hrp0089p1-p241 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P1 | ESPE2018

The Comparisons of the Adult Height Gain and the Menarchal Age of the Girls with Central Precocious Puberty after Gonadotropin Releasing Hormone Agonist Alone and Those Treated with Combined Growth Hormone Therapy

Kim Se Young , Kim Minsub

Purpose: To investigate the outcomes of GH therapy combined with GnRH agonist for short girls who diagnosed with idiopathic CPP compared to whom treated with GnRH agonist alone.Methods: We performed retrospective reviews, among 1636 patients managed for CPP, collected data of the 166 girls with CPP treated with GnRHa for 36 months or more from January 2002 to December 2016. We divided groups of patients received GnRHa alone (Group A, n=135) or G...

hrp0084p3-1154 | Puberty | ESPE2015

The Relationships between Serum Vitamin D Level and Precocious Puberty in Korean Girls

Kim Se Young , Woo Yeoloon

Background: The recent articles showed a kind of associations of the serum vitamin D levels and chronic diseases, for example, autoimmune diseases, vascular disorders, as well as malignancies. Also vitamin D deficiency impacts normal growth and maximal bone mineral accretion in puberty. Of pediatric population in Korea, the prevalence of cases of vitamin D deficiency and precocious puberty were continuously increasing nowadays.Objective and hypotheses: W...

hrp0092p1-340 | Fat, Metabolism and Obesity (2) | ESPE2019

Secular Change in Waist Circumference and Waist-Height Ratio in Korean Children and Adolescents Over 10 Years and Effort to Identity Optimal Cutoff for Cardiometabolic Risk

Kim Se Young , Kim Jae Hyun

Purpose: The aims of this study were to identify the secular changes of WC and WHR, to compare WC with the prior Korean reference, to confirm the distribution of mean WHR values by age and sex, and to determine if WHR cutoff value of 0.5 is an appropriate predicting factor of cardiometabolic risk in childhood, using nationally representative data in children and adolescents.Methods: We performed a retrospective, cross-se...

hrp0086p2-p946 | Thyroid P2 | ESPE2016

The Aim of This Study was to Recognize Difference between Transient Congenital Hypothyroidism (TCH) from Permanent Congenital Hypothyroidism by Determining Clinical Characteristics, Laboratory Tests and Imaging Studies

Kim Se Young , Kim Min Sub

Methods: We performed retrospective study using database of the patients with congenital hypothyroidism treated with or without Levo-Thyroxine at Bundang Jesaeng General Hospital, from January 1998 to February 2016. Their ages, birth weights, gestational ages, symptoms, ages at diagnosis and treatment were recorded. We measured TSH, free thyroxine (FT4), triiodothyronine (TT3) levels at diagnosis and treatment, and those levels at one, two and three months after treatment. Thy...

hrp0082p2-d2-551 | Puberty and Neuroendocrinology (1) | ESPE2014

The Effect of Combined GH and GnRH Agonist Treatment for Near-Final Height Improvement in True Precocious Puberty and Early Puberty

Kim Se Young , Kim Eun Young , Yi Kyung Hee

Purpose: The goal of treatment for true precocious puberty (TPP) and early puberty with GnRH agonist (GnRHa) is to prevent loss of genetic potential of target height (TH). And to regress secondary sex characteristics appropriate for patientÂ’s age. But some patientÂ’s growth velocity (GV) after treatment would decline and suggest that final height (FH) was not improved. So, we investigated the effect of combined GH and GnRHa treatment for near-FH (NFH) improvement....

hrp0082p3-d3-949 | Puberty and Neuroendocrinology (1) | ESPE2014

The Perception of Body Image and Self-Esteem in Girls with Precocious Puberty, Being Treatment with GnRH Analogue

Kim Eun Young , Choi Min Sun , Kim Se Young , Hwang Il Tae

Background: Precocious puberty (PP) is associated with psychological and behavioral problems. However, little is known about body image and psychological features in girls with PP, being treatment with GnRH analogues.Objective and hypotheses: This study aimed to evaluate the perception of body image and self-esteem in girls with PP, were receiving GnRH analogue therapy.Method: From March to August 2013, 82 girls with PP with GnRH a...

hrp0089p3-p248 | Growth & Syndromes P3 | ESPE2018

Prediction of Response to Growth Hormone Treatment in Korean Girls with Turner Syndrome

Jung Mo Kyung , Kim Se Young , Lee Ji-Eun , Kim Hae Soon , Yu Jeesuk , Yoo Eun-Gyong

Purpose: Growth hormone (GH) treatment has become common practice in Turner syndrome (TS) to improve final adult height. However, there are only a few studies on the analysis of good responders to GH treatment in TS. The aim of this study is to predict the responsiveness to growth hormone therapy in Turner syndrome.Methods: Among 197 TS patients registered in LG Growth study, 92 patients were excluded because of systemic illness or hypothyroidism. The cl...

hrp0089p1-p107 | Fat, Metabolism and Obesity P1 | ESPE2018

Serum Uric Acid Level and Its Association with Metabolic Syndrome in Korean Adolescents

Jung So Yoon , Lee Young Ah , Kim Jae Hyun , Lee Seong Yong , Kim Se Young , Shin Choong Ho , Yang Sei Won

Background: Elevated serum uric acid (UA) levels are associated with metabolic syndrome (MS), cardiometabolic risk factors (CMRFs) and non-alcoholic fatty liver disease (NAFLD) in adults. However, little is known about usefulness of UA to predict MS in adolescents. As the prevalence of obesity among pediatric population has been increasing, it is important to know the factors associated with the CMRFs to prevent future development of diabetes and cardiovascular disease.<p ...

hrp0092p1-431 | Thyroid (2) | ESPE2019

The Relationship Between Perfluoroalkyl Compounds Concentrations at Ages 2, 4, and 6 Years and Thyroid Function in Early Childhood: A Prospective Cohort Study

Young Kim Hwa , Kim Kyoung-Nam , Ah Lee Young , Lim Youn-Hee , Inhyang Kim Johanna , Kim Bung-Nyun , Oh Se-Young , Hong Yun-Chul , Ho Shin Choong

Backgrounds: Perfluoroalkyl compounds (PFCs) have been suggested as potential thyroid disrupting chemicals. However, previous studies about the associations between PFCs and childhood thyroid function are scarce, and inconclusive. We evaluated the PFC exposure in Korean preschool children, and investigated the temporal relationship with thyroid hormone concentration.Methods: From a prospective the Environment and Develop...

hrp0089p1-p090 | Diabetes &amp; Insulin P1 | ESPE2018

Increasing Trend of Fasting Plasma Glucose Levels and Impaired Fasting Glucose in Non-Diabetic Korean Youth and Young Adults: A Nationally Representative Population-Based Study

Lee Jieun , Ah Lee Young , Hyun Kim Jae , Yong Lee Seong , Ho Shin Choong , Won Yang Sei

Objectives: Diabetes in children and young adults is increasing worldwide. However, the study of change in fasting glucose among general pediatric and young adult population was lacking. The aim of this study was to investigate the secular trend of fasting plasma glucose (FPG) levels in non-diabetic Korean youth and young adults and to evaluate the change in the proportion of impaired fasting glucose (IFG).Methods: Study subjects were Korean youth aged 1...