hrp0086wg5.3 | ESPE Diabetes Technology and Therapeutics Working Group | ESPE2016

Use and Discontinuation of Continuous Subcutaneous Insulin Infusion and Continuous Glucose Monitoring in Paediatric Patients with Type 1 Diabetes: Rates and Causes

Shalitin Shlomit

Background: A large percentage of pediatric patients with type 1 diabetes (T1D) do not achieve their glycaemic targets. The most impactful benefit can be achieved by improving the implementation of novel technologies developed to manage diabetes.Objective and hypotheses: Two novel technologies were introduced to help patients with T1D achieve glycaemic control: continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM). They ...

hrp0092p2-115 | Fat, Metabolism and Obesity | ESPE2019

The Prevalence of Severe Obesity and Related Comorbidities has Increased During the Last Decade Among Children and Adolescents Referred for Evaluation at the Obesity Clinic

Avnieli Yael , Phillip Moshe , Shalitin Shlomit

Background/Aims: Childhood obesity has increased markedly during the past decades.The aim of the study was to examine the changes in trends of severe obesity and related comorbidities among children and adolescents referred for evaluation at the obesity clinic in a tertiary care center in Israel.Methods: The study included patients aged 2-18 years referred for evaluation due to obesity (BMI > 9...

hrp0089p3-p277 | Multisystem Endocrine Disorders P3 | ESPE2018

Wolman Disease: Long-Term Endocrine and Metabolic Comorbidities

Bello Rachel , Stein Jerry , Phillip Moshe , Shalitin Shlomit

Introduction: Wolman Disease [WD] is a rare, autosomal recessive disease caused by lysosomal acid lipase deficiency and characterized by accumulation of cholesterol-esters and triglycerides primarily in the liver and spleen. Patients present within the first year of life with a rapidly progressive disease.Case: A girl born to consanguineous parents was diagnosed with WD due to characteristic manifestations and family history (genetically confirmed). At t...

hrp0092p1-187 | Diabetes and Insulin (1) | ESPE2019

Course of Puberty and Growth Spurt in Boys with Type 1 Diabetes

Shpitzer Hana , Lazar Liora , Shalitin Shlomit , Phillip Moshe , de Vries Liat

Background: Data on the course of puberty and pubertal growth in boys with Type 1 diabetes (T1D) are sparse.Objectives: To study the course of puberty, pubertal growth and final height in boys with T1D as well as possible factors affecting these.Methods: In this retrospective longitudinal study, 68 boys diagnosed with T1D between 1996-2009 who were pre-pubertal at diagnosis and had...

hrp0089p2-p096 | Diabetes & Insulin P2 | ESPE2018

The Incorporation of Available Technologies for Diabetes Care Among Different Worldwide Centers: The ESPE/ISPAD Working Group on Diabetes Technology Survey

Dovc Klemen , Shalitin Shlomit , Hanas Ragnar , Boughton Charlotte , Musolino Gianluca , Battelino Tadej , Nimri Revital , Phillip Moshe

Objective: International Societies for diabetes care are aiming to facilitate and improve the uptake of diabetes technologies. This survey investigated healthcare professional (HCP) evaluation of the role of technology in diabetes care within their centres.Methods: Between April to November 2017, 215 HCPs from six continents (132 Europe, 36 Asia, 23 North and 7 South America, 9 Africa and 8 Australasia) replied to an online survey and provided data for a...

hrp0082p1-d3-225 | Reproduction (2) | ESPE2014

Treated and Untreated Women with Idiopathic Precocious Puberty: Long-Term General Health Status and Metabolic Outcome Between third and fifth decades

Meyerovitch Joseph , Lebenthal Yael , Antebi Felice , Shalitin Shlomit , de Vries Liat , Phillip Moshe , Lazar Liora

Context: Central precocious puberty (CPP), treated or untreated, may have clinical implications in adulthood.Objective: To assess the general health status and metabolic outcome of former CPP women between the third and fifth decades of life.Design: Case–control study of an historical cohort using the computerized database of a health management organization.Participants: Study group – 148 CPP women...

hrp0084p3-837 | Fat | ESPE2015

Comparison of Two Family-Intervention (Parents Only vs Parent and Child) in the Treatment of Childhood Obesity

Meyerovitch Joseph , Yackobovitch-Gavan Michal , Wolf Dafna , Phillip Moshe , Shalitin Shlomit

Background: Obesity in adolescence is associated with a 70% likelihood of obesity or overweight in adulthood. Hence, effective intervention programs for childhood obesity in high-risk populations are needed.Objectives: i) To compare the efficacy of two intervention strategies, involving parents only vs parent and child, to a control group, in the treatment of childhood obesity. ii) To identify clinical demographical and biochemical predictors for decreas...

hrp0094p2-170 | Diabetes and insulin | ESPE2021

Diabetes Ketoacidosis Recovery in Youth with Newly Diagnosed and Established Type 1 Diabetes

Zilberberg Keren Smuel , Shalitin Shlomit , Yackobovitch-Gavan Michal , Phillip Moshe , Nimri Revital ,

Objective: To describe the differences in metabolic parameters and in time to recovery from Diabetes ketoacidosis (DKA), between children and adolescents with newly diagnosed compared with established Type 1 Diabetes (T1DM).Methods: A single center, retrospective study. The cohort comprised 356 children and adolescents with T1DM who had DKA during 2008-2018. Data were obtained from the patients’ medical files. Recov...

hrp0094p2-347 | Pituitary, neuroendocrinology and puberty | ESPE2021

Optic tract glioma and endocrine disorders- comparison between patients with and without NF1- a single center experience

Gil Margolis Merav , Yackobovitz-Gavan Michal , Toledano Hellen , Phillip Moshe , Shalitin Shlomit ,

Background and Aims: Optic pathway gliomas (OPGs) represent 2-5% of brain tumors in children. OPGs are classified by the anatomic location and whether they are associated with neurofibromatosis type 1 (NF1). Children with OPGs face sequelae related to tumor location and treatment modalities, including visual dysfunction, neurologic deficits, and endocrine dysfunction. The aim of our study was to assess the prevalence of endocrine dysfunctions in patients with ...

hrp0086p2-p711 | Endocrinology and Multisystemic Diseases P2 | ESPE2016

Growth and Pubertal Patterns in Young Survivors of Childhood Acute Lymphoblastic Leukemia

Shalitin Shlomit , Elitzur Sarah , Yaniv Isaac , Stark Batia , Yackobovitz-Gavan Michal , Lebenthal Yael , Phillip Moshe , Huri-Shtrecher Revital

Background: Childhood acute lymphoblastic leukemia (ALL) survivors are at increased risk for endocrine late effects.Objective and hypotheses: To evaluate growth and pubertal patterns in patients diagnosed with childhood ALL and to identify risk factors for impaired growth and puberty.Method: Retrospective chart review with longitudinal assessment of anthropometric measurements and pubertal status of 183 childhood ALL survivors diag...