hrp0092p2-218 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

The Difference of Body Mass Index (BMI) Score Before and After Gonadotropin-Releasing Hormone Agonist (GnRHa) Treatment in Central Precocious Puberty Girls

Choi Yujung , Lee Seonhwa , Kim Seulki , Ahn Moonbae , Kim Shinhee , Cho Wonkyoung , Cho Kyoungsoon , Jung Minho , Suh Byungkyu

Purpose: We investigated the difference of body mass index (BMI) score before and after gonadotropin-releasing hormone agonist (GnRHa) treatment in central precocious puberty girls (CPP).Methods: Medical records of 188 girls with CPP treated with GnRHa were reviewed. All patients completed the therapy. The patients were categorized into two groups according to initial BMI; normal weight group (BMI < 85 percentile) an...

hrp0092p1-233 | Growth and Syndromes (to include Turner Syndrome) (1) | ESPE2019

Growth Patterns Over Two Years After Birth According to the Birth Weight and Length Percentile in Children Born Preterm

Kim Seulki , Choi Yujung , Lee Seonhwa , Lee Yoonji , Lee Nayoung , Ahn Moonbae , Kim Shinhee , Cho Wonkyoung , Cho Kyoungsoon , Jung Minho , Suh Byungkyu

Purpose: This study aimed to analyze growth patterns during the first two years after birth according to the birth weight and length percentile in children born preterm, and to investigate factors affecting postnatal growth of these children.Methods: Eighty-two preterm neonates with a gestational age below 37 weeks who followed up until 24 months of corrected age (CA) were retrospectively reviewed. Length, weight and hea...

hrp0092p3-117 | Fat, Metabolism and Obesity | ESPE2019

Comparison of Different Criteria for the Definition of Insulin Resistance and Its Relation with Metabolic Risk in Overweight and Obese Adolescents

Lee Seonhwa , Choi Yujung , Kim Seulki , Lee Nayeong , Lee Yoonji , Ahn Moonbae , Kim Shinhee , Cho Wonkyoung , Cho Kyoungsoon , Jung Minho , Suh Byungkyu

This study aimed to compare cut-off points corrected for age and gender (CCOP) with fixed cut-off points (FCOP) for fasting plasma insulin and homeostasis model assessment-insulin resistance (HOMA-IR) for the diagnosis of IR in Korean obese children and adolescents and to identify IR applying CCOP and FCOP using as outcome the presence of dyslipidemia and Metabolic syndrome (MetS).We performed a cross sectional analysis of data from 195 adolescents aged ...

hrp0089p1-p063 | Diabetes &amp; Insulin P1 | ESPE2018

Glucose Intolerance in Survivors of Childhood Hematologic Disorders

Lee Seonhwa , Choi Yujung , Kim Seul ki , Ahn Moonbae , Chun Min-Kyo , Kim Shinhee , Cho Wonkyoung , Cho Kyoungsoon , Jung Minho , Suh Byungkyu

Purpose: To investigate overall characteristics of glucose intolerance in childhood survivors of hematologic diseases and suggest risk factors which increase A1c (glycated hemoglobin) level.Methods: Based on a retrospective review of 394 children who were diagnosed with acute leukemia or aplastic anemia between 2015 and 2016 under the age of 15, glucose intolerance was observed in 14 patients. A definition of glucose intolerance was A1c above 5.7%. Auxol...

hrp0089p2-p412 | Thyroid P2 | ESPE2018

Thyroid Function in the Korean Obese Children and Adolescents: Korea National Health and Nutrition Examination Survey 2013 to 2015

An Youngmin , Eun Lee Ji , Ju Suh Young

Purpose: In recent years, there has been an increasing focus on thyroid function in pediatric obese patients, but no nationwide study evaluating the relationship between thyroid function and obesity has yet been conducted in Korea. We aimed to evaluate thyroid dysfunction in obese Korean children.Methods: We analyzed the association between obesity and thyroid hormone levels among 975 Korean boys and girls aged 10–18 years, who participated in the K...

hrp0092fc8.6 | Pituitary, Neuroendocrinology and Puberty Session 1 | ESPE2019

Source and Changes in Serum Level of Kisspeptin in Female Rats at Different Developmental Stages

Kwon Ahreum , Kim Ho-seong , Suh Jungwhan , Choi Han-saem , Song Kyungchul , Suh Yongsuk

Introduction: The Kiss1/Kisspeptin/Kiss1r system is essential for puberty onset and reproductive system development, especially in the hypothalamus. Nevertheless, Kiss1 is expressed in other organs. Additionally, serum kisspeptin has been associated with puberty. However, studies on the developmental changes in serum kisspeptin levels and its main source are limited. Therefore, the aim of this study was to evaluate the developmental ...

hrp0092p3-174 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

Population Prevalence of Down's Syndrome and Cardiac Complications in South Korea: Based on National Health Insurance Service (NHIS)

Lee Na yeong , Cho Won Kyoung , Suh Byun-Kyu

Backgrounds: There is a no reliable population-based prevalence data of Down's syndrome (DS) in South Korea. In the present study, we try to estimate the incidence and prevalence of DS and cardiac complications in South Korea using data of National Health Insurance Service (NHIS) data and Rare Diseases Registry.Methods: We collected the data on DS patients who registered in the Rare Diseases Registry (RDR) between 20...

hrp0089p3-p202 | GH &amp; IGFs P3 | ESPE2018

Final Adult Height After Growth Hormone Treatment in Patients with Turner Syndrome

Ahn Jungmin , Suh Junghwan , Kim Hoseong , Kwon Ahreum

This study aimed to evaluate final adult height after recombinant growth hormone (GH) treatment in girls with Turner syndrome (TS) and elucidate the contributing factors to growth response. (Seventy-four patients with Turner syndrome who were treated with GH and reached adult height and 18 patients without treatment were enrolled in this study. To determine final height gain, we assessed the difference between the final height standard deviation score (SDS) and height SDS at t...

hrp0092p2-122 | Fat, Metabolism and Obesity | ESPE2019

Insulin-like Growth Factor-1 and Binding Protein-3 in Children with Metabolic Syndrome

Lee yoonji , Ahn Moonbae , Kim Seulki , Choi yujung , Cho Wonkyung , Jung Minho , Suh Byung-Kyu

Purpose: To examine the association of Insulin-like growth factor-1 (IGF-1) and binding protein-3 (IGFBP-3) with metabolic parameters of childhood obesity and assess its relationship with the presence of metabolic syndrome (MetS)Methods: A cross-sectional study of total 307 children and adolescents referred for growth assessment was performed. Subjects were divided into three groups based on body mass index (BMI) percent...

hrp0092p2-166 | GH and IGFs | ESPE2019

Prediction of the First-Year Response to Growth Hormone Treatment in Prepubertal Korean Children with Idiopathic Growth Hormone Deficiency: Analysis of Data from the LG Growth Study Database

Cho Wonkyoung , Ahn Moon-Bae , Cho Kyoung Soon , Jung Min Ho , Suh Byung-Kyu

Background: Insufficient data exist for the prediction of the first-year response to growth hormone (GH) treatment in Korean prepubertal children with idiopathic GH deficiency (GHD).Methods: Data from children (n = 345) who were in the LG Growth Study Database or had participated in other relevant clinical trials were used to develop a model. All included patients had been diagnosed with idiopathic GHD with maximum G...