Aim: The aim of the study was to predict the risk of tumor recurrence in OBT
Material and Methods: We conducted a retrospective, observational study (2001-2018) on the management of OBT in girls aged 0 to 18 at Toulouse University Hospital, France.
Results: 68 patients were included. 16% were prepubertal. Mean age was 11.35 ± 3.08 years. Pain was the main symptom in 49% of patients. 10 patients (mainly prepubertal) had acute ovarian torsion. The diagnosis was confirmed in all cases by pelvic ultrasound showing ovarian tumor and negative tumor markers. The evaluation was completed in 68 % of cases by MRI or CT.
Tumorectomy was performed in 70.6% of cases (48/68) and oophorectomy in 29.4%. Oophorectomy was more frequent in solid masses than in cystic masses: 36.96% (17/46) versus 10% (2/20), P = 0.026.
Laparoscopic surgery was performed in 28% of cases.
There were 62% germ cell tumors and 38% epithelial tumors.
Mean postoperative follow-up was 3.4 ± 2.6 years with 7 visits.
10.3% of patients (n = 7) had a recurrence on average 17 months (range 2 to 43 months). The solid ultrasound appearance and the bilaterality appeared to increase the risk of recurrence but no predictive factor was found. Puberty progression was age-appropriate for 97% of patients.
Conclusion: In our series, the recurrence rate after the first OBT is evaluated at 10%.The monitoring for at least 3 years is therefore essential with a pelvic ultrasound every six months.
New prospective and multicenter studies, as well as the creation of a register of rare benign ovarian tumors in childhood, are necessary to improve the follow-up of these patients.
19 - 21 Sep 2019
European Society for Paediatric Endocrinology