ESPE Abstracts (2019) 92 P1-132

What is the Recurrence Rate of Benign Ovarian Tumors in Childhood? Ovarian Benign Organic Tumors (OBT) are a Rare Pathology in Childhood that Require Conservative Surgery with an Unknown Risk of Recurrence

Nina Detho1, Audrey Cartault1, olivier Abbo2, sofia Mouttalib2,1, Catherine Pienkowski1


1Reference Center for Rare Gynecologic Diseases, Toulouse, France. 2Department of Pediatric Surgery, Children's Hospital, Toulouse, France


Aim: The aim of the study was to predict the risk of tumor recurrence in OBT

Material and Methods: We conducted a retrospective, observational study (2001-2018) on the management of OBT in girls aged 0 to 18 at Toulouse University Hospital, France.

Results: 68 patients were included. 16% were prepubertal. Mean age was 11.35 ± 3.08 years. Pain was the main symptom in 49% of patients. 10 patients (mainly prepubertal) had acute ovarian torsion. The diagnosis was confirmed in all cases by pelvic ultrasound showing ovarian tumor and negative tumor markers. The evaluation was completed in 68 % of cases by MRI or CT.

Tumorectomy was performed in 70.6% of cases (48/68) and oophorectomy in 29.4%. Oophorectomy was more frequent in solid masses than in cystic masses: 36.96% (17/46) versus 10% (2/20), P = 0.026.

Laparoscopic surgery was performed in 28% of cases.

There were 62% germ cell tumors and 38% epithelial tumors.

Mean postoperative follow-up was 3.4 ± 2.6 years with 7 visits.

10.3% of patients (n = 7) had a recurrence on average 17 months (range 2 to 43 months). The solid ultrasound appearance and the bilaterality appeared to increase the risk of recurrence but no predictive factor was found. Puberty progression was age-appropriate for 97% of patients.

Conclusion: In our series, the recurrence rate after the first OBT is evaluated at 10%.The monitoring for at least 3 years is therefore essential with a pelvic ultrasound every six months.

New prospective and multicenter studies, as well as the creation of a register of rare benign ovarian tumors in childhood, are necessary to improve the follow-up of these patients.

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