ESPE2014 Poster Category 3 Fat Metabolism & Obesity (2) (13 abstracts)
Prevalence of Abnormalities of Glucose Metabolism in Obese Greek Children and Adolescents
Feneli Karachaliou a , Irene Kaloumenou a , Elpis-Athina Vlachopapadopoulou a , Paraskeui Katsixti a , Aspasia Fotinou b & Stefanos Michalacos a
aEndocrinology-Growth and Development Department, ‘P & A Kyriakou’ Children’s Hospital, Athens, Greece; b’P & A Kyriakou’ Children’s Hospital, Microbiology, Athens, Greece
Background: Obesity is associated with alterations in glucose metabolism, often present from childhood.
Objective and hypotheses: To assess the prevalence of glucose metabolism alterations and insulin resistance in a group of obese, otherwise healthy children and adolescents from Greece.
Method: It is a retrospective study of 130 obese children and adolescents, 79 girls (61%), aged 5.4 to 15.2 years (mean±S.D.: 10.8±2.1). Obesity was defined according to IOTF criteria. All subjects underwent an oral glucose tolerance test (OGTT). Fasting insulin, HOMA index and insulin values on OGTT were used as indexes of insulin resistance.
Results: No case with impaired fasting glucose was detected. Impaired glucose tolerance was observed in 15.5% of subjects. Only one boy aged 13.5 years had diabetes type 2. Insulin resistance was found in 29% of subjects by the use of HOMA index and in 48% by the insulin response in OGTT.
Conclusion: Disturbances in glucose metabolism are present in a considerable number of young subjects and insulin resistance is the earlier abnormality in glucose homoestasis. This emphasizes the usefulness of OGTT as a screening tool for identification of subjects with small disturbances of glucose metabolism and prevention of type 2 diabetes through intensive intervention.
Article tools
My recent searches
My recently viewed abstracts
ESPE Abstracts
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more