Background: Children with different growth disorders need therapy with recombinant human GH. Although mostly therapy leads to good results there are clinical cases when the therapy is not working. One of the reasons is patients and patients familys adherence. Thats why it is necessary to explore what are the adherence and its impact on therapys outcome. Growth disorders can make an influence to all humans life, thats why if it is possible to do something to change it must be done. It is necessary to explore the situation in Latvia so that we can make conclusions and recommendations how to improve the situation.
Objective and hypotheses: There is hypothesis to prove that children in Latvia with GH therapy have bad adherence and it impacts the therapys outcome.
Method: Research is still going on. It is retrospectiveprospective research. Literature of the last 510 years has been analysed. Statistical analysis is made with material that is taken from Children Clinical University Hospital ambulatory cards after special questionnaire. Patients aged 018 years are included, who are on GH treatment on years 20132014 and uses Easypod device.
Results: As the research continues, the final results will follow.
Conclusion: Already from the first results we can conclude, that adherence to the treatment with Easypod device is quite well. We can also see that pubertal children have worse adherence than smaller children, because in pubertal period parents dont have so big influence on therapy and the therapy is more superficially done. The research must be continued to see if in Latvian population computerized and controlled therapy really gives better results.
20 - 22 Sep 2014
European Society for Paediatric Endocrinology