hrp0086p2-p330 | Diabetes P2 | ESPE2016

Lipid Metabolism in Children with Diabetes Mellitus Type 1

Latyshev Dmitri , Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Lobanov Yuri

Objective and hypotheses: To study the lipid metabolism in children with diabetes type 1.Method: It was included 44 children (33 girls), the average age – 10.2±3.3 years. Patients were divided: group 1 (less than 5 years) – 23 children (17 girls), mean age 9.8±3.6, the average length of diabetes 2.08±1.5 years. The second (over 5 years) – 21 children (16 girls), mean age of 11.6±2.4, the average length – 7.5±1...

hrp0082p3-d1-767 | Fat Metabolism & Obesity | ESPE2014

Prevalence Metabolic Syndrome and Its Components Among Children with Obesity

Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Samsonova Lubov , Kolomina Irina

Background and aims: To study the prevalence of metabolic syndrome and its components (impaired fasting and after overload glucose, type 2 diabetes mellitus, low cholesterol HDL, and high triglycerides) in children with obesity.Methods: This research includes 550 (65.8% boys) children, recruited from Pediatric Endocrinology Department, with abdominal obesity. We measured BMI, waist circumference, blood pressure with standard instrumentation and glucose (...

hrp0082p3-d3-940 | Puberty and Neuroendocrinology (1) | ESPE2014

Inhibin B in the Boys with Constitutional Delay of Puberty: Relationship with Gonadotropins, Testosterone, and Anti-Müllerian Factor

Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Samsonova Lubov

Objective: The aim of this study were to investigate the level of inhibin B and its relationship with testosterone, anti-Müllerian factor, basal, and GnRH-stimulated gonadotropin hormones (LH and FSH) concentration in boys with constitutional delay of puberty.Material and methods: In the study were included 15 boys (mean age 14.5±1.6 years) in Tanner stages 1–2. The investigation consists of genital examination with prader orchidometer, de...

hrp0084p3-796 | DSD | ESPE2015

Tumours of Gonads in Patients with Disorders of Sex Development – 46,XY Gonadal Dysgenesis

Latyshev Oleg , Samsonova Lubov , Okulov Alexey , Kiseleva Elena , Okmynuan Guar

Background: Disorders of sex development, especially with Y chromosome material, are the main factor of an increased risk of gonadal tumour. The main idea of this study was to investigate the prevalence of gonad tumours in patients with 46,XY gonadal dysgenesis.Methods: This study included 9 patients with 46,XY gonadal dysgenesis: seven patients with partial and two with total gonadal dysgenesis. Among nine patients there were two patients with Frasier s...

hrp0092rfc5.3 | Thyroid | ESPE2019

Experience of Thyroid Surgery in Children with Intraoperative Neuromonitoring

Brovin Dmitriy , Anikiev Alexander , Danilenko Oleg , Vyazmenov Edward , Bezlepkina Olga , Kuznetsov Nikolay

Introduction: Thyroid surgery in children is associated with high risk of recurrent laryngeal nerves (RLN) damage. It is due to complex and variable anatomy, high bleeding which decreasing visualization and requiring instrumental hemostasis. Large goiters change of syntopy, metastatic process requires bigger aggression and volume of intervention. The risk of damage significantly increases during repeated operations due to the scar process. There is significant...

hrp0092p1-147 | Thyroid | ESPE2019

Intrathyroidal Ectopia of Thymus in Children: Frequency, Ultrasound, Evolution

Okminyan Goar , Rogova Olga , Pykov Mihail , Lavrova Tatyana , Kiselyova Elena , Latyshev Oleg , Samsonova Lyubov

Objectives: to study the frequency, ultrasound characteristics and the evolution of intrathyroidal ectopia of thymus(IET) in children.Materials and Methods: as part of an epidemiological study (2014-2017), an assessment consists of incidence of IET in pre-puberty children, which using ultrasound of 1164 patients (604 girls, 560 boys). As part of a clinical study (2014-2019), the ultrasound characteristics and the evoluti...

hrp0092p3-224 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Clinical and Laboratory Characteristics of Different Various Types of Gonadal Dysgenesis in Girls with Hypergonadotropic Hypogonadism

Kabolova Kseniya , Oleg Latyshev , Lubov Samsonova , Elena Kiseleva , Goar Okminyan , Kristina Kokoreva , Elvira Kasatkina

Objective: to evaluate clinical and laboratory characteristics of various types of gonadal dysgenesis in girls with hypergonadotropic hypogonadism.Methods: 17 girls with hypergonadotropic hypogonadism (13.9±3.72) were examined. Inclusion criteria: characteristics of delayed puberty, no disorders of sex development, presence of müllerian duct derivatives, high levels of gonadotrophins. Tanner stage, antropometri...

hrp0092p3-242 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Clinical and Laboratory Characteristics of Patients with Different Variants of Gonadal Dysgenesis

Latyshev Oleg , Sannikova Ekaterina , Samsonova Lubov , Kiseleva Elena , Okminyan Goar , Kasatkina Elvira , Volodko Elena , Dondup Olga

Objective: To study clinical and laboratory characteristics of patients with disorders of sex development (DSD) 45,X/46,XY and 46,XY, partial gonadal dysgenesis.Subjects and Methods: It was included 27 patients with disorders of gonadal dysgenesis at birth to 9 years, which were divided into groups based on cytogenetic survey – DSD 46,XY, partial gonadal dysgenesis (n=10) and DSD 45,X/46,XY (n&...

hrp0092p3-253 | Thyroid | ESPE2019

Child Thyrotoxicosis Syndrome: Structure and Characteristics

Evsyukova Evgeniya , Kolomina Irina , Bukin Sergey , Kisileva Elena , Latyshev Oleg , Okminyan Goar , Samsonova Lyubov

Objective: To study the structure and characteristics of child thyrotoxicosis syndrome.Materials and Methods: At the 1st stage, medical records of patients treated at the Endocrinology Unit of the Children's Hospital named after Z.A. Bashlyaeva of the City of Moscow in 2014-2018 (n=4530) were analyzed. At the 2nd stage, a primary examination of 106 children 3 to 17 years old with a diagnosis of thyrotoxi...

hrp0089p2-p067 | Diabetes & Insulin P2 | ESPE2018

Frequency of Occurrence of MODY in the Population of Diabetic Patients in St. Petersburg

Turkunova Mariia , Bashnina Elena , Berseneva Olga , Glotov Oleg , Glotov Andrei , Serebryakova Elena

The purpose of this study is to determine the frequency of occurrence and molecular-genetic characteristics of MODY in patients with diabetes mellitus aged 1 to 18 years, residents of St. Petersburg.Materials and methods: In St. Petersburg in 2017, there were 1620 patients with diabetes mellitus under the age of 18 years. 54 of them had evidence of hereditary variants of diabetes with chronic hyperglycemia at normal c-peptide indices for 2 years after th...