hrp0086rfc5.8 | Management of Disorders of Insulin Secretion | ESPE2016

Stress Management and Health Promotion through Family Intervention Improves Metabolic Control in Children and Adolescents with Type 1 Diabetes

Panayi Laura , Kanaka-Gantenbein Christina , Darviri Christina , Chrousos George P.

Background: Optimal glycemic control in children and adolescents with type 1 diabetes mellitus (T1DM) is often hampered owing to psychologic maladjustment of both patients and their parents. Accumulating evidence suggests that hyperglycemia may be associated with prolonged activation of the stress system.Objective and hypotheses: To pilot test a 12-week intervention program including psychoeducation about stress, healthy lifestyle, diaphragmatic breathin...

hrp0092p1-242 | Multisystem Endocrine Disorders | ESPE2019

Basal Metabolic Rate in Polycystic Ovary Syndrome: A Meta-Analysis

Geronikolou Styliani , Kanaka-Gantenbein Christina , Bacopoulou Flora

Background: While polycystic ovary syndrome (PCOS) is implicated with insulin resistance and obesity, little is known about the abnormal energy imbalance contribution to the disease. Basal metabolic rate (BMR) represents the energy expenditure by a normal subject at rest, remote from eating, in a thermally neutral environment, reflecting the 50–70% of total daily metabolism. The relevant literature is limited with conflicting results- worth meta-analy...

hrp0092p2-204 | Multisystem Endocrine Disorders | ESPE2019

Electromagnetic Fields Exposure in Adolescents: A Survey in 11-14 y Old Greek Students

Geronikolou Styliani , Chrousos George , Kanaka-Gantenbein Christina

Background: Electromagnetic field (EMF) exposure has been considered a potential environmental toxicant, which may influence endocrine and other functions, while population awareness remains limited. In an earlier study, we demonstrated that EMF alters the hypothalamic-pituitary-adrenal axis in children using a 3G mobile telephone.Aim: To screen and compare the motives, knowledge and status of electromagnetic field expos...

hrp0089p3-p279 | Multisystem Endocrine Disorders P3 | ESPE2018

Near Electromagnetic Fields – Induced Syndrome: Unsuspected and Newly Recognised

Geronikolou Styliani , Chrousos George , Kanaka-Gantenbein Christina

This present study investigates the impact of a common environmental hazard, the radiofrequency fields (RF), such as those regarding cell phones, cell phone base stations, wi-fi, portable phones (DECT), etc., as close to the body sources of exposure, on endocrine function. This is of importance, particularly for developing children, that have been and are exposed to this potential hazard. We performed analyses on endocrine assessments regarding stress, thyroid hand reproductiv...

hrp0089p3-p376 | Thyroid P3 | ESPE2018

An Impressive Recovery of Arrested Growth and Puberty in a 13 Year Old Boy after Being Treated for Simultaneously Diagnosed Severe Hypothyroidism and Coeliac Disease

Fafoula Olga , Panagouli Eleni , Panagiotakou Argyro , Mpeni Maria , Georgila Chrisitina , Korovessi Paraskevi , Kostaridou Stauroula

Background: Individuals with celiac disease are more likely to develop autoimmune thyroid disease compare to the general population and vice versa. Undiagnosed in childhood and adolescence, both diseases compromise final height. Clinical experience shows that near complete catch-up growth is possible in infants and young children, but not in children near or in puberty.Objectives: To report on the impressive acceleration of arrested growth in a 13 year o...

hrp0086wg3.1 | ESPE Turner Syndrome Working Group (TS) | ESPE2016

Spontaneous Fertility and Pregnancy Outcomes in Turner Syndrome

Christin-Maitre Sophie

Background: Turner syndrome (TS) occurs in 1/2000 newborn girls. Primary ovarian insufficiency (POI), due to an increased follicular apoptosis, is a classic feature of TS. It occurs in more than 95% of TS patients. Therefore, oocyte donation is often the only option for women desiring a pregnancy.Objective and hypotheses: Few studies have reported the outcome of spontaneous pregnancies (SP) in TS patients.Method: We evaluated the p...

hrp0089p1-p018 | Adrenals and HPA Axis P1 | ESPE2018

Young Lean Women with Evidence of Both Premature Adrenarche and Pubarche Display a Metabolic, Hormonal and Psychologic Profile that is Similar to that of their Peers with Polycystic Ovary Syndrome

Livadas Sarantis , Bothou Christina , Kanaka-Gantenbein Christina , Chiotis Dimitrios , Angelopoulos Nicholas , Macut Djuro , Chrousos George P

Context: The early activation of adrenal zona reticularis, denoted by increased circulating levels of adrenal androgens before the age of eight years in girls is called premature adrenarche (PA), while the concomitant appearance of pubic hair is termed premature pubarche (PP). Girls with PA-PP display an unfavorable metabolic, hormonal and psychologic profile, compared to their normal peers and are also at an increased risk of developing polycystic ovary syndrome (PCO...

hrp0089p1-p095 | Fat, Metabolism and Obesity P1 | ESPE2018

Variation of Circulating Brain-Derived Neurotrophic Factor According to Gender, Body Mass Index and Metabolic Syndrome Parameters in Adolescents

Bacopoulou Flora , Tsitsimpikou Christina , Mantzou Aimilia , Apostolaki Despoina , Darviri Christina , Efthymiou Vasiliki

Background: Brain-derived neurotrophic factor (BDNF) plays a role in the central regulation of energy balance and has been associated with body mass index (BMI).Objective: The aim of this study was to investigate potential differences in serum BDNF concentrations in adolescents by gender and BMI, as well as possible correlations of circulating BDNF with the adolescentsÂ’ characteristics of metabolic syndrome.Methods: Study part...

hrp0089p2-p134 | Fat, Metabolism and Obesity P2 | ESPE2018

Serum Spexin Concentrations in Adolescent Females with Metabolic Syndrome, Polycystic Ovary Syndrome and Anorexia Nervosa

Bacopoulou Flora , Efthymiou Vasiliki , Apostolaki Despoina , Tsitsimpikou Christina , Tsarouhas Konstantinos , Darviri Christina , Mantzou Aimilia

Background: Spexin is a novel hormone that may potentially impact food intake, weight regulation and body adiposity. Circulating spexin has been associated with obesity and insulin resistance indices in women.Objective: The aim of this study was to determine serum spexin concentrations in adolescent females with metabolic syndrome, with polycystic ovary syndrome (PCOS), with anorexia nervosa as well as in healthy controls, and explore possible relationsh...

hrp0092p1-154 | Thyroid | ESPE2019

Association of Hashimoto's Thyroiditis with Antistreptolysin O titer

Voutetakis Antonis , Kanaka-Gantenbein Christina , Gryparis Alexandros , Dacou-Voutetakis Catherine

Background: Hashimoto's Thyroiditis (HT) is a relatively common autoimmune disorder that involves both cellular and humoral immunity, the latter characterized by the presence of antithyroid antibodies. Nevertheless, despite the large number of relevant studies, the underlying pathogenetic mechanisms still remain unclear; evidence and indications pointing to both genetic and environmental components. Genetic studies have uncovered molecular associations tha...