ESPE Abstracts (2019) 92 P1-132

ESPE2019 Poster Category 1 Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology (22 abstracts)

What is the Recurrence Rate of Benign Ovarian Tumors in Childhood? Ovarian Benign Organic Tumors (OBT) are a Rare Pathology in Childhood that Require Conservative Surgery with an Unknown Risk of Recurrence

Nina Detho 1 , Audrey Cartault 1 , olivier Abbo 2 , sofia Mouttalib 2,1 & Catherine Pienkowski 1

1Reference Center for Rare Gynecologic Diseases, Toulouse, France. 2Department of Pediatric Surgery, Children's Hospital, Toulouse, France

Aim: The aim of the study was to predict the risk of tumor recurrence in OBT

Material and Methods: We conducted a retrospective, observational study (2001-2018) on the management of OBT in girls aged 0 to 18 at Toulouse University Hospital, France.

Results: 68 patients were included. 16% were prepubertal. Mean age was 11.35 ± 3.08 years. Pain was the main symptom in 49% of patients. 10 patients (mainly prepubertal) had acute ovarian torsion. The diagnosis was confirmed in all cases by pelvic ultrasound showing ovarian tumor and negative tumor markers. The evaluation was completed in 68 % of cases by MRI or CT.

Tumorectomy was performed in 70.6% of cases (48/68) and oophorectomy in 29.4%. Oophorectomy was more frequent in solid masses than in cystic masses: 36.96% (17/46) versus 10% (2/20), P = 0.026.

Laparoscopic surgery was performed in 28% of cases.

There were 62% germ cell tumors and 38% epithelial tumors.

Mean postoperative follow-up was 3.4 ± 2.6 years with 7 visits.

10.3% of patients (n = 7) had a recurrence on average 17 months (range 2 to 43 months). The solid ultrasound appearance and the bilaterality appeared to increase the risk of recurrence but no predictive factor was found. Puberty progression was age-appropriate for 97% of patients.

Conclusion: In our series, the recurrence rate after the first OBT is evaluated at 10%.The monitoring for at least 3 years is therefore essential with a pelvic ultrasound every six months.

New prospective and multicenter studies, as well as the creation of a register of rare benign ovarian tumors in childhood, are necessary to improve the follow-up of these patients.

Volume 92

58th Annual ESPE

Vienna, Austria
19 Sep 2019 - 21 Sep 2019

European Society for Paediatric Endocrinology 

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