hrp0084p3-1233 | Turner | ESPE2015

Growth Curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group

Darendeliler Feyza , Bereket Abdullah , Bas Firdevs , Bundak Ruveyde , Sari Erkan , Aydin Banu K , Darcan Sukran , Dundar Bumin , Buyukinan Muammer , Kara Cengiz , Mazicioglu Mumtaz M , Adal Erdal , Akinci Aysehan , Atabek Mehmet E , Demirel Fatma , Celik Nurullah , Ozkan Behzat , Simsek Enver , Cinaz Peyami , Group Turner Syndrome Study

Background: Children with Turner syndrome (TS) have a specific growth pattern that is quite different from that of healthy children. Many countries have population specific growth charts for TS.Objective and hypotheses: Considering national and ethnic differences, we undertook this multicentered collaborative study to construct growth charts and reference values for height, weight, and BMI from birth to adulthood for spontaneous growth of Turkish girls w...

hrp0084p3-1243 | Turner | ESPE2015

Anthropometric Findings from Birth to Adulthood in Turkish Girls with Turner Syndrome and Association with Karyotpye Distribution

Sari Erkan , Bereket Abdullah , Yesilkaya Ediz , Bas Firdevs , Bundak Ruveyde , Aydin Banu K , Darcan Sukran , Dundar Bumin , Buyukinan Muammer , Kara Cengiz , Adal Erdal , Akinci Aysehan , Atabek Mehmet E , Demirel Fatma , Celik Nurullah , Ozkan Behzat , Ozhan Bayram , Orbak Zerrin , Ercan Oya , Study Group Turner Syndrome

Background: Turner syndrome (TS) can manifest with various clinical features depending on the karyotype and the genetic background of affected subjects.Objective and hypotheses: The aim of this study was to evaluate growth parameters from birth to adulthood in girls with TS in a cross-sectional study.Method: A total of 842 patients, with an age of diagnosis ranging from birth to 18 years followed-up between 1984 and 2014, from 35 d...

hrp0094p2-88 | Bone, growth plate and mineral metabolism | ESPE2021

Two sibling cases with heterozygous calcium sensing receptor (CaSR) gene mutation

Kurnaz Erdal , Savaş-Erdeve Şenay , Demirel Nihal , Aycan Zehra , Cetinkaya Semra ,

Background: Heterozygous inactivating mutations in the calcium sensing receptor (CaSR) gene cause mild hypercalcemia, normal to slightly elevated parathormone (PTH) levels and may vary from an asymptomatic clinical picture to a mild course. This clinical picture is also called familial hypercalcemic hypocalciuria. In this study, it is aimed to present two sibling cases due to CaSR mutation with interesting features.Case...

hrp0082p3-d3-809 | Gonads and Gynaecology | ESPE2014

Three Siblings with Gonadal Dysgenesis

Dursun Fatma , Kirmizibekmez Heves

Background: Gonadal dysgenesis in female is defined as absent or insufficient development of ovaries. The patient with gonadal dysgenesis presents with primary amenorrhea and lack of development of secondary sexual characteristics. The patterns of inheritance is thought to be autosomal recessive.Case 1: A fourteen and half year-old-girl, presented with delayed puberty. She was born from consanguineous parents. Pelvic ultrasonography revealed streak ovari...

hrp0089p3-p220 | Growth & Syndromes P3 | ESPE2018

Effect of Sickle Cell Disease on Growth and Puberty

Omar Anjumanara , Abdallah Fatma , Mutai Beatrice

Background: Research has shown that some of the endocrine disorders in patients with sickle cell disease include delayed growth and pubertal development. No study has been done in Kenya to investigate whether this applies for the local children with sickle cell anaemia.Objective: To describe growth and pubertal development in children and adolescents with Sickle cell disease.Methodology: This was a cross-sectional descriptive study...

hrp0086p2-p74 | Adrenal P2 | ESPE2016

Cholestasis and Hypercalcemia Secondary to Panhypopituitarism in a Newborn

Dursun Fatma , Gerenli Nelgin , Kirmizibekmez Heves

Cholestatic hepatitis and hypercalcemia are rare features of hypopituitarism in the newborn. So diagnosis of hypopituitarism is frequently delayed. Herein, we report a newborn that was investigated for cortisol deficiency and other pituitary hormone deficiencies and diagnosed with panhypopituitarism upon detection of cholestasis after referral to the endocrinology department for hypercalcemia, a very rare sign of cortisol deficiency. It is unclear which hormone causes cholesta...

hrp0084p2-349 | Fat | ESPE2015

Subepicardial Adipose Tissue and Carotid Intima–Media Thickness in Obese Children and Their Relationship Between Metabolic and Clinical Parameters

Boyraz Mehmet , Uzun Fatma , Eminoglu Sancar

Introduction and objective: Atherosclerosis is one of the most important causes of obesity-related diseases. The clinical symptoms usually begin in adulthood, but the pathological changes in vascular structure could be observed in a much earlier period. Carotid intima–media thickness (cIMK) which is one of the noninvasive marker of early atherosclerotic changes, has been shown to be significantly increased in obese children. Subepicardial adipose tissue (SAT) is a compone...

hrp0084p3-825 | Endocrine Oncology | ESPE2015

GH and Prolactin Secreting Adenoma in an Adolescent Boy

Dursun Fatma , Kirmizibekmez Heves , Dagcinar Adnan

Background: Pituitary gigantism is a rare disorder. Paediatric endocrinologists may see at most one or two patients during their careers. In one large series of 2367 children and adolescents with pituitary adenomas, only 15 (0.6%) had pituitary gigantism. Much of our understanding is derived from isolated case reports and extrapolation from the adult literature. No sex predilection is known. Gigantism may occur at any age, and has been observed as early as the first 6–9 m...

hrp0095p1-361 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Blue Light Exposure and Exposure Duration Effects on Rats' Puberty Process

Kılınç Uğurlu Aylin , Bideci Aysun , Mürşide Demirel Ayşe , Take Kaplanoğlu Gülnur , Dayanır Duygu , Gülbahar Özlem , Saadet Deveci Bulut Tuba , Döğer Esra , Orhun Çamurdan M.

Introduction: In the last 10 years, blue light (BL) sources such as tablets and phones has increased in every age group. Especially due to the Covid-19 pandemic, screen exposure has also increased in childhood. However, the effects of BL exposure in the puberty process aren’t clear. We aimed to examine the effect of BL exposure and exposure time on pubertyMethods: Immature eighteen 21-day-old female Sprague Dawley ...

hrp0092lb-8 | Late Breaking Posters | ESPE2019

Detection of Cardiomyopathy in Egyptian Children and Adolescents with Longstanding Obesity Using Cardiac Marker NT-pro PNB and Speckled Tracking Echocardiography

Hafez Mona , Musa Noha , Fakhry Antoine , ELMougy Fatma , ELShennawy Hala

Introduction: Obesity is considered a major risk factor for developing cardiovascular morbidity and mortality. Obesity affects the structure and function of the heart mainly by causing increased blood volume, elevated cardiac output, left ventricular (LV) hypertrophy, and LV diastolic dysfunction. All of which can play a role in causing heart failure.Objective: This cross-sectional study aimed to evaluate the effect of l...