and proteins, including the Toll-like receptors (TLRs), which are also expressed on the cells of the adaptive immune system.The aim was to assess the relationship between the expression of TLR-2 on the surface of T CD4+ and CD8+ lymphocytes in pat...

hrp0092p3-66 | Diabetes and Insulin | ESPE2019

Familial Hypercholesterolaemia as a Cause of Dyslipidemia in Patient with Type 1 Diabetes

Brandt-Varma Agnieszka , Hennig Matylda , Mysliwiec Malgorzata

Introduction: Diabetes type 1 (DM1) in children can result in lipid disorders due to insulin deficiency. Familial hypercholesterolaemia (FH) is a very common monogenic disorder with occurrence of 1:250 and it may lead to development of cardiovascular disease (CAD) in a very young age.Case report: Female patient with diabetes diagnosed at the age of 5, was referred to joint diabetes and lipid clinic due to high levels of ...

hrp0086p1-p256 | Diabetes P1 | ESPE2016

The Incidence of Type 1 Diabetes in the Pediatric Population in Pomeranian Region in Poland

Brandt Agnieszka , Derkowska Ilona , Mysliwiec Malgorzata

Background: It is observed from nearly 50 years that the incidence of diabetes worldwide is increasing. Also the incidence of type 1 diabetes, which is most common in paediatric population, rises across Europe.Objective and hypotheses: The aim of the study was to analyze the incidence of type 1 diabetes in Poland in Pomeranian province in the years 2005, 2010 and 2015. The hypothesis was an increased incidence of type 1 diabetes.Me...

hrp0086p2-p651 | Growth P2 | ESPE2016

Estimation of FGF21 Concentration in Prepubertal Children with Growth Hormone Deficiency before and after 6 Months of Growth Hormone Treatment

Rudzka-Kocjan Agnieszka , Szalecki Mieczyslaw , Malinowska Anna

Background: Fibroblast growth factor 21 (FGF21) is a metabolic and growth regulator. The growth-promoting effect of GH in children with GH deficiency (GHD) depends on many factors. FGF21 concentration in and its interaction with growth deficiency and growth response to GH therapy in GHD was not examined.Objective and hypotheses: To estimate the FGF21 concentration and its correlation with degree of growth deficiency and growth response in non-obese, prep...

hrp0086p2-p766 | Pituitary and Neuroendocrinology P2 | ESPE2016

Congenital Craniopharyngioma: Report of Two Cases

Bogusz Agnieszka , Moszczynska Elzbieta , Szalecki Mieczyslaw

Introduction: Craniopharyngiomas are slow growing epithelial tumors located in the sellar or suprasellar region of the brain. Adamantinomatous subtype affects mainly children and accounts for 5–10% of all intracranial paediatric tumors. Diagnosed antenatal and neonatal craniopharyngiomas are very seldom, about 40 such cases have been detected to date. They are characterised by large size, progressive hydrocephalus and a poor prognosis.Aim: The aim o...

hrp0084p3-1074 | Hypo | ESPE2015

Congenital Hyperinsulinism in Siblings: Case Report

Brandt Agnieszka , Buraczewska Marta , Mysliwiec Malgorzata

Background: Congenital hyperinsulinism (CHI) is the most common cause of hypoglycemia in childhood, and diagnosis and treatment of CHI is one of the most difficult aspects of modern endocrinology and diabetology. In half of infants suffering from congenital hyperinsulinism, which may require resection of pancreatic, potentially curable focal form can be found. Recently introduced diagnostic imaging using 18F-DOPA-PET allows for differentiation as a diffuse and focal...