hrp0082p3-d3-945 | Puberty and Neuroendocrinology (1) | ESPE2014

Precipitated Puberty: Correlations with Embarrassed Ovarian Function

Circo Eduard

Scope: The assessment of the functional ovarian maturity in a group of girls with precipitated puberty.Method: Ovarian function was assessed in a group of girls with puberty precipitated (77 – group 1) compared with a group of girls with normal puberty (59 – group 2) according to development criteria accepted by the population of Romania. They calculated the incidence of menstrual disorders, changes in menstrual flow, presence of dysmenorrhoea ...

hrp0089p3-p373 | Thyroid P3 | ESPE2018

Hypovitaminosis D and Chronic Autoimmune Thyroiditis Mammary Echostructural Involvements in Puberty

Ibadula Seila , Circo Eduard

Introduction: Benign breast pathology has a frequent onset during puberty-adolescence.Objectives: Differential evaluation of breast echostructure in puberty stage III/V, on Tanner scale, depending on the presence of thyroid autoimmunity and hypovitaminosis D.Method: Assessment of BIRADS score from 2 to 4 in three groups of girls associating premenstrual mastodynia: Group 1 - including patients with chronic autoimmune thyroiditis an...

hrp0092p2-207 | Multisystem Endocrine Disorders | ESPE2019

Functional Ovarian and Thyroid Disturbances in a Group of Adolescents with Insulin Dependent Diabetes Mellitus and Vitamin D Deficiency

Seila Ibadula , Scrinic Olesea , Circo Eduard

Aim of the study: Assessment of the incidence of ovarian functional disorders correlated with thyroid disorders appreciated clinically, functional, and echostructural in a group of diabetic female teenagers according to 25-(OH)- vitamin D serum levels.Method: A group of 31 patients with diabetes mellitus and vitamin D deficiency (mean age 16.3 ± 1.3) was studied compared to a control group (43 teenagers) with diabet...

hrp0089p3-p372 | Thyroid P3 | ESPE2018

Dento - Maxillary and Periodontal Changes in Puberty/Adolescence in Subclinical Hypothyroidism of Autoimmune Cause

Circo Eduard , Gosu Cristina , Ibadula Seila , Circo Razvan

Introduction: The development of the dentomaxillary system in children involves a normal thyroid function. Juvenile hypothyroidism has different complications depending on the congenital or acquired nature of it.Objective: To identify periodontal changes under the conditions of chronic autoimmune thyroiditis and subclinical hypothyroidism.Material and method: The study group comprised 24 young patients, 15 girls and 9 boys (15.2&#1...

hrp0089p2-p075 | Diabetes & Insulin P2 | ESPE2018

Type 5 Monogenic Diabetes: Reportof 7 Cases

Eduard Mogas , Rosa Pacheco , Diego Yeste , Ariadna Campos , Luis Castano , Maria Clemente

Introduction: Type 5 monogenic diabetes is an autosomal dominant disease due to a mutation in HNF1beta gene. This gene is expressed predominantly in kidney and pancreas, thus clinical manifestations are characterised by renal abnormalities and diabetes.Objectives: To review the clinical characteristics of patients who were diagnosed with type 5 monogenic diabetes in the Pediatric Endocrinology Unit of a tertiary referral hospital.<p class="a...

hrp0089p3-p184 | Fetal, Neonatal Endocrinology and Metabolism P3 | ESPE2018

Mutation in UCP2 Gene: A Rare Cause of Hyperinsulinemic Hypoglycaemia Syndrome in a Small-for-Gestational Age Newborn

Clemente Maria , Yesquen Pamela , Campos Ariadna , Mogas Eduard , Fernandez Monica , Yeste Diego

Hyperinsulinism is a common cause of severe and persistent hypoglycaemia during the neonatal period. Eleven genes have been identified that lead to unregulated insulin secretion and hyperinsulinemic hypoglycaemia (HH). Inactivating mutations in UCP2 gene have been described in a very small number of patients with HH. UCP2 protein is an inner mitochondrial carrier protein and its loss of function causes enhanced glucose oxidation and increased intracellular ATP synthes...

hrp0089p2-p215 | GH &amp; IGFs P2 | ESPE2018

Systematic Prospective Study of Eye Funduscopy Before and After Starting Treatment with Growth Hormone in 290 Patients

Eduard Mogas , Nieves Martin , Diego Yeste , Luis Castano , Maria Clemente , Ariadna Campos , Antonio Carrascosa

Introduction: Idiopathic intracranial hypertension (IIH) is a rare entity in childhood. It is characterized by signs and symptoms of increased intracranial pressure with normal neurological examination (except for possible paresis of the sixth cranial nerve), cerebrospinal fluid study and neuroimaging. The association between HII and treatment with growth hormone (GH) was first described in 1993 by the Food and Drug Administration and it has later been demonstrated. Incidence ...

hrp0082p2-d3-504 | Perinatal and Neonatal Endocrinology | ESPE2014

Vitamin D Deficiency as the Primary Cause of Neonatal Hypocalcemia in a Tertiary Hospital

Campos-Martorell Ariadna , Narvaez Karla , Clemente Maria , Yeste Diego , Mogas Eduard , Gerones Laura , Carrascosa Antonio

Background: Hypocalcemia is a common metabolic disorder in the neonatal period and may involve life-threatening situations. The aim is to analyze the main causes of hypocalcemia and its management.Objective and hypotheses: The aim is to analyze the main causes of hypocalcemia and its management.Method: Retrospective descriptive study by reviewing reports of 75 patients diagnosed of neonatal hypocalcemia (total Ca <7.6 mg/dl and...

hrp0082p3-d1-885 | Perinatal and Neonatal Endocrinology | ESPE2014

Neonatal Seizures Neonatal due to Hypocalcemia Secondary to Maternal Vitamin D Deficiency

Campos-Martorell Ariadna , Narvaez Karla , Clemente Maria , Yeste Diego , Mogas Eduard , Gerones Laura , Carrascosa Antonio

Background: Vitamin D is an essential hormone in the homeostasis of calcium. Its main source is sun exposure. Changes in lifestyle and migratory movements have favored the reappearance of vitamin deficiency in our country.Method: We present three cases of newborn with hypocalcemic seizures, secondary to maternal vitamin D deficiency. Mother’s origin was North Africa.Results: Case 1: 7 days old male brought for several episodes...

hrp0094p2-129 | Diabetes and insulin | ESPE2021

Evaluation of continuous glucose monitoring for the diagnosis of cystic fibrosis related diabetes (CFRD). A prospective and longitudinal study

Yesquen Pamela , Campos Ariadna , Mogas Eduard , Gartner Silvia , Yeste Diego , Clemente Maria ,

Introduction: Continuous-glucose monitoring (CGM) is becoming a useful tool to evaluate glucose profiles in real-life conditions and to detect glucose abnormalities undetected by OGTT in CF patients.Objectives: • Evaluation of OGTT and CGM results longitudinally • Evaluation of BMI z-score and %FEV1 changes in relation to OGTT and CGM results. • Analysis of 6 proposed criteria to classify glucose abnormali...