hrp0092p1-233 | Growth and Syndromes (to include Turner Syndrome) (1) | ESPE2019

Growth Patterns Over Two Years After Birth According to the Birth Weight and Length Percentile in Children Born Preterm

Kim Seulki , Choi Yujung , Lee Seonhwa , Lee Yoonji , Lee Nayoung , Ahn Moonbae , Kim Shinhee , Cho Wonkyoung , Cho Kyoungsoon , Jung Minho , Suh Byungkyu

Purpose: This study aimed to analyze growth patterns during the first two years after birth according to the birth weight and length percentile in children born preterm, and to investigate factors affecting postnatal growth of these children.Methods: Eighty-two preterm neonates with a gestational age below 37 weeks who followed up until 24 months of corrected age (CA) were retrospectively reviewed. Length, weight and hea...

hrp0092p3-117 | Fat, Metabolism and Obesity | ESPE2019

Comparison of Different Criteria for the Definition of Insulin Resistance and Its Relation with Metabolic Risk in Overweight and Obese Adolescents

Lee Seonhwa , Choi Yujung , Kim Seulki , Lee Nayeong , Lee Yoonji , Ahn Moonbae , Kim Shinhee , Cho Wonkyoung , Cho Kyoungsoon , Jung Minho , Suh Byungkyu

This study aimed to compare cut-off points corrected for age and gender (CCOP) with fixed cut-off points (FCOP) for fasting plasma insulin and homeostasis model assessment-insulin resistance (HOMA-IR) for the diagnosis of IR in Korean obese children and adolescents and to identify IR applying CCOP and FCOP using as outcome the presence of dyslipidemia and Metabolic syndrome (MetS).We performed a cross sectional analysis of data from 195 adolescents aged ...

hrp0092p2-122 | Fat, Metabolism and Obesity | ESPE2019

Insulin-like Growth Factor-1 and Binding Protein-3 in Children with Metabolic Syndrome

Lee yoonji , Ahn Moonbae , Kim Seulki , Choi yujung , Cho Wonkyung , Jung Minho , Suh Byung-Kyu

Purpose: To examine the association of Insulin-like growth factor-1 (IGF-1) and binding protein-3 (IGFBP-3) with metabolic parameters of childhood obesity and assess its relationship with the presence of metabolic syndrome (MetS)Methods: A cross-sectional study of total 307 children and adolescents referred for growth assessment was performed. Subjects were divided into three groups based on body mass index (BMI) percent...

hrp0089p2-p026 | Adrenals and HPA Axis P2 | ESPE2018

Early Recognition of Adrenal Insufficiency after Hematopoietic Stem Cell Transplantation During Childhood

Choi Yujung , Lee Seonhwa , ki Kim Seul , Lee Eun Kyoung , Shin Jung-Hyun , Ahn Moon Bae , Cho Won-Kyoung , Jung Min-Ho , Suh Byung-Kyu

Purpose: We try to analyze the prediction capacity of variable factors to diagnose adrenal insufficiency.Methods: We analyzed clinical and laboratory data of 22 children (Male =13) who have been checked regular dose ACTH stimulation test for suspected symptoms after HSCT (Lymphoid leukemia=5, Myeloid leukemia=9, Non-malignant=8) at the Catholic HSCT center from Feb 2013 to Feb 2017 at Seoul St. Mary’s Hospital. A normal response of ACTH stimulation ...

hrp0089p3-p255 | Growth & Syndromes P3 | ESPE2018

Factors Affecting Height Velocity in Normal Prepubertal Children

Kim Seul Ki , Choi Yujung , Lee Seonhwa , Lee Jun Hui , Ahn Moon Bae , Kim Shin Hee , Cho Won Kyung , Cho Kyung Soon , Jung Min Ho , Suh Byung Kyu

Purpose: To analyze the effects of clinical and laboratory factors, including insulin-like growth factor (IGF) levels, on the height velocity of normal prepubertal children.Methods: Ninety-five healthy prepubertal children (33 boys, 62 girls) were enrolled. The mean chronological age of the participants was 6.3±1.4 years, with a height standard deviation score (SDS) of −0.88±0.70. IGF-1, IGF binding protein-3 (IGFBP-3), SDS for anthropome...

hrp0092p2-218 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

The Difference of Body Mass Index (BMI) Score Before and After Gonadotropin-Releasing Hormone Agonist (GnRHa) Treatment in Central Precocious Puberty Girls

Choi Yujung , Lee Seonhwa , Kim Seulki , Ahn Moonbae , Kim Shinhee , Cho Wonkyoung , Cho Kyoungsoon , Jung Minho , Suh Byungkyu

Purpose: We investigated the difference of body mass index (BMI) score before and after gonadotropin-releasing hormone agonist (GnRHa) treatment in central precocious puberty girls (CPP).Methods: Medical records of 188 girls with CPP treated with GnRHa were reviewed. All patients completed the therapy. The patients were categorized into two groups according to initial BMI; normal weight group (BMI < 85 percentile) an...

hrp0094p2-334 | Multisystem endocrine disorders | ESPE2021

Serologic Testing for Celiac Disease and Gluten Intolerance in a Singaporean paediatric endocrine and growth clinic.

Lee Warren ,

Up to 10 % of short stature has been estimated to be due to celiac disease. Celiac disease has been considered a rare condition outside of the Western world but recent publications (Singh P et al, Clin Gastroenterol Hepatol 2018 Jun 16 (6): 823-836, Yuan J et al, Clin Gastroenterol Hepatol 2017 Oct;15(10): 1572-1579) have shown that celiac disease is also present in Asians. While Tissue Transglutaminase IgA (tTg-IgA) has been considered to be a sufficiently sensitive test to e...

hrp0092p2-85 | Diabetes and Insulin | ESPE2019

Clinical Characteristics and Treatment Outcomes in Patients with Autoantibody-negative Ketosis-prone Diabetes

Kim Shin-Hee , Ahn Moon-Bae , Kim Seulki , Choi Yujung , Lee Seonhwa , Cho Won Kyoung , Cho Kyoung Soon , Jung Min Ho , Kyu Suh Byung

Objective: Ketosis-prone diabetes (KPD), characterized by presentation with diabetic ketoacidosis (DKA) in patients lacking the typical features of autoimmune type 1 diabetes, is a heterogeneous syndrome. The objective of this study is to ascertain the presence of A-β+ (autoantibody-negative, β-cell functional reserve) KPD in Korean children and adolescents and to study their characteristics in this group. Method: Diabetes ...

hrp0089p1-p063 | Diabetes &amp; Insulin P1 | ESPE2018

Glucose Intolerance in Survivors of Childhood Hematologic Disorders

Lee Seonhwa , Choi Yujung , Kim Seul ki , Ahn Moonbae , Chun Min-Kyo , Kim Shinhee , Cho Wonkyoung , Cho Kyoungsoon , Jung Minho , Suh Byungkyu

Purpose: To investigate overall characteristics of glucose intolerance in childhood survivors of hematologic diseases and suggest risk factors which increase A1c (glycated hemoglobin) level.Methods: Based on a retrospective review of 394 children who were diagnosed with acute leukemia or aplastic anemia between 2015 and 2016 under the age of 15, glucose intolerance was observed in 14 patients. A definition of glucose intolerance was A1c above 5.7%. Auxol...

hrp0089p1-p265 | Thyroid P1 | ESPE2018

HLA Alleles and Amino Acid Variants of HLA-A, -B, -C, -DRB1, -DQB1, -DPB1 Molecules in Early-Onset Autoimmune Thyroid Disease

Cho Won Kyoung , Shin Dong Hwan , Kim Seul Ki , Lee Seonhwa , Choi Yujung , Ahn Moonbae , Baek In Cheol , Jung Min Ho , Kim Tai-Gyu , Suh Byung-Kyu

Objective: We try to investigate the polymorphisms and amino acid variants of HLA-A, -B, -C, -DRB1, -DQB1, -DPB1 molecules in early-onset AITD.Methods: The genotypes of HLA-A, B, C, DRB1, DQB1, and DPB1 on AITD were analyzed in 102 Korean children with AITDs (Graves’ disease (GD)=62, Hashimoto’s disease (HD)=40) and 142 healthy control using sequence-based typing. Analysis of variant amino acids was performed across the genotyping results with ...