ESPE2014 Poster Category 2 Fat Metabolism & Obesity (2) (23 abstracts)
aDepartment of Pediatrics, The Childrens Obesity Clinic, Copenhagen University Hospital Holbæk, Holbæk, Denmark; bThe Novo Nordisk foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Copenhagen, Denmark; cDepartment of Public Health, Core Biostatistics, University of Copenhagen, Copenhagen, Denmark
Background: Childhood obesity and related co-morbidities are increasing world wide and consequently effective treatment interventions are much needed.
Objective and hypotheses: The aim was to investigate concomitant changes in body composition in relation to changes in BMISDS during The Childrens Obesity Clinics Treatment (TCOCT) program. Hypothesis: reductions in body fat percentage may not be revealed by reductions in BMISDS.
Method: One-hundred-ninety- three (108 girls) children and youths with a median age of 12.4 years (range 6.222.7) were examined by height, weight, and dual-energy X-ray absorptiometry (DXA scan) at baseline and after 1 year of multidisciplinary childhood obesity treatment.
Results: At the baseline the participants had a median BMISDS of 2.8 (range 1.54.9) and a median percent body fat (%BF) of 43.6% (range 28.957.1). Of the 193 children and youths, 57% reduced their BMISDS, 30% had a stable BMISDS (ΔBMISDS ±0.15), and 13% increased their BMISDS during treatment. The group reducing their BMISDS (n=110) decreased their %BF by −4.0% (95% CI: (−4.8; −3.3), P<0.0001). The group with a stable BMISDS (n=58) tended to decrease their %BF by −0.5% (95% CI: (−1.1; 0.2), P=0.15), and the group increasing their BMISDS (n=25) increased their %BF by 1.6% (95% CI: (0.1; 3.1), P=0.04). Reductions in BMISDS were positively correlated to reductions in %BF (P<0.0001).
Conclusion: During multidisciplinary treatment of childhood obesity, a reduction in %BF may be possible even in children exhibiting a stable BMISDS indicating a favorable treatment response in a larger percentage of children treated.