hrp0092p1-117 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

The Role of Rat Hypothalamus Kisspeptin, Neurokinin and their respective Receptors in the Prolactin-Infertility Interaction

Isik Eylul Akbal , USLU Inayet Nur , AY Gulsevinc , CETINEL Nesrin , COMERTPAY Gamze , OKSUZ Hale , BARC Deniz , AKILLIOGLU Kubra , TOPALOGLU Ali Kemal , YILMAZ Mehmet Bertan

Aim: In this study, we investigated whether there was a relationship between prolactin hormone (PRL), whose excess levels lead to infertility, and expression of Kisspeptin (Kiss1), Neurokinin (Tac2) and their respective Receptors.Material and Methods: In our study, 12-16 weeks old 40 female Wistar Albino rats were classified into three groups; control group (n=10), physiological saline (SF) (n=1...

hrp0089p2-p049 | Bone, Growth Plate & Mineral Metabolism P2 | ESPE2018

Pediatric Quality of Life Inventory in Children with Osteogenesis Imperfect in Dr Soetomo Hospital Surabaya

Rochmah Nur , Faizi Muhammad

Osteogenesis imperfecta is a heritable systemic disorder of bone and connective tissue. Acceptance of children and their family is associated with medical, growth, developmental conflicts, physical, social and emotional. The study about impact of OI in children’s quality of life is still limited. Aims is to analyze PedsQL score in OI children in Dr. Soetomo Hospital, Surabaya.Methode: This study is a cross sectional study held in pediatric endocrine...

hrp0089p3-p113 | Diabetes & Insulin P3 | ESPE2018

Fructosamine Level in Type 1 Diabetes Mellitus Children Performing Ramadhan Fasting

Faizi Muhammad , Rochmah Nur

Background: Ramadan fasting may influence metabolic control in Type 1 Diabetes Mellitus. Fructosamine is an accurate metabolic control in a short-term period. Comparison of fructosamine between intensive and conventional insulin regimen in T1DM children has not been widely studied.Objective: To compare fructosamine level between intensive and conventional insulin regimens during Ramadan Fasting in T1DM.Methods: Observational analyt...

hrp0089p3-p115 | Diabetes & Insulin P3 | ESPE2018

Association between Thyroid Stimulating Hormone and Hemoglobine A1c in Type 1 Diabetes Mellitus Children

Rochmah Nur , Faizi Muhammad

Background: Type 1 Diabetes Mellitus children are at risk to suffer from thyroid dysfunction. The association between thyroid stimulating hormone and hemoglobin A1c is still controversy.Objective: To determine the association between thyroid stimulating hormone and hemoglobin A1c in type 1 Diabetes Mellitus children.Methods: We conducted a cross sectional study from January - June 2017 in pediatric endocrine outpatient clinic dr So...

hrp0089p3-p116 | Diabetes & Insulin P3 | ESPE2018

Monogenic Diabetes in 2 Years and 4 Months Old Girl: Is it DEND?

Rochmah Nur , Faizi Muhammad , Purwana Arie

Background: Monogenic forms of diabetes are still rare and not well understood. Their prevalence accounting for 1–4% of pediatric diabetes cases. Several genes encoding proteins important to β-cell function or regulation have been identified that lead to monogenic diabetes. However, awareness of these conditions may be lacking, and screening for them genetically is not routinely undertaken due to lack facility.Objective: To report a case diagno...

hrp0089p2-p163 | Fat, Metabolism and Obesity P2 | ESPE2018

Evaluation of Voiding Dysfunction in Obese Children

Nur Asilturk Havva , Ozhan Bayram , Yuksel Selcuk

Obesity is a common public health problem. Secondary complications are increasing with the increase in the prevalence of obesity. Studies on the effect of obesity on the urinary system in children continue and are limited. In this study, it was aimed to evaluate the relationship between childhood obesity and lower urinary tract dysfunction (LUTD) with metabolic and anthropometric measures. 400 obese children between 6 and 18 years of age who had a body mass index ≥95 per...

hrp0089p3-p300 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

Evaluation of Cases with Pubertal Gynecomastia

Nur Peltek Kendirci Havva , Demir Emre

Introduction and Aim: Pubertal gynecomastia is the transient proliferation of glandular tissue in breasts of men without any endocrin pathology. Relatively higher levels of estrogen than plasma testosteron levels and imbalance between tissue estrogen and testosteron levels are considered to be important in pathogenesis. In this study it is aimed to determine the clinical and laboratory properties of our patients who were diagnosed as pubertal gynecomastia and compare with heal...

hrp0089p3-p314 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

Klinefelter Syndrome with Ambiguous Genitalia in a Child

Faizi Muhammad , Rochmah Nur , Purwana Arie

Background: Klinefelter Syndrome (KS) is the most common sex chromosome disorder in males caused by additional X chromosome. It is characterized by progressive testicular failure. KS patient usually have complete male sexual differentiation without genital ambiguity. The prevalence of KS is 1 in 660 males which only 10% are detected before or during puberty, and about two third so fall men with X-chromosome polyploidies fail to be identified during their lifetime.<p class=...

hrp0084p3-1127 | Pituitary | ESPE2015

Pituitary Stalk Interruption Syndrome: A Case of an Infant

Kendirci Havva Nur Peltek , Kaya Zafer

Background: Pituitary Stalk Interruption Syndrome (PSIS) is a rare congenital abnormality of the pituitary that is responsible for anterior pituitary deficiency. It is characterized by a classic triad of interrupted pituitary stalk, absent or ectopic posterior pituitary, and anterior pituitary hypoplasia or aplasia. Hypothalamic hypothyroidism, hyperprolactinemia and deficiency of anterior pituitary hormones are typical characteristics. Clinical presentation varies according t...

hrp0094p2-373 | Pituitary, neuroendocrinology and puberty | ESPE2021

Evaluation of Clinical, Laboratory and Radiological Findings in the Differential Diagnosis of Premature Telarche and Central Puberty Precocious

Nur Peltek Kendirci Havva , Kaba İlknur ,

Introduction and Aim: Central puberty precocious (CPP) is defined as the development of secondary sex characters due to the activation of the hypothalamus-pituitary-gonad axis before the age of eight in girls. Premature telarche (PT) is defined as isolated breast development in girls without other findings of puberty. We aimed to evaluate the clinical, laboratory and radiological findings used in the differential diagnosis of PT and CPP....