Scope: The assessment of the functional ovarian maturity in a group of girls with precipitated puberty.
Method: Ovarian function was assessed in a group of girls with puberty precipitated (77 group 1) compared with a group of girls with normal puberty (59 group 2) according to development criteria accepted by the population of Romania. They calculated the incidence of menstrual disorders, changes in menstrual flow, presence of dysmenorrhoea or premenstrual syndrome, breast development, serum levels of ovarian hormones, the incidence of ovarian cysts.
Results: The existence of menstrual disturbances (66.1% group 1 and 34% group 2), duration of the menses (66.6% group 1 and 33.3% group 2); the quantity of the menstrual flux altered (61.3% group 1 and 36.8% group 2), the presence of dysmenorrhea and/or premenstrual syndrome (60.4% group 1 and 39.6% group 2), end-stage of breast development (24.7% group 1 and 75.3% group 2), the presence of low blood levels of ovarian hormone (81.4% group 1 and 18.6% group 2), presence of ovarian cysts (64% group 1 and 36% group 2).
Conclusions: These observations reveal disorders of the sexualization process on girls with precipitate puberty on the grounds of a delayed functional ovarian maturity (P<0.001) compared with girls with normal puberty.
20 - 22 Sep 2014
European Society for Paediatric Endocrinology