hrp0082p1-d1-64 | Diabetes | ESPE2014

Biomarkers of Subclinical Inflammation in an Infant–Juvenile Population with Type 1 Diabetes

Bazan Maria , Casella Sofia , Lopez Santiago , Carrizo Teresita , Velarde Maria , Diaz Elba , Abregu Adela

Background: Diabetes is associated with increased risk of vascular disease. In children and adolescents with type 1 diabetes (T1D), clinical manifestations of vascular complications are infrequent; however, a pro-inflammatory state and endothelial disturbance could appear early. A subclinical inflammation state result in increased plasma levels of adhesion molecules, inflammatory cytokines as tumor necrosis factor alpha (TNF╬▒), and acute phase proteins as C-reactive prote...