hrp0086p1-p135 | Bone & Mineral Metabolism P1 | ESPE2016

Low Bone Mineral Density in Adolescents with Leukemia After Hematopoietic Stem Cell Transplantation

Kyoung Cho Won , Bae Ahn Moon , Hee Kim Shin , Soon Cho Kyoung , Hyun Park So , Ho Jung Min , Suh Byung-Kyu

Background: Hematopoietic stem cell transplantation (HSCT) has improved the prognosis of children with malignant hematologic disease. However, it has had significant adverse effects on the endocrine system, including bone health. Limited studies are available to assess osteoporosis in survivors of adolescents after HSCT.Objective and hypotheses: We investigate the bone mineral density (BMD) and endocrinopathy/treatment factors associated with low BMD in ...

hrp0094p1-52 | Bone B | ESPE2021

Impact of Vertebral Fracture on Auxological Profile and Insulin-like Growth Factors of Children after Acute Lymphoblastic Leukemia Treatment

Bae Ahn Moon , Kim Sung Eun , Lee Na Yeong , Ki Kim Seul , Hee Kim Shin , Kyoung Cho Won , Soon Cho Kyoung , Ho Jung Min , Suh Byung-Kyu ,

Purpose: To investigate the overall prevalence of vertebral fractures (VF) following childhood acute lymphoblastic leukemia (ALL) treatment and examine the association of VF with growth trajectory and insulin-like growth factorsMethods: Children (n = 172; 59.3 % male) diagnosed with ALL at age between 2 and 18 years were assessed for VF by screening the lateral thoracolumbar spine radiographs (Genant’s semi-quantitative met...

hrp0082p2-d2-543 | Puberty and Neuroendocrinology (1) | ESPE2014

Time to Menarche After Completing GnRH Agonist in Girls with Central Precocious or Early Puberty

Kim Shin-Hee , Jung In-Ah , Cho Won Kyoung , Cho Kyoung Soon , Park So Hyun , Jung Min Ho , Suh Byoung Kyu

Background: Treatment goals for central precocious puberty (CPP) in girls include preventing short final height due to early epiphyseal closure, and avoiding premature onset of menarche.Objective and hypotheses: Our aim was to evaluate the timing of menarche and the associated factors among patients with idiopathic CPP or early-onset puberty (EP) who were treated with GnRH agonists (GnRHa).Method: We analyzed clinical and laborator...

hrp0082p3-d2-741 | Diabetes (3) | ESPE2014

Incidence of Dyslipidemia and its Association with Glycemic Control in Adolescents and Young Adults with Type 1 Diabetes

Kim Shin-Hee , Jung In-Ah , Cho Won Kyoung , Cho Kyoung Soon , Park So Hyun , Jung Min Ho , Suh Byoung Kyu

Background: Hyperglycemia and dyslipidemia are metabolic abnormalities commonly found in type 1 diabetes.Objective and hypotheses: Limited data are available on the relationship between glycemic control and dyslipidemia in patients with type 1 diabetes. We aimed to investigate the incidence of dyslipidemia and its association with glycemic control in adolescents and young adults with type 1 diabetes.Method: This cross-sectional stu...

hrp0092p2-166 | GH and IGFs | ESPE2019

Prediction of the First-Year Response to Growth Hormone Treatment in Prepubertal Korean Children with Idiopathic Growth Hormone Deficiency: Analysis of Data from the LG Growth Study Database

Cho Wonkyoung , Ahn Moon-Bae , Cho Kyoung Soon , Jung Min Ho , Suh Byung-Kyu

Background: Insufficient data exist for the prediction of the first-year response to growth hormone (GH) treatment in Korean prepubertal children with idiopathic GH deficiency (GHD).Methods: Data from children (n = 345) who were in the LG Growth Study Database or had participated in other relevant clinical trials were used to develop a model. All included patients had been diagnosed with idiopathic GHD with maximum G...

hrp0084p2-375 | Fat | ESPE2015

The Relation of Serum Nesfatin-1 Level with Anthropometric and Metabolic Parameters in Korean Children and Young Adolescents

Kim Shin-Hee , Ahn Moonbae , Jung In-Ah , Jeon Yeon Jin , Cho Won Kyoung , Cho Kyoung Soon , Park So Hyun , Jung Min Ho , Suh Byoung-Kyu

Background: Nesfatin-1, a recently discovered anorexigenic neuropeptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis.Objective and hypotheses: The aim of this study is to evaluate the relation of serum nesfatin-1 level with anthropometric and metabolic parameters in children and adolescents.Method: This study included 78 Korean children and adolescents (42 obese/overweight ...

hrp0092p2-85 | Diabetes and Insulin | ESPE2019

Clinical Characteristics and Treatment Outcomes in Patients with Autoantibody-negative Ketosis-prone Diabetes

Kim Shin-Hee , Ahn Moon-Bae , Kim Seulki , Choi Yujung , Lee Seonhwa , Cho Won Kyoung , Cho Kyoung Soon , Jung Min Ho , Kyu Suh Byung

Objective: Ketosis-prone diabetes (KPD), characterized by presentation with diabetic ketoacidosis (DKA) in patients lacking the typical features of autoimmune type 1 diabetes, is a heterogeneous syndrome. The objective of this study is to ascertain the presence of A-β+ (autoantibody-negative, β-cell functional reserve) KPD in Korean children and adolescents and to study their characteristics in this group. Method: Diabetes ...

hrp0086p2-p776 | Pituitary and Neuroendocrinology P2 | ESPE2016

Central Nervous System Abnormalities on Brain Magnetic Resonance Imaging Among 200 Korean Girls with Central Precocious Puberty

Kim Shin-Hee , Ahn Moon Bae , Cho Won Kyoung , Cho Kyoung Soon , Park So Hyun , Jung Min Ho , Suh Byung-Kyu

Background: Central precocious puberty (CPP) may result from organic lesions, but it is most frequently of idiopathic origin in girls.Objective and hypotheses: The objective of the study was to identify central nervous system abnormalities in girls with CPP.Method: This retrospective study was performed in 3-tertiary care hospitals between 2005 and 2015. During this period, 200 girls with CPP performed brain magnetic resonance imag...

hrp0086p1-p894 | Thyroid P1 | ESPE2016

Comprehensive Analysis of Seven Toll-Like Receptor Genes Including 15 Single-Nucleotide Polymorphisms with Autoimmune Thyroid Disease in Korean Children

Cho Won Kyoung , Jang Jung-Pil , Ahn Moon Bae , Jung Min Ho , Kim Tai-Gyu , Suh Byung-Kyu , Kim Shin Hee , Cho Kyoung Soon , Park So Hyun

Background: The Toll-like receptors (TLRs) are germline-encoded receptors that play an essential role in initiating the immune response against pathogens.Objective and hypotheses: In this study, we assess the association of TLR polymorphism with autoimmune thyroid disease (AITD) in Korean children.Method: Seven Toll-like receptor genes (TLR-1, -2, -3, -4, -5, -6, -9) including 15 single-nucleotide polymor...

hrp0084p2-376 | Fat | ESPE2015

Metabolic Syndrome Components of Normal Weight Central Obese Adolescents in Korea Stratified by Waist-To-Height Ratio: Results from K-NHANES 2008–2010

Cho Won Kyoung , Lee Hyun Young , Ahn Moonbae , Jung In-Ah , Kim Shin Hee , Cho Kyoung Soon , Park So Hyun , Jung Min Ho , Suh Byung-Kyu

Background: A subset of central obese but normal weight individuals has been identified, who harbor potentially increased risks for development of MS despite a normal BMI.Objective and hypotheses: We try to evaluate metabolic syndrome (MS) components of normal weight central obese adolescents in Korea stratified by waist-to-height ratio (WHR).Method: This is a cross-sectional study. Data were obtained from the Korean National Healt...