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54th Annual ESPE

Barcelona, Spain
01 Oct 2015 - 03 Oct 2015

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Barcelona, Spain; 1-3 October 2015 Further information

Poster Category 2


hrp0084p2-496 | Perinatal | ESPE2015

Serial 3-Dimensional Ultrasonographic Evaluation of Foetal Adrenal Volumes in the 2nd and 3rd Trimester of Pregnancy Characterises Human Adrenal Development in utero

Baftic Nerma , Katugampola Harshini , Meso Muriel , Allen Rebecca , Marleen Shemoon , Elahi Shezan , Aquilina Joe , Dunkel Leo , Storr Helen

Background: The human foetal adrenal (FA) undergoes vast physiological changes as pregnancy progresses. Original descriptions of FA development emerged following morphometric studies from spontaneous/medical terminations. These revealed the greatest increase in FA size was during the first trimester. Recently, sonographic evaluation of human FA volume and length has led to the creation of normal FA growth centiles and correlations between FA size and estimated foetal weight (E...

hrp0084p2-497 | Perinatal | ESPE2015

Genetic Variation in the FSH Signalling Pathway Affects Female Reproductive Hormones During Infancy

Henriksen Louise S , Hagen Casper P , Assens Maria , Almstrup Kristian , Main Katharina M

Background: Studies have shown that genetic variations in the FSH pathway (SNPs: FSHB −211G>T, FSHR −29G>A, and FSHR 2039A>G) affect peripubertal levels of serum FSH and age at pubertal onset in girls.Objective and hypotheses: Genetic variations in the FSH pathway reflect circulating levels of female reproductive hormones during the postnatal gonadotropin surge.Method: Blood samples were taken in girls of th...

hrp0084p2-498 | Perinatal | ESPE2015

Longitudinal Comparison of Inhibin B and AMH Levels and Testicular Volumes between Preterm and Full-Term Infant Boys

Kuiri-Hanninen Tanja , Seuri Raija , Tyrvainen Erja , Dunkel Leo , Sankilampi Ulla

Background: Decreased reproductive rates have been reported in men born prematurely. This potentially relates to an impaired Sertoli cell proliferation during the postnatal hypothalamic-pituitary-gonadal activity, which has been suggested to have a role in later reproductive capacity.Objective and hypotheses: To compare the levels of Sertoli cell markers in premature (PT) and full-term (FT) boys in infancy.Method: Serum AMH and inh...

hrp0084p2-499 | Perinatal | ESPE2015

Postnatal Catch-Down Growth is not Associated with Disturbances in Metabolic Parameters in Large-for-Gestational-Age Infants at the Age of 8 Years

Peters Julia , Woelfle Joachim , Joergens Susanne , Bartmann Peter , Gohlke Bettina

Background: Children born small-for-gestational-age (SGA) especially when they experience rapid catch-up growth have an increased risk for obesity and metabolic disturbances later in life.Aims and objectives: Little is known about the effect of catch-down (c-d) growth and its effect on metabolic parameters in children born large-for-gestational-age (LGA).Patients and methods: 101 pre-pubertal children with a birth-weight and/or len...

hrp0084p2-500 | Perinatal | ESPE2015

Birth Incidence of Prader-Willi Syndrome in France

Bar Celine , Diene Gwenaelle , Molinas Catherine , Casper Charlotte , Tauber Maithe

Background: Prader-Willi syndrome (PWS) is a rare and complex genetic disorder characterised in neonates by hypotonia and feeding problems. French birth incidence has never been reported.Objective and hypotheses: To evaluate incidence of PWS at birth in France.Method: Identification of patients with a molecular diagnosis of PWS born between January 1st, 2013 and December 31st, 2013 was obtained by combining va...

hrp0084p2-501 | Perinatal | ESPE2015

Variation of Environmental Chemicals Measured in Serum During Pregnancy

Assens Maria , Frederiksen Hanne , Juul Anders , Main Katharina

Background: Significant changes in metabolism and water equilibrium are registered during pregnancy. However, very limited previous investigations have been carried out on variations of exposure levels and metabolism of non-persistent environmental chemicals during pregnancy.Objective and hypotheses: The objective of this longitudinal study is to describe variation in exposure of pregnant women to environmental chemicals. We hypothesise that variation in...

hrp0084p2-502 | Perinatal | ESPE2015

Auxological Parameters, Endocrine Growth Factors and Insulin Resistance from Birth to 12 Months of Life in Children Born Small for Gestational Age

Guazzarotti Laura , Mauri Silvia , Occhipinti Federica , Petruzzi Mariangela , Sonnino Micol , Tenconi Andrea Angela , Pogliani Laura , Zuccotti Gian Vincenzo

Background: At present, literature regarding postnatal growth in small for gestational age (SGA) subjects and its’ correlation with growth factor levels is still controversial. A relation between IGF1 and IGFBP3 levels at birth and weight and length catch up growth has been demonstrated. In the first months of life a rapid weight catch-up growth has also been associated to an increase of leptin, basal insulin and insulin resistance.Objective and hyp...

hrp0084p2-503 | Perinatal | ESPE2015

Serum Fetuin-a Level for Diagnosis Hepatic Steatosis in Children with Type 1 Diabetes Mellitus

Kurtoglu Selim , Dogan Murat , Hatipoglu Nihal , Muhtaroglu Sebahattin , Doganay Selim , Gul Ulku , Elmali Ferhan

Backgound: Type 1 diabetes mellitus (T1DM) is one of the chronic disease frequently encountered in childhood and the non-alcoholic fatty liver disease is one of the uncommon complications in the management of these patients.Objective and hypotheses: In this study, we aimed to investigate the relationship between serum fetuin-A levels which a negative acute phase reactant and the non-alcoholic fatty liver disease in T1 diabetic patients.<p class="abst...

hrp0084p2-504 | Perinatal | ESPE2015

Association of Dll4 Levels and VEGFR-1, VEGFR-2 in Mice Model of Oxygen-Induced Retinopathy

Liu Wangkai , Su Yihua , Zhuang Siqi , Li Xiaoyu , Li Yijuan

Background: Notch1 – Delta-like ligand 4 (Dll4) signaling pathway has a biological effect of negative feedback regulation to VEGF in retinal vascular development process. There are few studies on the inhibition of Notch1-Dll4 signaling pathway in ROP and the regulatory pathway of VEGF.Objective and hypotheses: 67-day-old mice were divided into oxygen-induced retinopathy group and control group. We took ten mice from each group at postnatal day 7 (p7...

hrp0084p2-505 | Perinatal | ESPE2015

Evaluation of Thyroid Function in Preterm Newborns of 24–30 Weeks of Gestation

Ariadna Campos-Martorell , Maria Clemente , Diego Yeste , Felix Castillo , Maria Narvaez Karla , Antonio Carrascosa

Background: Preterm newborns due to their immaturity, a higher incidence of mortality and increased susceptibility to iodine, are at risk of decreased thyroid function. Low levels of thyroid hormones during a critical period for the development of the central nervous system may negatively affect their psychomotor development. Screening for congenital hypothyroidism with capillary TSH is invalid for preterm babies and would require an specific thyroid function control.<p cl...

hrp0084p2-506 | Perinatal | ESPE2015

Mini-Puberty in Boys with Cryptorchidism

Raygorodskaya Nadezda , Bolotova Nina

Background: The period of transitory postnatal activation of the hypothalamo-pitutary-gonadal axis (mini-puberty) plays an important role in the testicular maturation.Objective and hypotheses: To evaluate the functional condition of the gonads in 1–3 months boys with cryptorchidism.Method: 40 boys ages 1–3 months with cryptorchidism were examined: group 1–30 boys with unilateral inguinal retention testis and group 2&...