hrp0092p1-119 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Menarche and its Relation to the Pubertal Growth Spurt

Gardstedt Jenni , Niklasson Aimon , Aronson Stefan , Albertsson-Wikland Kerstin , Holmgren Anton

Background: Both timing of menarche and growth patterns have changed with time (secular changes), highlighting the need of updated knowledge in this topic1. Questions how growth is related to menarche are common in pediatric/pediatric endocrine outpatient clinics. The QEPS-growth model makes it possible to conduct detailed analyses of pubertal growth2.Objective: To investigate the relationship betwe...

hrp0089p1-p169 | Growth & Syndromes P1 | ESPE2018

A Novel Type of Pubertal Height, Weight, and BMI Reference, Aligned for Onset of Puberty

Albertsson-Wikland Kerstin , Niklasson Aimon , Gelander Lars , Holmgren Anton , Aronson Stefan , Sjoberg Agneta , Lissner Lauren

Context: Specific references for height, weight and BMI that consider the maturation tempo for onset of puberty are lacking worldwide.Aim: To fill the gap, by developing specific pubertal references for heightSDS, weightSDS and BMISDS, all aligned for the individual onset of puberty.Method: Reference population: a subgroup of GrowUp1990Gothenburg cohort of 1572 (763 girls) health...

hrp0089p1-p117 | Fat, Metabolism and Obesity P1 | ESPE2018

The More Obese – The Less Pubertal Height Gain

Holmgren Anton , Niklasson Aimon , Martinez-Villanueva Julian , Martos-Moreno Gabriel A , Argente Jesus , Albertsson-Wikland Kerstin

Background: In a population of a community-based setting (BMISDS range −3.5 to +4.1), there is a negative linear correlation between childhood BMISDS and pubertal height gain, together with earlier onset of pubertal growth with higher BMISDS for both sexes (1).Objective: To investigate the impact of BMI in childhood on the pubertal pattern of growth for obese children in a clinical setting.Met...

hrp0094p1-168 | Growth B | ESPE2021

Mother’s smoking during pregnancy influence intrauterine and postnatal growth - the GrowUp 1990 Gothenburg cohort population

Holmgren Anton , Niklasson Aimon , Aronson A. Stefan , Albertsson-Wikland Kerstin ,

Background/Objective: Smoking during pregnancy is known to influence prenatal/postnatal growth of the offspring. We investigated the impact of smoking in the Swedish reference population for new reference for height, weight and BMI, the GrowUp1990Gothenburg cohort.Material/Methods: The study was based on 1907 healthy children (918girls/989boys) born at term in Sweden with Nordic parents and longitudinal growth measurements. 155girls/180b...

hrp0092rfc12.6 | Growth and Syndromes (to include Turner syndrome) | ESPE2019

Exploring the Usefullness of a New Type of Pubertal Heigh Reference Based on Growth Aligned or Onset of Pubertal Growth

Albertsson Wikland Kerstin , Niklasson Aimon , Holmgren Anton , Gelander Lars , Nierop Andreas

Background: Height references have been available for decades, although only related to chronological age and not considering the broad individual variation in the timing and tempo of pubertal maturation and growth. Therefore, growth references and growth charts for the adolescent period have been of limited usefulness both for monitoring growth in individuals and for research. To fill this gap, we recently developed a new type of height reference based on gro...

hrp0092p1-250 | Pituitary, Neuroendocrinology and Puberty (1) | ESPE2019

Correlation Between Pubertal Growth and Testicular Volume in Boys –a Longitudinal Study

Holmgren Anton , Niklasson Aimon , Aronson A. Stefan , Nierop Andreas F.M. , Albertsson-Wikland Kerstin

Background: Few studies have investigated how the pubertal increase in testicular volume (TV) is related to pubertal growth spurt in a longitudinal setting. Increased TV, indicating onset of puberty in boys, mirrors the enhanced testosterone production in the testicles which also give rise to the pubertal growth spurt. The QEPS-growth model makes it possible to conduct detailed analyses of pubertal growth and separate total growth into specific pubertal (P-fun...

hrp0089p1-p170 | Growth & Syndromes P1 | ESPE2018

Evaluating Cut-offs for Automatic Growth Screening in Swedish Children – Using the Finnish Growth Monitoring Algorithm

Gelander Lars , Niklasson Aimon , Holmgren Anton , Saari Antti , Dunkel Leo , Albertsson-Wikland Kerstin

Background: Growth charts provide excellent help to the pediatric team in identifying abnormal growth patterns. However, the evaluation is highly dependent on the skills of the clinician. A computerized automatic screening system will add quality and patient safety in finding children with disorders affecting growth. Such screening system has been developed and tested in Finland and resulted in earlier detection of growth disorders1-3.Aim: To ...

hrp0082p2-d1-453 | Growth | ESPE2014

New Reference for Height in Swedish Boys and Girls

Albertsson-Wikland Kerstin , Niklasson Aimon , Gelander Lars , Holmgren Anton , Nierop Andreas F M

Background: The actual Swedish growth references are based on a cohort born 1974.Objective and hypotheses: Due to secular changes there is need for new height references.Method: Material: Height measurements from birth to adult height (AH) in a cohort of healthy, Nordic and born full term 1990, 20.796 from 1647 boys, 19.202 from 1501 girls were used (ALL) and compared to both a subgroup with puberty close to mean (PHV &#17...

hrp0094p1-162 | Growth B | ESPE2021

Evaluation of growth patterns from the Edinburgh and Gothenburg cohorts by the QEPS model

Holmgren Anton , Niklasson Aimon , Nierop Andreas F.M , Butler Gary , Albertsson-Wikland Kerstin ,

Background: The QEPS-growth-model, developed and validated in GrowUpGothenburg cohorts, used for developing growth references and investigating healthy/pathological growth, lacks external validation from other longitudinal cohorts of healthy individuals.Objective: To investigate if the QEPS-model fits the longitudinal Edinburgh growth study of another design than GrowUpGothenburg cohorts. To compare growth patterns in tw...

hrp0094p2-354 | Pituitary, neuroendocrinology and puberty | ESPE2021

Relation between specific pubertal growth and breast maturation - a longitudinal study in healthy girls

Bergendahl Sophie , Niklasson Aimon , Stefan Aronson A. , Nierop Andreas F.M , Albertsson-Wikland Kerstin , Holmgren Anton ,

Background: Few studies have investigated in detail how the pubertal breast maturation in girls is related to the pubertal growth spurt in a longitudinal setting. The golden standard for assessment of secondary sex characteristics for girls includes breast development (B1-B5)1. The different maturation stages follow the increasing estradiol production from the ovaries also giving rise to the pubertal growth spurt. The QEPS-growth model makes it poss...