Volume 82 | ESPE2014 | Next issue

ESPE 2014

Dublin, Ireland
18 Sep 2014 - 20 Sep 2014

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Dublin, Ireland; 18-20 September 2014. Further information

Poster Category 3

Diabetes (2)

hrp0082p3-d3-724 | Diabetes (2) | ESPE2014

Prevalence of Impaired Glucose Tolerance and Insulin Resistance in a Sample of the 6- to 16-Year-Old Overweight or Obese Pediatric Population

Saffari Fatemeh , Vandaei Mahmood , Oveisi Sonia , Esmailzadehha Neda

Background: Prevalence of obesity and its complications including type 2 diabetes mellitus, impaired glucose tolerance and insulin resistance have been increased among children and adolescents during recent decades.Objective and hypotheses: The aim of this study was to determine the prevalence of impaired glucose tolerance and insulin resistance among overweight or obese children and adolescents.Method: This cross sectional study w...

hrp0082p3-d3-725 | Diabetes (2) | ESPE2014

Differences in Pubertal Development and Anthropometry Between Normal Population and Type 1 Diabetic Child at Debut in Spain

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Sanchez-Antonio Sonia , Lorente-Blazquez Isabel

Background: The deterioration caused DMtipo1 anthropometric and pubertal development. With intensive treatment, improved HbA1c and less microvascular complications should be similar to normal population.Objective: To study the pubertal development in our population with DM1 and final somatometric variables reached in relation to the normal population.Material and methods: Retrospective study of DM1A debut from diagnosis to final he...

hrp0082p3-d3-726 | Diabetes (2) | ESPE2014

Effect of Vitamin D Treatment on Glucose and Insulin Metabolism, and Bone Turnover in Children with Symptomatic Vitamin D Deficiency

El-fakhri Nagla , McMillan Martin , McNeilly Jane , Ahmed S F , McDevitt Helen

Background: There are limited data in paediatric population on the association between vitamin D deficiency/treatment and glucose/insulin metabolism.Objective and hypotheses: This study aimed to investigate the effect of vitamin D therapy on glucose homeostasis, insulin resistance and bone turnover, in children with vitamin D deficiency.Method: 22 children aged 3 months to 10 years (nine male) who were diagnosed with vitamin D defi...

hrp0082p3-d3-727 | Diabetes (2) | ESPE2014

Evaluation of HbA1c Measurement in Trinidad and Tobago

Rastogi Maynika , Ladenson Paul , Goldstein David , Little Randie

Introduction: The prevalence of diabetes in Trinidad and Tobago (T&T) exceeds 12%. Monitoring of HbA1c is standard of care to assess diabetes control but assay reliability requires high precision and standardization to either DCCT or IFCC values and results should be monitored through proficiency testing (PT). In T&T a developing country there is no existing data on HbA1c precision and accuracy. Johns Hopkins Medicine International and the Diabetes Diagnostic Laborator...

hrp0082p3-d3-728 | Diabetes (2) | ESPE2014

The Result of Sulphonylureas Treatment in Patients with Neonatal Diabetes Mellitus due to kcnj11/abcc8 Gene Mutations in Vietnam

Bich Ngoc Can Thi , Chi Dung Vu , Phuong Thao Bui , Ngoc Khanh Nguyen , Phu Dat Nguyen , Ellard Sian , Craig Maria , Thi Hoan Nguyen

Background: Neonatal diabetes may be defined as hyperglycemia diagnosed within the first 6 months of life which is permanent neonatal diabetes or transient neonatal diabetes. They can result from some gene mutations such as KCNJ11, ABCC8, INS, GCK, … In there, the most common cause of neonatal diabetes mellitus is associated with activating mutations in the KCNJ11 gene, which encodes Kir6.2-a subunit of the ATP-sensitive potassium channel (KATP) of the β cell and AB...

hrp0082p3-d3-729 | Diabetes (2) | ESPE2014

Prevalence of Secondary Diabetes and Related Factors in China Hospitalized Children

Yu-Chuan Li , Bing-yan Cao , Chun-xiu Gong , Xue-jun Liang

Background: Secondary diabetes in children, often rising from the treatment of the primary disease. However, not enough attention has been paid. We analyze the cases of secondary diabetes in children identified from 2002 to 2010 in our hospital for the frequency and clinical features, so as to gain a better understanding of the disease.Objective and hypotheses: To investigate the prevalence and association factors of secondary diabetes in Chinese hospita...

hrp0082p3-d3-730 | Diabetes (2) | ESPE2014

Wolcott–Rallison Syndrome in Two Siblings with no Implication of EIF2AK3 Mutation

Altincik Ayca , Ozhan Bayram , Flanagan Sarah , Ellard Sian

Background: Wolcott–Rallison syndrome (WRS) which is characterized with permanent neonatal diabetes mellitus (PNDM), epiphyseal dysplasia, recurrent hepatitis and is caused by EIF2AK3 mutations.Objective and hypotheses: There is a possibility of a variant form of WRS, not caused by EIF2AK3 mutation.Method: Case 1: She was born at term from consanguineous parents. Family history was unremarkable. She had been ...

hrp0082p3-d3-731 | Diabetes (2) | ESPE2014

Prevalence of Atopic Diseases in Diabetic Children and Adolescents

Jasser-Nitsche Hildegard , Varga Eva-Maria , Frohlich-Reiterer Elke , Hontzsch Julia , Pieringer Lisa , Avian Alexander , Borkenstein Martin

Background: In the last decade, an increase in the incidence of type 1 diabetes mellitus (T1D) has been observed worldwide, as well as an increase in the incidence of allergies in childhood. Both diseases are characterized by an imbalance between Th1- and Th2 cells. Autoimmune disorders are considered to be associated with a Th1 immune response while allergic diseases with a Th2 response. However, studies conducted to find a correlation between T1D and atopic diseases are hete...

hrp0082p3-d3-732 | Diabetes (2) | ESPE2014

The Pattern of Body Composition Change in Type 1 Diabetes by Gender

Kim Yong Hyuk , Park Hye Won , Kim Kyo Sun , Chung Sochung

Background: Childhood period is associated with growth accompanied by rapid change of body composition. Excessive fat gain and followed increased insulin resistance is an obstacle in controlling blood sugar for type 1 diabetic patients.Objective and hypotheses: This study was designed to understand the gender difference in the patterns of body composition change along the growth process of newly diagnosed type I diabetic children and adolescents.<p c...

hrp0082p3-d3-733 | Diabetes (2) | ESPE2014

Transient Neonatal Diabetes and Intermediate DEND Phenotype with KCNJ11 Mutation

Fitas Ana Laura , Morais Rita Belo , Viveiros Eulalia , Simoes Anabela , Raposo Ana , Anselmo Joao , Limbert Catarina , Lopes Lurdes

Background: Neonatal diabetes (ND) is a rare condition (1:160.000-260.000 live births) associated with diabetes onset within the first 6 months of life. It can be permanent (PNDM) or transient (TNDM), and several genes can be implicated in both, namely KCNJ11. Clinical phenotypes usually correlate to the causal gene. KCNJ11 mutations are usually associated with PNDM whilst the most frequent cause of TNDM is disordered imprinting in the 6q24 locus.Objecti...

hrp0082p3-d3-734 | Diabetes (2) | ESPE2014

Offspring of Parents with Obesity, Complex Investigations Risk of Carbohydrate Disturbances and Diabetes

Wasik Renata , Dziura Maria , Basiak Aleksander

Aim: To examine offspring of patients with simple obesity. To ascertain, if there are some disturbances in the carbohydrate or lipid metabolism or unknown type 2 diabetes in these subjects.Method and subjects: Examined were 132 families, 108 families with obesity, and 24 families without obesity, the control group. 14 additional were excluded because of ascertained at the time of examination unknown type 2 diabetes in the parents. In all of the offspring...

hrp0082p3-d3-735 | Diabetes (2) | ESPE2014

Metabolic Control in a Pediatric Population with Type 1 Diabetes Mellitus

Andrade Joana , Gomes Clara , Luis Assuncao , Laranjo Gabriela , Campos Joana

Background: Type 1 diabetes mellitus (T1DM) is one of the most frequent chronic diseases in childhood and adolescence. Poor metabolic control is associated with numerous and onerous consequences. HbA1c levels are important in the assessment and monitoring of metabolic control in T1DM. Therefore, it is essential to know the causes of its variability.Objective and hypotheses: Determine the impact of age and time of disease in the value of HbA1c in children...