hrp0089wg4.5 | ESPE Diabetes Technology and Therapeutics Working Group | ESPE2018

Analyzing and Reporting of Sensor Glucose Levels

Nimri Revital

Background: Since the publication of the Diabetes Control and Complications Trial results two decades ago, glycated haemoglobin (A1c) has remained the only validated measurement of glycemic control and marker for future complications. The growing use of continuous glucose monitoring (CGM) has opened a new era of measuring and following glycemia and it associated outcomes. These new available glucose variables can provide a broader insight to personalized glyce...

hrp0086wg5.4 | ESPE Diabetes Technology and Therapeutics Working Group | ESPE2016

Use of Dual Hormone (Glucagon) v. Single Hormone (Insulin) in the Treatment of Diabetes with Close-loop System

Nimri Revital

Background: Blood glucose levels are physiologically controlled by insulin and counter-regulatory hormones, mainly glucagon. Type 1 diabetes patients are deficient in insulin and some level also glucagon. Therefore, bi-hormonal closed-loop system seems to be the best way to control glycemia.Objective and hypotheses: There are two main approaches to add glucagon: (a) as safety measures for rescue in case of hypoglycemia (2) as a mean to optimize metabolic...

hrp0084wg2.4 | Diabetes Technology and Therapeutics Thursday, 1 October | ESPE2015

Blood Glucose Monitoring: Which is Better: Continuous Real-Time or Episodic Real-Time on Demand? PRO

Nimri Revital

Background: The use of continuous glucose monitoring has been proven beneficial in improving glucose control. Nevertheless, its use by the patients is still limited with a high discontinuation rate, especially in the pediatric population. Real-life data showed a 30% adherence to treatment after 1 year of use.Objective and hypotheses: The most likely explanation for the sensor being underutilized is the significant burden related to its use fraught with t...

hrp0092p2-267 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

An Intriguing Co-Occurrence of MURCS and VACTERL Association: A Case Report and Review of the Literature

Averbuch Noa Shefer , Shvalb Naama Fisch , Nimri Revital , Phillip Moshe , Orenstein Naama

Background: MURCS association is a rare developmental disorder that primarily affects the reproductive and urinary systems. MURCS is an acronym which stands for (MU)llerian, (R)enal, (C)ervicothoracic (S)omite abnormalities. Males and females with MURCS association often have short stature and might suffer from hearing loss. MURCS anomalies are present at birth but may not be noticed until puberty, and then present as primary amenorrhea, or discovered incident...

hrp0089p2-p096 | Diabetes & Insulin P2 | ESPE2018

The Incorporation of Available Technologies for Diabetes Care Among Different Worldwide Centers: The ESPE/ISPAD Working Group on Diabetes Technology Survey

Dovc Klemen , Shalitin Shlomit , Hanas Ragnar , Boughton Charlotte , Musolino Gianluca , Battelino Tadej , Nimri Revital , Phillip Moshe

Objective: International Societies for diabetes care are aiming to facilitate and improve the uptake of diabetes technologies. This survey investigated healthcare professional (HCP) evaluation of the role of technology in diabetes care within their centres.Methods: Between April to November 2017, 215 HCPs from six continents (132 Europe, 36 Asia, 23 North and 7 South America, 9 Africa and 8 Australasia) replied to an online survey and provided data for a...

hrp0094p2-170 | Diabetes and insulin | ESPE2021

Diabetes Ketoacidosis Recovery in Youth with Newly Diagnosed and Established Type 1 Diabetes

Zilberberg Keren Smuel , Shalitin Shlomit , Yackobovitch-Gavan Michal , Phillip Moshe , Nimri Revital ,

Objective: To describe the differences in metabolic parameters and in time to recovery from Diabetes ketoacidosis (DKA), between children and adolescents with newly diagnosed compared with established Type 1 Diabetes (T1DM).Methods: A single center, retrospective study. The cohort comprised 356 children and adolescents with T1DM who had DKA during 2008-2018. Data were obtained from the patientsÂ’ medical files. Recov...

hrp0086p2-p711 | Endocrinology and Multisystemic Diseases P2 | ESPE2016

Growth and Pubertal Patterns in Young Survivors of Childhood Acute Lymphoblastic Leukemia

Shalitin Shlomit , Elitzur Sarah , Yaniv Isaac , Stark Batia , Yackobovitz-Gavan Michal , Lebenthal Yael , Phillip Moshe , Huri-Shtrecher Revital

Background: Childhood acute lymphoblastic leukemia (ALL) survivors are at increased risk for endocrine late effects.Objective and hypotheses: To evaluate growth and pubertal patterns in patients diagnosed with childhood ALL and to identify risk factors for impaired growth and puberty.Method: Retrospective chart review with longitudinal assessment of anthropometric measurements and pubertal status of 183 childhood ALL survivors diag...

hrp0082fc9.5 | Beta cells | ESPE2014

Transient Neonatal Diabetes in Adulthood: Metabolic and Neurodevelopmental Outcomes

Le Bourgeois Fleur , Busiah Kanetee , Abu-Amara-Olivieri Sawsan , Bachere Nadege , Bertrand Anne-Marie , Bourron Olivier , David Paul , De Boisvilliers Fabienne , Deumier Bernard , deVries Liat , Jelliman Stephanie , Le Tallec Claire , Martin-Dessila Amelie , Nimri Paul , Paoli Anne , Perrin Mireille , Stuckens Chantal , Ythier Hubert , Pouvreaux Nathalie , Bellane-Chantelot Christine

Background: Transient neonatal diabetes mellitus (TNDM) is a rare genetic β-cell dysfunction leading to hyperglycaemia that resolves in early childhood. About 80% of patients relapse during adolescence or adulthood. Some of these patients suffer from neurodevelopmental defect. Long-term outcome has been poorly investigated.Objective and Hypotheses: To investigate metabolic and neurologic outcomes in adults affected with TNDM.M...