hrp0094p2-334 | Multisystem endocrine disorders | ESPE2021

Serologic Testing for Celiac Disease and Gluten Intolerance in a Singaporean paediatric endocrine and growth clinic.

Lee Warren ,

Up to 10 % of short stature has been estimated to be due to celiac disease. Celiac disease has been considered a rare condition outside of the Western world but recent publications (Singh P et al, Clin Gastroenterol Hepatol 2018 Jun 16 (6): 823-836, Yuan J et al, Clin Gastroenterol Hepatol 2017 Oct;15(10): 1572-1579) have shown that celiac disease is also present in Asians. While Tissue Transglutaminase IgA (tTg-IgA) has been considered to be a sufficiently sensitive test to e...

hrp0089p3-p319 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

The Relationship Between Prolactin and Development of Puberty in Girls with Early Breast Development

Lee Seong Yong

Background: Prolactin (PRL) stimulates mammary glands and milk production in adult women. Also, high PRL level causes gonadal dysfunction by suppression of gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH).Purpose: The aim of this study was to evaluate, if any, the relationship between PRL level and development of puberty in girls with precocious breast development.Methods: One hundred and ten girls with onset of b...

hrp0086p2-p956 | Thyroid P2 | ESPE2016

Perinatal Factors Associated with Neonatal Thyroid Stimulating Hormone in Normal Newborns

Lee Seong Yong

Background: Neonatal thyroid stimulating hormone (TSH) is influenced by several factors. But the effects are not consistent but different depending on subjects and kind of blood sample.Objective and hypotheses: This study was to evaluate the effect of neonatal, maternal, and delivery factors on neonatal TSH of healthy newborns.Method: Medical records of 713 healthy infants born through normal vaginal delivery were reviewed. TSH lev...

hrp0092p1-349 | Fat, Metabolism and Obesity (2) | ESPE2019

Prevalence of Dyslipidemia in Korean Youth Over 10 Years: Data from the Korea National Health and Nutrition Examination Survey 2008-2017

Lee Jieun , Kim Jae Hyun

Objectives: Dyslipidemia begins and continues in youth and is a major risk factor for adult-onset cardiovascular disease. The aim of this study was to investigate the prevalence and trend of dyslipidemia in Korean youth and its trends for 10 years.Methods: Study subjects were Korean youth aged 10-18 years who participated in the Korea National Health and Nutrition Examination Survey (KNHANES). A total of 7,466 eligible p...

hrp0089p1-p007 | Adrenals and HPA Axis P1 | ESPE2018

Birth Incidence, Age at Diagnosis, Mortality in Congenital Adrenal Hyperplasia in Korea: A Nationwide Population-based Study

Kim Jihyun , Lee Jong Bin

Background: Congenital adrenal hyperplasia (CAH) is a disease inherited by autosomal recessive manner and one of the most common congenital metabolic disorders. The incidence of CAH has been reported mainly through neonatal screening tests, mostly for 21-OHD. It is reported that 21-OHD occurs one in 15,000 people per year. However, there are few studies on all types of CAH incidence including 21-OHD. CAH is a rare disease, studies on large populations are needed to identify a ...

hrp0089p3-p303 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

Morning Basal Luteinizing Hormone, A Good Screening Tool for Diagnosing Central Precocious Puberty

Hyuk Jung In , Min Lee Dong

Background: The current standard method to diagnose central precocious puberty(CPP) is gonadotropin releasing hormone stimulation test (GnRHST). But, it is inconvenient for children because of time-consuming and multiple samples. This study aimed to present utility of morning basal luteinizing hormone (LH) for the screening of central precocious puberty with emphasis on the influence of diurnal variation.Methods: This study is a retrospective review of 1...

hrp0084p3-709 | Diabetes | ESPE2015

Elevated HbA1c and Cardiometabolic Risk Factors in Korean Children and Adolescents: Data from the Korean National Health and Nutrition Examination Survey, 2011–2012

Lee Jieun , Kim Jae Hyun

Background: Prediabetes often precedes type 2 diabetes, which is associated with obesity and increased risk of developing cardiovascular disease. Haemoglobin A1c (HbA1c) has been recently recommended as a useful tool for the diagnosis of diabetes and prediabetes.Objective and hypotheses: We investigated whether prediabetes according to HbA1c was associated with cardiometabolic risk factors in Korean children and adolescents.Method:...

hrp0094p1-192 | Thyroid B | ESPE2021

Analysis of hypothyroidism NGS test in Korean patients with congenital hypothyroidism in a single center

Jung So Yoon , Lee Jeongho ,

Introduction: Thyroid hormone is known as greatly influence on growth and development in fetuses and newborns. If the detection of the disease is delayed, hypothyroidism can cause irreversible damage, so early detection and treatment is very important. Hypothyroidism can be divided into permanent and temporary cases depending on the duration of treatment, but there is no predictor that can completely differentiate those two. However, as genes related to hypoth...

hrp0089p1-p090 | Diabetes & Insulin P1 | ESPE2018

Increasing Trend of Fasting Plasma Glucose Levels and Impaired Fasting Glucose in Non-Diabetic Korean Youth and Young Adults: A Nationally Representative Population-Based Study

Lee Jieun , Ah Lee Young , Hyun Kim Jae , Yong Lee Seong , Ho Shin Choong , Won Yang Sei

Objectives: Diabetes in children and young adults is increasing worldwide. However, the study of change in fasting glucose among general pediatric and young adult population was lacking. The aim of this study was to investigate the secular trend of fasting plasma glucose (FPG) levels in non-diabetic Korean youth and young adults and to evaluate the change in the proportion of impaired fasting glucose (IFG).Methods: Study subjects were Korean youth aged 1...

hrp0089p1-p185 | Growth & Syndromes P1 | ESPE2018

Growth Outcome in Girls with Idiopathic Central Precocious Puberty Treated with Gonadotropin-releasing Hormone Agonist

Sang Lee Hae , Hwang Jin Soon

Objective: Gonadotropin-releasing hormone agonists (GnRHa) are the treatment of choice for central precocious puberty (CPP) and have been widely used for decades. We determined the effect of GnRHa treatment on auxological outcomes of girls with idiopathic CPP.Methods: This study included 84 girls treated monthly with depot leuprolide acetate who had reached adult height. We compared their final adult height (FAH) with their initial predicted adult height...