hrp0082p3-d1-767 | Fat Metabolism & Obesity | ESPE2014

Prevalence Metabolic Syndrome and Its Components Among Children with Obesity

Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Samsonova Lubov , Kolomina Irina

Background and aims: To study the prevalence of metabolic syndrome and its components (impaired fasting and after overload glucose, type 2 diabetes mellitus, low cholesterol HDL, and high triglycerides) in children with obesity.Methods: This research includes 550 (65.8% boys) children, recruited from Pediatric Endocrinology Department, with abdominal obesity. We measured BMI, waist circumference, blood pressure with standard instrumentation and glucose (...

hrp0082p3-d3-940 | Puberty and Neuroendocrinology (1) | ESPE2014

Inhibin B in the Boys with Constitutional Delay of Puberty: Relationship with Gonadotropins, Testosterone, and Anti-Müllerian Factor

Latyshev Oleg , Kiseleva Elena , Okminyan Goar , Samsonova Lubov

Objective: The aim of this study were to investigate the level of inhibin B and its relationship with testosterone, anti-Müllerian factor, basal, and GnRH-stimulated gonadotropin hormones (LH and FSH) concentration in boys with constitutional delay of puberty.Material and methods: In the study were included 15 boys (mean age 14.5±1.6 years) in Tanner stages 1–2. The investigation consists of genital examination with prader orchidometer, de...

hrp0084p3-796 | DSD | ESPE2015

Tumours of Gonads in Patients with Disorders of Sex Development – 46,XY Gonadal Dysgenesis

Latyshev Oleg , Samsonova Lubov , Okulov Alexey , Kiseleva Elena , Okmynuan Guar

Background: Disorders of sex development, especially with Y chromosome material, are the main factor of an increased risk of gonadal tumour. The main idea of this study was to investigate the prevalence of gonad tumours in patients with 46,XY gonadal dysgenesis.Methods: This study included 9 patients with 46,XY gonadal dysgenesis: seven patients with partial and two with total gonadal dysgenesis. Among nine patients there were two patients with Frasier s...

hrp0086p2-p425 | Gonads & DSD P2 | ESPE2016

Constitutional Delay of Puberty: Clinical and Hormonal Characteristics of Patients

Osipova Lubov , Latyshev Oleg , Samsonova Lubov , Okminyan Goar , Kiseleva Elena , Kasatkina Elvira

Objective and hypotheses: To examine anthropometric, hormonal characteristics and their relationship in boys with constitutional delay of puberty (CDP).Method: The study included 47 boys older 13.2 year old with CDP. It evaluated anthropometric indicators, bone age and hormonal status.Results: The patients were divided: the first group consisted of 25.5% (12/47) of boys with pathological growth (Median/Me Ht-SDS=−2.3). Of the...

hrp0092p3-242 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Clinical and Laboratory Characteristics of Patients with Different Variants of Gonadal Dysgenesis

Latyshev Oleg , Sannikova Ekaterina , Samsonova Lubov , Kiseleva Elena , Okminyan Goar , Kasatkina Elvira , Volodko Elena , Dondup Olga

Objective: To study clinical and laboratory characteristics of patients with disorders of sex development (DSD) 45,X/46,XY and 46,XY, partial gonadal dysgenesis.Subjects and Methods: It was included 27 patients with disorders of gonadal dysgenesis at birth to 9 years, which were divided into groups based on cytogenetic survey – DSD 46,XY, partial gonadal dysgenesis (n=10) and DSD 45,X/46,XY (n&...

hrp0086p2-p403 | Gonads & DSD P2 | ESPE2016

Endocrine Risk Factors of Testicular Cancer of Children and Teenagers with Testicular Microlithiasis

Kabolova Kseniya , Latyshev Oleg , Samsonova Lubov , Kiseleva Elena , Okminyan Goar , Kasatkina Elvira

Objective and hypotheses: To evaluate endocrine risk factors of testicular cancer of children with testicular microlithiasis.Method: Under research were 74 patients with testicular microlithiasis (average 11.41±4.02). Heredity, case history, endocrine diseases, anthropometric indicators, ultrasound of the scrotum were evaluated.Results: At 20 of 74 (27%) children microlithiasis was combined with strong risk factors of testicle...

hrp0086p2-p414 | Gonads & DSD P2 | ESPE2016

Disorders of Sex Development 45,X/46,XY: Clinical and Laboratory Characteristics of Patients

Sannikova Ekaterina , Latyshev Oleg , Samsonova Lubov , Kiseleva Elena , Okminyan Goar , Kasatkina Elvira

Objective: To study clinical and laboratory characteristics of patients with disorders of sex development (DSD) 45,X/46,XY.Subjects and methods: It was included 248 patients with genital ambiguity, which were divided into groups based on cytogenetic survey. All children with mosaicism 45,X/46,XY evaluated the structure of the external genitalia on the external masculinization score (EMS, range 0–12), ultrasound examination, the definition of anti-Mu...

hrp0086p2-p967 | Thyroid P2 | ESPE2016

Postoperative Complications of Thyroidectomy in Children with Nodular Goiter

Rogova Olga , Okminyan Goar , Samsonova Lubov , Kiseleva Elena , Latyshev Oleg , Kasatkina Elvira , Mirakov Kirill , Okulov Alexey

Background: Objective and hypotheses: Rate the frequency and structure of post-operative complications of thyroidectomy in children with nodular goiter.Method: Twenty-seven children, 20 girls (14.5±3.64 years) and seven boys (14.68±4.09 years), which were performed thyroidectomy about multinodular goiter (n=23) and single-node goiter (n=4) from 2003 to 2015. Were evaluated complaints of patients, physica...

hrp0084p3-636 | Autoimmune | ESPE2015

Functional Status of the Thyroid Gland in Children with Diabetes Mellitus Type 1

Latyshev Oleg , Samsonova Lubov , Okminyan Goar , Kiseleva Elena , Lobanov Yuryi , Latyshev Dmitriy

Background and aims: To investigate the functional status of the thyroid gland in children with diabetes mellitus type 1.Materials and methods: In the study were included 29 (13 boys, mean age 11.3±2.7 years) patients with diabetes mellitus type 1 from iodine deficient region. The examination included thyroid ultrasound and assessment of the functional state of the thyroid system: thyroid-stimulating hormone (TSH), fT4, fT3, th...

hrp0084p3-723 | Diabetes | ESPE2015

The Investigation of Frequency of Diabetic Ketoacidosis in Children with New-onset Diabetes Mellitus Type 1

Okminyan Goar , Samsonova Lubov , Kiseleva Elena , Latyshev Oleg , Evsukova Evgenia , Kolomina Irina , Kasatkina Elvira

Background and aims: The aim of this study was to investigate the frequency of diabetic ketoacidosis and diagnostic mistakes in onset diabetes mellitus type l in children and their relationship with age.Materials and methods: In this study were included 269 patients (from 7 month to 17 years) in onset diabetes mellitus type l since 2010–2013. All patients were divided in to two groups. The first group consists of 92 patients (children were younger t...