hrp0082p2-d3-555 | Puberty and Neuroendocrinology (2) | ESPE2014

Tamoxifen-Induced Hirsutism: an Unusual Side Effect in a 5 Years Old Girl with Mccune–Albright Syndrome

Kirmizibekmez Heves , Mutlu Rahime Gul Yesiltepe , Dursun Fatma , Isguven Sukriye Pinar

Background: McCune–Albright syndrome is a rare disorder defined as the triad of peripheral precocious puberty, café-au-lait skin pigmentation and fibrous dysplasia of bone, caused by mutation of the gene GNAS1, resulting in autonomous endocrine hormone excess.Objective and hypotheses: This is the first pediatric case of hirsutism due to tamoxifen, a selective estrogen receptor modulator.Case report: A 53/12 yea...