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54th Annual ESPE

Barcelona, Spain
01 Oct 2015 - 03 Oct 2015

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Barcelona, Spain; 1-3 October 2015 Further information

hrp0084p3-828 | Fat | ESPE2015

Long-Term Effects of a Ketogenic vs a Hypocaloric Diet in Children and Adolescents with Obesity

Partsalaki Ioanna , Karvela Alexia , Spiliotis Bessie E

Background: The prevalence of childhood obesity is high worldwide and predisposes to adult obesity and metabolic disorders. Many dietary approaches have been proposed to reduce this prevalence, but no single diet has proven to be superior to others in terms of long-term weight loss maintenance in children.Objective and hypotheses: To evaluate and compare long-term body weight changes among obese children and adolescents who had lost at least 10% of their...

hrp0084p3-829 | Fat | ESPE2015

Metabolically Unhealthy Obese Children Under the Risk of Exercise Induced Chronotropic Incompetence

Chaychenko Tetyana , Rybka Olena

Background: There is a high incidence of acute cardiovascular events in obese subjects.Objective and hypotheses: We hypothesised that exercise tolerance is different in metabolically healthy (MHO) and metabolically unhealthy (MUO) obese adolescents.Method: 45 obese adolescents aged 10–17 (23 males and 22 females) were examined with an anthropometry, fasting blood glucose, insulin and lipids. IDF criteria were used for grouping...

hrp0084p3-830 | Fat | ESPE2015

Determinants of Serum Interleukin 1 – Receptor Antagonist Concentrations in 12-Year-Old Children Born Small or Appropriate for Gestational Age

Seppa Satu , Voutilainen Raimo , Tenhola Sirpa

Background: Elevated concentrations of interleukin 1 – receptor antagonist (IL-1Ra) have been found in adult subjects with the metabolic syndrome and type 2 diabetes as a marker of inflammation.Objective and hypotheses: Our aim was to study whether serum IL-1Ra associates with markers of reduced insulin sensitivity (IS) and dyslipidemia in 12-year-old children.Method: A total of 192 children (109 girls) were studied at the mea...

hrp0084p3-831 | Fat | ESPE2015

Evaluation of Renal Functions in Obese Children and Adolescents with Cystatin-C and Creatinin Based GFR: is Increasing GFR Reflected Hyperfiltration and Possible Renal Damage in Future?

Salman Dilsah Onerli , Siklar Zeynep , Ilarslan Nisa Eda Cullas , Kocaay Pinar , Ozcakar Birsin , Berberoglu Merih

Introduction: There is a growing interest in the relationship between obesity and renal damage. Chronic kidney disease is accepted as an important complication of obesity in adulthood. However, information on association between childhood obesity and renal functions is limited. In this study, It is aimed to investigate the renal functions in obese children and adolescents.Patients and methods: We enrolled 107 obese children and adolescents as a study gro...

hrp0084p3-832 | Fat | ESPE2015

The French Experience in Bariatric Surgery ‘Laparoscopic Adjustable Gastric Banding’ in Adolescence

Dabbas Myriam , Khen-Dunlop Naziha , De Filippo Jean Paul , Bougneres Pierre , Goulet Olivier , Revillon Yann

Background: Because the success rate of lifestyle interventions is modest in severely obese adolescents, surgical treatments are now proposed. Laparoscopic adjustable gastric banding (LAGB) represents an attractive treatment with minimal morbidity and reversible procedure.Method: All adolescents were included in prospective longitudinal assessment and entirely managed by a pediatric team. Surgery was proposed only after at least 1-year lifestyle interven...

hrp0084p3-833 | Fat | ESPE2015

Correlation of Serum FGF-21 Levels with Metabolic Parameters in Korean Obese Children

Baek Joonwoo , Nam Hyo-Kyoung , Rhie Young-Jun , Lee Kee-Hyoung

Background: Serum FGF-21 levels are increased in adults with obesity, type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). Serum FGF-21 levels have been implicated as a potential biomarker for early detection of the metabolic syndrome (MetS) and type 2 diabetes in adults. However, there are only a few studies about the correlation between FGF-21 levels and metabolic parameters in children.Aims and objective: This study is aimed to evaluate the r...

hrp0084p3-834 | Fat | ESPE2015

Liver Steatosis in Obese Children Courses with Enhanced Insulin Resistance and Dyslipidaemia, Which are Influenced by Gender, Puberty, Race and Body Fat Distribution

Martos-Moreno Gabriel A , Martinez-Villanueva Julian , Gonzalez-Leal Rocio , Sirvent Sara , Minguez Arturo , Martinez Guillermo , Hawkins Federico G , Argente Jesus

Background: Liver steatosis (LS) is diagnosed in obesity at very early ages, not exclusively related to overweight severity.Objective and hypotheses: To investigate the features of patients diagnosed with obesity associated LS (ultrasonography).Method: We retrospectively studied 88 obese (BMI>+2 SDS) children with LS (LS-OB) and 88 age, gender, race and puberty matched obese children without LS (no-LS-OB). BMI-SDS, body composi...

hrp0084p3-835 | Fat | ESPE2015

How Early are Vascular Changes in Obese Children Among North Indian Population?

Umapathi Krishna Kishore , Yadav Sangeeta , Tyagi Sanjay , Mishra T K

Background: Obese children are known to be at high risk for vascular complications and there is paucity in Indian literature regarding the onset and magnitude of vascular complications. Carotid intima media thickness (cIMT) and Brachial artery distensibility are known to predict future atherogenesis.Objective and hypotheses: To compare vascular parameters of obese children aged 5–18 years with age and sex matched controls and its relationship with p...

hrp0084p3-836 | Fat | ESPE2015

Prader-Willi Syndrome – A General Picture of 51 Cases

Ito Simone , dos Santos Tiago Jeronimo , Passone Caroline , Franco Ruth , Damiani Durval

Objective and hypotheses: To describe the morphological characteristics of patients with Prader-Willi Syndrome (SPW) who have been followed in a Pediatric Endocrinology Outpatient Clinic.Method: We performed a retrospective study on 51 patients evaluating the age of diagnosis, genetic mutation, use of GH (rhGH), age of beginning of follow-up, and z-score of weight, height and BMI. Data on their first and latest visit to our clinic were compared....

hrp0084p3-837 | Fat | ESPE2015

Comparison of Two Family-Intervention (Parents Only vs Parent and Child) in the Treatment of Childhood Obesity

Meyerovitch Joseph , Yackobovitch-Gavan Michal , Wolf Dafna , Phillip Moshe , Shalitin Shlomit

Background: Obesity in adolescence is associated with a 70% likelihood of obesity or overweight in adulthood. Hence, effective intervention programs for childhood obesity in high-risk populations are needed.Objectives: i) To compare the efficacy of two intervention strategies, involving parents only vs parent and child, to a control group, in the treatment of childhood obesity. ii) To identify clinical demographical and biochemical predictors for decreas...

hrp0084p3-838 | Fat | ESPE2015

Bioavailable Vitamin D in Obese Children: The Role of Insulin Resistance

Grandone Anna , Del Giudice Emanuele Miraglia , Cirillo Grazia , Di Sessa Anna , Umano Giuseppina , Marzuillo Pierluigi , Capristo Carlo , Perrone Laura

Background: Studies examining vitamin D levels in association with childhood obesity usually do not concurrently measure levels of vitamin D-binding protein and do not calculate the unbound, bioavailable vitamin D, that is considered the fraction of 25-hydroxyvitamin D able to exert biological activity.Objective and hypotheses: To evaluate in a group of children for the most part obese i) the concentrations of both total 25-hydroxyvitamin D and of the bi...

hrp0084p3-839 | Fat | ESPE2015

Age at Menarche in Relation to BMI. Data from the Hellenic Action Plan for the Assessment, Prevention and Treatment for Childhood Obesity

Vlachopapadopoulou Elpis , Karachaliou Fotini-Eleni , Psaltopoulou Theodora , Koutsouki Dimitra , Manios Yannis , Bogdanis Grigoris , Karagianni Vileelmini , Michalacos Stefanos

Background: A secular trend towards earlier menarche has been observed.Objective and hypotheses: The correlation of age at menarche with the BMI as well as the maternal age at menarche and their BMI.Method: This is a cross-sectional study conducted from October 2012–December 2013. A pre-selected, representative elementary and high school cohort was derived, using stratification and PPS methodology. Parents responded to questio...

hrp0084p3-840 | Fat | ESPE2015

Are Age and Initial BMI-SDS in Obese Children and Adolescents Associated with the BMI-SDS Courses During and after the Attendance of an Inpatient Weight-Loss Program (LOGIC-Trial)?

Brandt Stephanie , Wabitsch Martin , Heitkamp Melanie , Geilhof Barbara , Langhof Helmut , Halle Martin , Siegrist Monika

Background: It has been discussed in literature, that being severely obese and adolescent are predictive for failure in a behavior based weight-loss program.Objective: To investigate the association between age and initial BMI-SDS with BMI-SDS courses during and after the attendance of an inpatient weight-loss program.Design: The LOGIC-trial involves overweight and obese children and adolescents (6–19 years), who participate i...

hrp0084p3-841 | Fat | ESPE2015

Turn off and Turn in: The Influence of Television Viewing and Sleep on Lipid Profiles in Children

Manousaki Despoina , Radji Sanyath , Barnett Tracie , Mathieu Marie-Eve , Gray-Donald Katherine , Henderson Melanie

Background: Physical activity is beneficial to lipid profiles, however the association between sedentary behaviours and paediatric dyslipidaemia remains controversial. Understanding these associations is critical given that youth are increasingly engaging in sedentary pursuits, and are sleeping, on average, 1 h less than children were 20 years ago.Objective and hypotheses: To investigate whether various forms of sedentary behavior/sleep predict lipid pro...

hrp0084p3-842 | Fat | ESPE2015

Hepatic Steatosis Influences Significantly the Cardiovascular Risk in Children with Metabolic Syndrome

Rutigliano Irene , De Filippo Gianpaolo , Vinci Roberta , Kyheng Christele , Petraccaro Agostino , Conoscitore Michele , Pettoello-Mantovani Massimo , Campanozzi Angelo

Background: Despite the metabolic syndrome in pediatrics is a well recognized entity, there is no unanimous consensus on exact value of MS to predict long-term cardiovascular risk. Hepatic Steatosis (HS) is another emerging condition associated to pediatric obesity.Objective and hypotheses: To evaluate the prevalence of MS in a large pediatric obese population, assess the relationship between MS and HS, and evaluating the possible role of HS in defining ...

hrp0084p3-843 | Fat | ESPE2015

Increased Glucagon-Like Peptide-1 Response to Oral Glucose in Prepubertal Obese Children

Marcovecchio M Loredana , Polidori Nella , Giannini Cosimo , De Giorgis Tommaso , Chiarelli Francesco , Mohn Angelika

Background: Over the last years a role for gastrointestinal hormones, such as glucagon-like peptide (GLP-1), in the pathogenesis of obesity and its complications, has been hypothesized. However, there are few data for the paediatric population.Objective and hypotheses: To assess whether there is a difference in post-load GLP-1 response in obese children compared to normal-weight peers and to assess the relationship with insulin responses.<p class="ab...

hrp0084p3-844 | Fat | ESPE2015

The Risk of Metabolic Syndrome among Dyslipidemic Children and Adolescents

Predieri Barbara , Colombini Giulia , Mazzoni Silvia , Bruzzi Patrizia , Lucaccioni Laura , Iughetti Lorenzo

Background: Lipid assessment is emerging as a useful and easy detectable tool to define the overall cardiovascular risk in children and adolescents. Nevertheless, no all dyslipidemic patients suffer the same cardiometabolic consequences.Objective and hypotheses: To compare anthropometric, biochemical and blood pressure variables among dyslipidemic children and adolescents according to the presence of metabolic syndrome (MetS).Metho...

hrp0084p3-845 | Fat | ESPE2015

RNAi as Tool to Study Molecular Mechanisms of Metabolic Adverse Reactions in Caenorhabditis Elegans

Hornle Manuela , Hellwig Isabelle , Hodgkinson Steve , Kaschka Wolfgang

Background: The introduction of second generation antipsychotic (SGA) drugs for the treatment of bipolar disorders has been associated with metabolic adverse reactions. Many studies cite significant weight gain as a common side effect, which is often attributed to dysfunction of glucose homeostasis and the development of dyslipidaemia. This in turn may trigger the early pathogenesis observed for example in type-2-diabetes. Factors controlling energy metabolism are largely cons...

hrp0084p3-846 | Fat | ESPE2015

Hypertriglicerydaemia in a Boy with Bardet-Biedl Syndrome – Case Report

Wojcik Malgorzata , Rogulska Katarzyna , Piotrowski Dawid , Zygmunt-Gorska Agata , Janus Dominika , Starzyk Jerzy B

Background: Bardet-Biedl syndrome (BBS) is a rare autosomal ciliopathy characterised by retinal dystrophy, obesity, post-axial polydactyly, renal anomalies, mental retardation and hypogonadism as well as minor features, which include diabetes mellitus, cardiac dysfunction and behavioural abnormalities. Hypertriglyceridaemia in BBS patients has not been reported to date.Objective and hypotheses: Presentation of the diagnosis and treatment of hypertriglice...

hrp0084p3-847 | Fat | ESPE2015

Uric Acid and Triglycerides/HDL Ratio as a Predisposing Factor for Metabolic Syndrome in Children

Katsa Maria Efthymia , Ioannidis Anastasios , Zyga Sofia , Tsironi Maria , Koutsovitis Paraskevas , Sachlas Athanasios , Kolovos Petros , Magana Maria , Daratsianou Maria , Paola Andrea , Gil Rojas

Background: Uric acid and Triglycerides/HDL ratio are an important risk factor for cardiovascular diseases.Aim: To investigate how Triglycerides/HDL ratio and uric acid are correlated with children’s biochemical and anthropometric characteristics, depending on the predisposition for metabolic syndrome (MetSyn).Methods: 110 students, 6–12 years old, living in Sparta-Greece, participated in our research. Anthropometric and ...

hrp0084p3-848 | Fat | ESPE2015

Increased Prevalence of 25-Hydroxyvitamin D Insufficiency and Deficiency among Overweight and Obese Children and Adolescents in Greece

Giannios Christos , Farakla Ioanna , Papadopoulos Georgios , Koniari Eleni , Papathanasiou Chrysanthi , Kassari Penio , Charmandari Evangelia

Background: The prevalence of childhood obesity has increased dramatically in the last decades and accounts for a significant increase in morbidity and mortality in adulthood.Objective and hypotheses: To determine the prevalence of 25-hydroxyvitamin D insufficiency and deficiency in overweight and obese children and adolescents.Method: 350 (n=350) children and adolescents (153 males (M), 197 females (F)) were recruited to ...

hrp0084p3-849 | Fat | ESPE2015

The Triglyceride-to-High Density Lipoprotein Cholesterol Ratio in Overweight Korean Children

Kang Yu Sun , Yoo Eun-Gyong

Background: Dyslipidaemia is related with the initiation and progression of atherosclerosis in children, and the total cholesterol (TC) and non-high density lipoprotein cholesterol (non-HDL-C) are commonly used screening tools for identifying children with dyslipidaemia. The triglyceride-to-high density lipoprotein cholesterol (TG/HDL-C) ratio has recently been reported as a marker of insulin resistance in obese children and adolescents.Objective and hyp...

hrp0084p3-850 | Fat | ESPE2015

Waist Height Ratio as a Marker of Obesity and Insulin Resistance in Adolescents

Nagesh V Sri , Sahay Rakesh Kumar , Kudugunti Neelaveni , Rao Vishnuvardhan , Hashmi Syed Mustafa , Vikram Aditya , Jiwani Sania , Hyder Sana

Background: Recent studies have shown a rising trend in pediatric obesity. However, studies dealing with the ultimate metabolic consequences of pediatric obesity and the means of accurately predicting these consequences are limited.Objective and hypotheses: To study the utility of WHtR as a marker of insulin resistance. To validate the presently used cutoffs (≧0.5) and validate its utility in populations studies.Method: 96 c...

hrp0084p3-851 | Fat | ESPE2015

Genotype and Clinical Characteristics in Korean Patients with Prader-Willi Syndrome: A Single Centre Study

Kim Yoo-Mi , Cheon Chong Kun , Kim Su Young

Background: Prader–Willi syndrome (PWS) is characterised by neonatal hypotonia, hypogonadism, progressive obesity, short stature, and mental retardation. This syndrome arises from a loss of expression of paternally derived genes on chromosome 15q11–13 region.Objective and hypotheses: The aim of this study was to investigate clinical characteristics and their genotypes in Korean patients with PWS.Method: The study included...

hrp0084p3-852 | Fat | ESPE2015

Comparison of the Insulin Resistance Index HOMA-IR between Obese and Normal Children

Rocheleau Ghislain , Dewitte Aude , Bonnefond Amelie , Weill Jacques

Background: Adult obese subjects are susceptible to an excess of cardiovascular events due to insulin resistance through the metabolic syndrome or hyperinsulinism itself. These deleterious factors go on and amplify from childhood into adulthood. To the best of our knowledge no comparison of insulin resistance indices has been performed between obese and normal children.Objectives: The main objective of this study is to compare the insulin sensitivity ind...

hrp0084p3-853 | Fat | ESPE2015

Nonalcoholic Steatohepatitis Leading to Cirrhosis of the Liver as a Complication of Hypothalamic Disorders in a Course of Craniopharyngioma – Case Report

Watrobinska Urszula , Bendysz-Golatowska Anna , Moszczynska Elzbieta , Szalecki Mieczyslaw

Background: Craniopharyngioma is low – grade malignant tumour with high survival rate. Its incidence is 0.5–2.0 cases per million persons per year. 30–50% of all cases occur in the childhood. The tumour location leads to numerous complications like deficits of pituitary function, impairment of vision, neuropsychological deficits and obesity. Excess body fat is observed in 40–50% of craniopharyngioma patients.Case presentation: We pres...

hrp0084p3-854 | Fat | ESPE2015

Association of Sleep Habits and Risk Factors for Metabolic Disorders in Children

Magana Maria , Zyga Sofia , Ioannidis Anastasios , Sachlas Athanasios , Katsa Maria Efthymia , Pistikou Anna Maria , Dimoliani Dafni Eleni Kougioumtzi , Daratsianou Maria , Kolovos Petros , Gil Andrea Paola Rojas

Background: Sleep is a complex and essential biological process that is required on a daily basis for all humans, playing a vital role in the maintenance of the homeostasis in short and long term.Aims and objectives: To investigate the role of sleep hours in correlation with risk factors for metabolic disorders in a children population.Methods: The program was implemented in 949 children (5–12 years old) living in Sparta-Greec...

hrp0084p3-855 | Fat | ESPE2015

Plasminogen Activator Inhibitor-1 as a Marker of Insulin Resistance in Obese Adolescents

Engiz Ozlem , Alioglu Bulent , Bagrul Denizhan , Karakaya Jale , Dallar Yildiz Bilge

Background: Obesity is considered to be a chronic inflammatory state in which the dysfunction of adipose tissue plays a central role. Adipose tissue is known to express and secrete a variety of products known as ‘adipokines’ including leptin, adiponectin, resistin, and visfatin, as well as cytokines and chemokines such as tumor necrosis factor-α (TNF-α), interleukin-6, and monocyte chemoattractant protein-1.Objective and hypotheses: T...

hrp0084p3-856 | Fat | ESPE2015

Relationship between Visceral Obesity and Plasma Fibrinogen in Obese Children

Hafez Mona , Masry Sahar El , Musa Noha , Fathy Marwa , Hassan Mona , Hassan Nayera , Tareef Mahmoud , Husseiny Mohamed El

Background: The prevalence of obesity in children and adolescents has increased significantly worldwide with an alarming rise of its co-morbidities. The excess of visceral adipose tissue is associated with hypertension, prothrombotic and pro-inflammatory states leading to cardiovascular diseases.Aim of the study: To find possible associations between visceral obesity and plasma fibrinogen, as one of the cardiovascular risk factors, in obese children....

hrp0084p3-857 | Fat | ESPE2015

Influence of GNRH Analogue on BMI in Girls with Precocious Puberty

Moayeri Heshmat

Background: Treatment with the gonadotropin – releasing hormone (GnRH) agonist is the treatment of choice for central precocious puberty (CPP).Objective and hypotheses: Concept have been expressed that GNRH treatment may be associated with increased BMI and it is controversial in some studies.Method: We studied the height, weight, and BMI of 52 girls that the majority of them had CPP. All patients were treated with GNRH analog...

hrp0084p3-858 | Fat | ESPE2015

Prevalence of Asthma Symptoms and Association with Obesity, Sedentary Lifestyle and Sociodemographic Factors: Data from the Hellenic National Plan for the Assessment, Prevention and Treatment of Childhood Obesity

Karachaliou Feneli , Vlachopapadopoulou Elpis , Psaltopoulou Theodora , Koutsouki Dimitra , Manios Ioannis , Bogdanis Grigoris , Sergentanis Theodoros , Panagiotopoulos Ioannis , Papadopoulou Anastasia , Chatzakis Agelos , Michalakos Stefanos

Background: The parallel increase in prevalence of asthma and obesity in childhood has led to an increasing body of evidence about a possible link between the two conditions.Objective and hypotheses: To assess the prevalence of asthma symptoms in a representative sample of Greek schoolchildren and to evaluate its association with overweight/obesity as well as other socioeconomic, demographic and lifestyle factors.Method: This is a ...

hrp0084p3-859 | Fat | ESPE2015

Long-Term Effects of Neonatal Over-Nutrition on Metabolic Equilibrium are Age and Sex Dependant

Argente-Arizon Pilar , Ros Purificacion , Diaz Francisca , Fuente-Martin Esther , Barrios Vicente , Chowen Julie A , Argente Jesus

Background: Neonatal over-nutrition (NON) can have a long-term effects on energy homeostasis and some of these effects may be sexually dimorphic.Objective and hypotheses: We aimed to determine how NON affects body weight (BW), body composition and cytokine levels throughout development and if these changes are sexually dimorphic. We hypothesised that the effects would be both age and sex dependant.Methods: At birth, Wistar rats wer...

hrp0084p3-860 | Fat | ESPE2015

Metabolic Syndrome in Greek Adolescents and the Effect of 6-Month Educational/Behavioural School Interventions

Bacopoulou Flora , Efthymiou Vassiliki , Papaefthymiou Maria , Landis Georgios , Palaiologos George , Kaklea Maria , Papassotiriou Ioannis , Chrousos George

Background: Data regarding the prevalence of metabolic syndrome (MS) in Greek adolescents and the effect of school interventions are scarce.Objective and hypotheses: To study the prevalence of MS in a representative sample of Greek adolescents and evaluate the impact of a 6-month educational-behavioral intervention.Method: Cross-sectional anthropometric data ((height, weight, waist circumference (WC)), blood pressure (BP), fasting ...

hrp0084p3-861 | Fat | ESPE2015

Decreased Insulin Sensitivity and Secretion in Obese Youth with High OGTT Derived 1 h Blood Glucose

Loredana M Loredana M , Marisi Elsa , Di Giovanni Ilaria , De Leonibus Chiara , Chiarelli Francesco , Mohn Angelika

Background: Obese adults with normal glucose tolerance (NGT) but 1-h post load glucose (1 hPG)≧155 mg/dl have an increased cardiometabolic risk. In children, preliminary data suggest that 1hPG≧132.5 mg/dl might identify those at higher risk of type 2 diabetes.Objective and hypotheses: To assess whether NGT obese youth with 1hPG ≧132.5 mg/dl (High-NGT) have worse insulin sensitivity and secretion compared to obese youth with 1hPG &#60...

hrp0084p3-862 | Fat | ESPE2015

Diagnosis and Treatment of Familial Hypercholesterolemia in Children – A Preliminary Report

Brandt Agnieszka , Bautembach-Minkowska Joanna , Hennig Matylda , Waseg Bartosz , Limon Janusz , Mysliwiec Malgorzata

Background: Heterozygous familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder occuring in 1:500 people. Patients with FH have a high risk of premature cardiovascular diseases. Today effective lipid-lowering therapies are available and it is a chance to extend the life of patients.Aims and objectives: The aim was to analyse the clinical data of children with FH from the Clinic of Pediatrics, Diabetology and Endocrinology and prelim...

hrp0084p3-863 | Fat | ESPE2015

Metabolic Syndrome Risk Factors in Obese Children and Adolescents

Azimova Shahnoza , Rakhimova Gulnora

Objective and hypotheses: The work was initiated to perform integral assessment of metabolic syndrome (MS) risk factors in obese children and adolescents.Method: We examined Uzbek 100 children and adolescents with exogenous-constitutional obesity (ECO) aged from 6 to 16 years (mean age 11.7±0.25); 54 (54.0%) boys and 46 (46.0%) girls among them. To develop prediction scale we used a modification of Bayesian probability, method for standardization of...

hrp0084p3-864 | Fat | ESPE2015

A Systemic Approach for the Management of the Program Entitled ‘Development of a National System for the Prevention and Management of Overweight and Obesity in Childhood and Adolescence in Greece’

Kassari Penio , Papaioannou Panagiotis , Charmandari Evangelia

Background: The prevalence of obesity has increased dramatically in Greece in the last two decades, and more than 35% of children and adolescents are currently overweight or obese. Prevention could be the key strategy for controlling the current epidemic of obesity.Objective and hypotheses: Prevention is the main scope of the Program entitled ‘Development of a National System for the Prevention and Management of Overweight and Obesity in Childhood a...

hrp0084p3-865 | Fat | ESPE2015

Waist Circumference to Body Height is a Suitable Measure of Cardiovascular Risk in Overweight and Obese Children

Yakovenko Vira , Teufel Ulrike , Henn Laura , Bettendorf Markus , Hoffmann Georg F , Grulich-Henn Juergen

Background: Several methods have been used to evaluate the risk of cardiovascular diseases in obese children. Both BMI and waist-to-hip ratio were suggested as risk factors. However, they did not prove to estimate the risk for cardiovascular events in adulthood. Recent studies suggest that the ratio of waist circumference to body height (WHtR) is a more reliable predictor for cardiovascular risk in 6-10-year old children (Kuba et al. 2013).Objec...

hrp0084p3-866 | Fat | ESPE2015

The Effectiveness of a Comprehensive and Personalized Plan of Action in the Prevention and Management of Overweight and Obesity in Childhood and Adolescence

Papadopoulos George , Farakla Ioanna , Bakopoulou Sophia , Giannios Christos , Koui Eleni , Georgiou Alexandra , Romas Stamatis , Terzioglou Eleni , Koniari Eleni , Papathanasiou Chryssanthi , Kassari Penio , Nicolaides Nicolas , Critselis Elena , Manios Yannis , Charmandari Evangelia

Background: Obesity in childhood and adolescence represents a major health problem of our century, and accounts for a significant increase in morbidity and mortality in adulthood.Objective and hypotheses: To investigate the effectiveness of a comprehensive and personalized plan of action in the prevention and management of overweight and obesity in childhood and adolescence.Method: 470 children and adolescents (mean age±SEM: 9...

hrp0084p3-867 | Fat | ESPE2015

Insulin Resistance in Adolescents with Screen Addiction and Attention-Deficit/Hyperactivity Disorder

Koprulu Ozge , Darcan Sukran , Ozbaran Burcu , Ata Emsal , Altinok Yasemin , Ozen Samim , Goksen Damla

Background: Screen (TV, tablet, smartphones, internet, video games, PC etc.) addiction is a growing problem in child health. The effect on insulin-glucose metabolism is not well known yet.Objective and hypotheses: To investigate the insulin resistance in screen addicted children.Method: We studied 108 children and adolescents aged 13.72±1.95 years (range 11–17 years). Participants were divided into three groups according ...

hrp0084p3-868 | Fat | ESPE2015

Ketogenic Diet in Paediatrics: Work in Progress

Miglioranzi Paola

Background: The effects of carbohydrate-restricted (ketogenic) diets on metabolic parameters in children have been incompletely assessed.Objective and hypotheses: Effective treatment options for childhood obesity are limited and the risk of significant co-morbidities increase sharply with age, especially in paediatric population where growth is normally still occurring. The purpose of this study was to evaluate the feasibility, the efficacy and the safet...

hrp0084p3-869 | Fat | ESPE2015

Severe Hypothalamic Obesity in a Girl with Craniopharyngioma – Case Report

Obara-Moszynska Monika , Harat Marek , Niedziela Marek

Background: Hypothalamic obesity is a form of obesity syndrome associated with a variety of hypothalamic disorders including intracranial tumors, infections, trauma, vascular problems and hydrocephalus and acquired or congenital functional defects in central energy homeostasis. The pathogenetic mechanisms underlying hypothalamic obesity are multifactorial. Weight gain results from the hypothalamus damage, which leads to excessive apetite and low metabolic rate, multiple pituit...

hrp0084p3-870 | Fat | ESPE2015

The Changes of Neuroendocrine Status in Children with Different Forms of Obesity

Zagrebaeva Olga , Solntsava Anzhalika , Mikhno Hanna , Dashkevich Helena

Background: Obesity is accompanied with the development of serious complications, including behavioural disorders. Obesity with impaired neuroendocrine status confirmed, but papers describing these interactions are a bit.Objective and hypotheses: To compare the state of neuroendocrine status in children with various forms of obesity and normal weight control to the evaluation of central hormonal regulators of energy balance.Method:...

hrp0084p3-871 | Fat | ESPE2015

Body Composition and Metabolic Risk Factors in Preschool Children

Lateva Mina , Popova Ralitsa , Galcheva Sonya , Georgieva Miglena , Iotova Violeta

Background: Recently childhood obesity shows trends of lowering age at start. Preschool children are still very physically active. A possible association between total and abdominal obesity and metabolic risk at preschool age could be of value for preventive measures.Objective and hypotheses: To investigate the relationship between body composition and some metabolic risk factors at preschool age.Method: A total of 40 (50% boys) he...

hrp0084p3-872 | Fat | ESPE2015

Evaluation of Alternatives to OGTT to Assess Glucose Intolerance and Diabetes in an Obese Paediatric Population

Elowe-Gruau Eglantine , Bouthors Therese , Vadnai Gael , Buzduga Mihaela , Laufer Daniel , Decarli Manuela , Borloz Sylvie , Stoppa-Vaucher Sophie , Phan-Hug Franziska , Hauschild Michael , Pitteloud Nelly

Background: Screening for glucose intolerance (GI) or type 2 diabetes (T2D) is recommended for obese children over 10 years of age (or onset of puberty) in the presence of ≧2 of the following risk factors: family history of T2D in a first- or second-degree relative, high risk ethnicity, signs of insulin resistance (IR) or associated conditions, or maternal gestational diabetes. The diagnostic importance of HbA1C levels is still controversial in children and adolescents....

hrp0084p3-873 | Fat | ESPE2015

Sex Differences in the Pubertal Response to High-Fat Diet

Freire-Regatillo Alejandra , Argente-ARizon Pilar , Diaz Francisca , Barrios Vicente , Arevalo Angeles , Argente Jesus , Garcia-Segura Luis Miguel , Azcoitia Inigo , Chowen Julie A

Background: It is well known that ingestion of a high fat diet (HFD) can induce rapid weight gain and metabolic imbalances. However, males and females are not equally susceptible to these effects. Furthermore, an individual may be more prone to gain weight during specific developmental periods.Aims and objectives: We aimed to analyse the response to the acute exposure to a HFD during pubertal/adolescent period and to determine whether males and females r...

hrp0084p3-874 | Fat | ESPE2015

Relation between Thyroid Function Tests and Cardiometabolic Risk Factors in Childhood Obesity

Vuralli Dogus , Tapci Esra , Dallar Yildiz Bilge

Background: It is known that obese children are at higher risk in terms of cardiovascular diseases when compared with normal weight children. Recent studies emphasizes on the fact that there is a relation between TSH and several cardiovascular risk factors in obese children.Objective and hypotheses: The aim of the study is to investigate the relation between cardiometabolic risk factors and thyroid function tests in obese children....

hrp0084p3-875 | Fat | ESPE2015

İnsulin Infusion Treatment Option in Severe Hypertriglyceridaemia Induced Pancreatitis

Ustyol Ala , Atabek Mehmet Emre , Yuksekkaya Hasan Ali , Dorum Meltem

Background: The risk of pancreatitis increases when triglyceride levels rise above 1 000 mg/dl. This requires particular attention in subjects with type 2 diabetes, which is accompanied by elevated triglyceride levels in one in every two patients. Apheresis, a treatment option in pancreatitis developing secondary to hypertriglyceridemia, is expensive and not available in every centre. Another option, heparin administration, may result in rebound hypertriglyceridaemia. Thirdly,...

hrp0084p3-876 | Fat | ESPE2015

Obesity has a Significant Impact on Hyperandrogenemia Only after Puberty in Korean Girls

Kang Min Jae , Shim Young Suk , Oh Yeon Joung , Hwang Il Tae , Yang Seung

Background: As metabolic complication and polycystic ovarian syndrome due to childhood obesity is rising, the role of hyperandrogenemia (HA) and hyperinsulinism is receiving attention.Objective and hypotheses: The aim of this study was to investigate the presence or absence of obvious HA according to pubertal status and to find potential etiologic determinants of HA in Korean obese girls.Method: We analysed 91 subjects aged 6–...

hrp0084p3-877 | Fat | ESPE2015

Higher Hb1Ac in Obese Prader-Willi Syndrome Patients vs Obese Controls

Passone Caroline , dos Santos Tiago Jeronimo , Ito Simone Sakura , Ybarra Marina , Cominato Louise , Franco Ruth , Damiani Durval

Background: Obesity in Prader-Willi Syndrome has peculiar features associated to reduced lean body mass which could confer different metabolic characteristics.Objective and hypotheses: The aim of this study is to describe and to compare the metabolic profile in obese patients and obese Prader-Willi syndrome patients (OPWS) followed in a Pediatric Endocrinology outpatient clinic.Method: 45 obese and 22 OPWS patients between 8 and 20...

hrp0084p3-878 | Fat | ESPE2015

Obese Children and Adolescents: Reasons for Non-compliance with Follow-up Scheduling

Drosatou Chrysoula , Vlachopapadopoulou Elpis-Athina , Karachaliou Feneli , Dikaiakou Eirini , Anagnostou Elli , Patinioti Ioanna , Petrou Vassilios , Michalakos Stefanos

Background: Non-compliance is a major issue for treatment failure in childhood obesity.Objective and hypotheses: To identify the barriers of adherence to weight management programs, of obese children and adolescents.Method: A descriptive, ongoing study based on phone recorded questionnaires with the use of information from the medical records. The study group consisted of 85 overweight and obese children and adolescents (M/F=46/39)...

hrp0084p3-879 | Fat | ESPE2015

Cardiometabolic Risk Factors in Overweight/Obese Children and Adolescents and Family History of Cardiovascular Disease

Karabouta Zacharoula , Papandreou Dimitrios , Makedou Areti , Rousso Israel , Athanassiadou-Piperopoulou Fani

Background: Global prevalence of childhood obesity has increased from 4.2 to 6.7% in recent decades. Dyslipidaemia predisposes to cardiovascular disease (CVD) in adults. Family history (FH) of CVD is used as a screening tool for dyslipidaemia in children/ adolescents, however with controversial sensitivity.Objective and hypotheses: Purpose of the study was to identify and examine the effects of possible cardiovascular (CV) risk factors in overweight/obes...

hrp0084p3-880 | Fat | ESPE2015

Healthcare Professionals’ Perception of Overweight in Preschool-aged Children

Bocca Gianni , Corpeleijn Eva , Broens Jasper , Stolk Ronald , Sauer Pieter

Background: Childhood obesity is still increasing worldwide. Early recognition of overweight or obesity in children by healthcare professionals is of utmost importance, allowing interventions to start at a young age.Objective and hypotheses: We studied whether healthcare professionals adequately perceive preschool children’s overweight and whether this is influenced by their own BMI.Method: Healthcare professionals received a ...

hrp0084p3-881 | Fat | ESPE2015

Evaluatıon of the Relationship between Serum Adropın Levels and Blood Pressure in Obese Children

Altincik Ayca , Sayin Oya

Background: The prevalence of obesity and related cardiovascular comorbodities are increasing rapidly. Adipokines play the major role on the pathogenesis of obesity related inflammation and hypertension.Objective and hypotheses: The aim of the study was to evaulate the serum adropin levels in obese children and to determine the relationship between adropin levels and blood pressure in pediatric age group.Method: 40 obese children (...

hrp0084p3-882 | Fat | ESPE2015

Adipocyte Fatty Acid Binding Protein is Related to Weight Status and Metabolic Risk Markers in Childhood Obesity

Kaepplinger Jakob , Petroff David , Herget Sabine , Reichardt Sandra , Grimm Andrea , Kratzsch Jurgen , Bluher Susann

Background: Adipocyte fatty acid binding protein (aFABP) regulates intracellular transport of fatty acids and seems to be involved in the pathogenesis of the Metabolic Syndrome. aFABP overproduction leads to increased cholesterol and triglyceride accumulation and to higher expression of pro-inflammatory genes. In adults aFABP seems to promote insulin resistance and atherosclerosis, and aFABP levels are significantly higher in obese compared to lean subjects. Fat mass, lipid ma...

hrp0084p3-883 | Fat | ESPE2015

Investigating Predisposing Factors for Childhood Obesity

Magana Maria , Routsi Kleopatra , Zyga Sofia , Panoutsopoulos George , Ioannidis Anastasios , Tsironi Maria , Pistikou Anna-Maria , Kougioumtzi-Dimoliani Dafni-Eleni , Kolovos Petros , Gil Andrea Paola Rojas

Background: Childhood obesity is considered to be an epidemic in developed countries that can negatively affect children’s health and psychology.Aims and objectives: To investigate the nutritional and environmental factors that lead to the presence of childhood obesity and its complications.Methods: A total of 949 students, 3–12 years old, living in Sparta–Greece, have participated in our research. Their lifestyle an...

hrp0084p3-884 | Fat | ESPE2015

Vitamin D Status in Iranian Obese and Non-obese Children

Sayarifard Fatemeh , Motlaghzadeh Yasaman , Sayarifard Azadeh , Allahverdi Bahar

Background: Vitamin D deficiency is now a critical issue due to its high prevalence and side effects.Objective and hypotheses:: We assessed the serum vitamin D status of obese and non-obese children and comparing their therapeutic response to identical oral vitamin D consumption in Iran.Method: This study was performed in children aged 2–14 years at Children Medical Center of Tehran in Iran. At first, the serum 25-hydroxy vita...

hrp0084p3-885 | Fat | ESPE2015

Is vitamin D Important Player in Hepatosteatosis in Childhood Obesity?

Ozsu Elif , Topcu Feyza Nur , Tepe Derya Acar

Background and aim: Childhood obesity is one of the most serious public health problem. Obesity-related complications such as hepatic steatosis or type 2 diabetes can now be monitored even during early childhood. The aim of the study was to examine the relationship between vitamin D levels and obesity with hepatosteatosis (HS) in children.Methods: A total of 128 children with obesity were included in this study. HS was diagnosed using ultrasonography. HS...

hrp0084p3-886 | Fat | ESPE2015

Obesity in School Children of Zahedan-Iran; Double Burden of Weight Disorders

Soheilipour Fahimeh , Pourzahabi Zeinab , Lotfi Maryam , Moradi-Lakeh Maziar , Jolfaie Atefeh Ghanbari

Background: Obesity has a permanent effect on children’s health and acts as a major risk factor for chronic diseases. Therefore considering the children’s BMI is a vital parameter at each visit. This study was performed to measure prevalence of obesity and its determinants in school children of Zahedan in Iran; Zahedan is the capital of Sistan-and-Balouchestan province which is known to have the highest prevalence of underweight in Iranian children.<p class="abst...

hrp0084p3-887 | Fat | ESPE2015

Sports Regulated and Lipid Profile in Children and Adolescents with Overweight

Trabazo Rosaura Leis , Cobela Rocio Vazquez , Garcia Concepcion Aguilera , Lozano Gloria Bueno , Meneses Josune Olza , Campos Mercedes Gil , Carpente Juan Jose Bedoya , Feijoo Lidia Castro , Aznar Luis Moreno , Hernandez Angel Gil

Introduction: Obesity is the most common nutritional disorder in the paediatric age. Decreased physical activity and increased inactivity are important factors that are involved in this pandemic. The highest prevalence of obesity in Europe is in the South.Objective: To study the relationship between the practice of a regulated sport and lipid profile in overweight children and adolescents.Material and methods: 318 overweight childr...

hrp0084p3-888 | Fat | ESPE2015

Weight and the Factors Influencing it in a Cohort of School Aged Children

Pop Raluca , Capraru Oana , Pascanu Ionela

Background: Weight disturbances in children are an important problem, both underweight and obesity having important health consequences. There is an ongoing debate about their cause, the risk factors involved and the need for public health policies focused on their prevention.Objective and hypotheses: The aim of this study was to estimate the prevalence of weight disturbances in a cohort of school-aged children and to analyse some factors considered to p...

hrp0084p3-889 | Fat | ESPE2015

Dietary Patterns in a Group of Obese Children

Pop Raluca , Pop Marian

Background: Obesity and overweight are important disturbances, considering their consequences, especially in children. Diet composition is an important factor involved in weight management.Objective and hypotheses: The aim of this study was to analyse the food pyramid and dietary patterns of obese children.Method: An observational study was conducted targeting obese children from Romania. The study included 63 children, age 3–...

hrp0084p3-890 | Fat | ESPE2015

Does Vitamin D Influence Energy Metabolism in Children and Adolescents?

Wedrychowicz Anna , Sztefko Krystyna , Starzyk Jerzy

Background: Recent years bring a lot of data of the important role of vitamin D in different physiological processes, including a prevention from pathological states.Objective and hypotheses: The aim of the study was to analyze associations between serum level of vitamin D and some markers of glucose and lipid metabolism but also as well bone-related molecules as adipokines and in children and adolescents.Method: 57 patients, 40 wi...

hrp0084p3-891 | Fat | ESPE2015

Bone Age Assessment and Glucose Metabolism in Overweight and Obese Children

Paul Corina , Mogoi Mirela , Velea Iulian

Background: Bone age (BA) tends to exceed chronological age (CA) in obese children. There are studies showing that insulin may directly influence skeletal growth. Objective: To determine whether there is an association between BA and glucose metabolism in a group of overweight and obese children.Methods: The study included 55 obese or overweight children, mean age: 11.56±3.07 years old. Anthropometric indexes (weight, height, BMI, waist circumferenc...

hrp0084p3-892 | Fat | ESPE2015

The Triglyceride-to-HDL Cholesterol Ratio is Associated with Insulin Resistance in Obese Boys But Not in Obese Girls

Massa Guy , Bervoets Liene , Massa Jonas , Zeevaert Renate

Background: Children and adolescents with obesity often have insulin resistance (IR) and are at increased risk to develop coronary heart disease (CHD) in adulthood. The triglyceride to HDL-cholesterol (TG/HDL-C) ratio reflects small, dense low-density lipoprotein (LDL), an atherogenic lipoprotein particle that strongly predicts CHD.Objective and hypotheses: To evaluate the TG/HDL-C ratio in obese children and adolescents and study the relationship with a...

hrp0084p3-893 | Fat | ESPE2015

Experience with Sleeve Gastrectomy in Adolescent Obese Subjects and in Prader-Willi Syndrome

Fintini Danilo , Bocchini Sarah , Caccamo Romina , Grugni Graziano , Cappa Marco , De Peppo Francesco , Crino Antonino

Background: Prader Willi syndrome (PWS) results from the loss of paternally imprinted genes on chromosome 15q11–15 and is characterized by neonatal hypotonia, short stature, hypogonadism, aggressive food-seeking behavior, hyperphagia, and obesity with difficult in losing weight only with nutritional approach.Objective and hypotheses: We report our experience on sleeve gastrectomy in PWS and obese subjects during 12 months of follow-...

hrp0084p3-894 | Fat | ESPE2015

Metabolic Syndrome and Inflammatory Markers in Obese Children at Chiang Mai University Hospital

Sontichai Watchareewan , Dejkhamron Prapai , Unachak Kevalee , Kongtaweelert Prachya

Background: Inflammatory markers in obesity with metabolic syndrome (MS) have been postulated to be associated with development of CVS diseases in adults.Objective: To study inflammatory marker levels in obese children.Method: A cross-sectional study of obese children was conducted. Children with history of endogenous obesity, chronic diseases, drug ingestion/any acute illnesses within two weeks prior to enrolment were excluded. Fa...

hrp0084p3-895 | Fat | ESPE2015

Evaluating Liver Enzymes and Cholesterol Levels in Newly Diagnosed Obese Children Attending the University of Port Harcourt Teaching Hospital

Yarhere Iroro , Jaja Tamunopriye

Background: Increasing obesity epidemic is not limited to the developed world, but is gradually gaining grounds in the developing countries. The attendant metabolic syndrome is one major complication but liver disease seems to be attaining significant proportion in adult and adolescent obese patients.Objective and hypotheses: To evaluate the extent of liver damage in obese children attending the Paediatric endocrinology clinic using liver enzyme levels.<...

hrp0084p3-896 | Fat | ESPE2015

Prevalence of Excess Weight in Adolescents at Primary Health Care Units in South Brazil

Vargas Deisi Maria , de Medeiros Ana Carolina Santin , Klieman Elis , Eberhardt Isabel , Piesanti Vera Janete , Pasa Simone , da Silva Claudia Regina Lima Duarte , Coutinho Luciane Azevedo , Simao Vilma Margarete

Background: In the past decades Brazil has experienced a nutritional transition process characterised by a significant reduction in malnutrition and progressive increase in overweight and obesity. Nutritional education and precocious interventions are useful strategies to combat excess weight in childhood and adolescence. According to the World Health Organization (WHO), there were more than 40 million children overweight in the world in 2011. In Brazil, the prevalence of exce...

hrp0084p3-897 | Fat | ESPE2015

Effect of Overweight and Obesity on Spinal Deformities for Children 5–7 Years

Aghaei Marzieh , Shapoori Javad

Background: Obesity is one of the factors of musculo-skeletal disorder by its weight stress. It can change body shape and axis of weight balance, especially in growth, which can affect skeletal curvature.Objective and hypotheses: The objective of this study was to determine the prevalence of spinal abnomalies in elementary school entry children and evaluate some cofactors related to obesity in child.Method: In a cross-sectional stu...

hrp0084p3-898 | Fat | ESPE2015

A Case of Rapid Onset Obesity, Hypoventilation, Hypothalamic Dysregulation and Neuroendocrine Tumours-ROHHADNET Syndrome

Atapattu Navoda , Dissanayaka Lalitha , Arulmoli S

Background: Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHADNET) is a rare disorder which presents in early childhood.Case presentation: Four years old girl was referred to endocrinology unit with a history of excessive weight gain. Parents noticed a rapid weight gain from 3 years of age with increase food seeking behaviour and daytime somnolence. Her weight was >95th centile and her height was o...

hrp0084p3-899 | Fat | ESPE2015

The Influence of Physical Activity and Physical Fitness in the Metabolic Profile and Microcirculation of Eutrophic, Overweight and Obese Children 5–12 Years of Age

da Penha Jociene Terra , Gazolla Fernanda Mussi , Carvalho Cecilia Noronha de Miranda , Madeira Isabel Rey , Rodrigues Jr Flavio , Machado Elisabeth de Amorim , Sicuro Fernando Lencastre , Farinatti Paulo de Tarso Veras , Collett-Solberg Paulo Ferrez

Background: Obesity is a worldwide epidemic affecting adults and children. Social changes throughout history have contributed to modifications in nutrition and physical activity levels. These changes in lifestyle affected health, increasing the number of metabolic and cardiovascular diseases. Obese children already have a low grade systemic inflammation as well as markers of increased cardiovascular risk. The endothelial function is an important and early marker of atheroscler...

hrp0084p3-900 | Fat | ESPE2015

Predicting Early Cardiovascular Risk in Obese Children Based on Anthropometry

Cipollone Claudia , Piccorossi Alessandra , Antenucci Annarita , Greco Carla , Lasorella Stefania , Farello Giovanni

Background: Early predictors of cardiovascular risk using anthropometric and laboratory variables available in the general practice in obese children are poorly identified.Objective and hypotheses: To identify best predictors of early cardiovascular risk in obese children between anthropometric and laboratory parameters.Method: Cardiovascular risk was determined by measuring intima-media thickness of the right common carotid artery...

hrp0084p3-901 | Fat | ESPE2015

Metabolic Syndrome Rates Among Adolescents of the Greek School Community

Kotanidou Eleni , Kleisarchaki Angeliki , Mouzaki Konstantina , Kokka Paraskevi , Kyrgios Ioannis , Tsara Iro , Efstratiou Efthimia , Haidich Anna-Bettina , Papageorgiou Vagia , Eboriadou-Petikopoulou Maria , Galli-Tsinopoulou Assimina

Background: Adolescent obesity constitutes a phenomenon with epidemic prevalence in a worldwide context. Increased rates of metabolic syndrome represent a consequence of this epidemic, leading to high risk for chronic diseases in adolescence. The study herein, presents the primary outcomes of a school-based intervention trial regarding the control of the metabolic syndrome among adolescents of Northern Greece.Aims and objectives: To investigate the preva...

hrp0084p3-902 | Fat | ESPE2015

Identification and Management of Obesity by General Paediatricians in the UK

Easwariah Madhu , Mann Jake , Goonetilleke Rajiv

Background: A third of children in the UK are obese or overweight. The majority are not in contact with medical services. Presentation to general paediatricians for unrelated condition may pose an opportunity to identify children with obesity. The UK obesity services for Children & Adolescents (OSCA) group have produced guidelines for management of obese children in secondary care.Objective and hypotheses: Determine the prevalence of obesity in gener...

hrp0084p3-903 | Fat | ESPE2015

Genotype and Phenotype Characterisation in Two Patients with MEHMO Syndrome

Stanik Juraj , Skopkova Martina , Stanikova Daniela , Ukropec Jozef , Danis Daniel , Kurdiova Timea , Ukropcova Barbara , Ticha Lubica , Klimes Iwar , Gasperikova Daniela

Background: MEHMO (microcephaly, epilepsy, hypogenitalism, mental retardation, obesity) is a rare disorder with X-linked inheritance. Only three families with this disorder were described previously, with the linkage to a region on X chromosome. No specific gene has been identified so far.Aims and objectives: The aim was to identify the genetic etiology in two unrelated Slovak male probands (4.5 and 1.5 years old respectively) with the clinical diagnosis...

hrp0084p3-904 | Fat | ESPE2015

Generalized Idiopathic Benign Acanthosis Nigricans in Childhood

Isguven Pinar , Ermis Bahri

Background: Acanthosis nigricans (AN) is a dermatosis characterised by velvety hyperpigmentation, skin thickening, and papillomatosis. AN is generally associated with endocrine disorders (diabetes mellitus, obesity, polycystic ovary syndrome), drugs, and malignancy. In rare cases, it can be unrelated to any systemic disease. Here, we report on a 5-year-old boy from Turkey with diffuse, progressive skin hyperpigmentation.Case report: He was born in a non-...

hrp0084p3-905 | Fat | ESPE2015

Potential Connection of Dyslipidaemia with BMI and Associated Disorders in Obese Children and Adolescents

Navasardyan Lusine , Markosyan Renata

Background: It is used to define body weight status in children and adolescents using age- and gender-corrected for BMI-SDS. Also excess body weight (EBW) is increasingly applicable to children and adolescents (BMI 99-th percentile). BMI seems to be informative for the severity of obesity, but not for relevant risks of dyslipidaemia.Objective and hypotheses: To reveal the potential connections between absolute levels of lipids and BMI, as well as several...

hrp0084p3-906 | Fat | ESPE2015

Deficiency of 25-(OH) D-Vitamin in Adolescents with Obesity

Matveeva Mariia , Samoylova Julia

Objective: To evaluate the level of 25 (OH) D – vitamin in obese adolescents living in the South of Russia.Materials and method: We examined 20 obese adolescents with varying degrees of severity, aged 15.5±0.3 years, ten girls and boys. The comparison group consisted of ten healthy adolescents matched for age and sex. Obesity was calculated by BMI. Level of 25-(OH) D – vitamin was studied in the laboratory by ELISA (nmol/l). Furthermore, t...

hrp0084p3-907 | Fat | ESPE2015

The Correlation Study on Childhood Obesity, Insulin Resistance and Androgens

Xiong Feng , Zhang Yu-Qing , Ding Xiao-Yan , Wang Dong-Gang , Zhu Min

Background: Adolescent hyperandrogenemia is prophase of polycystic ovary syndrome. Obesity is one important cause of hyperandrogenemia. Whether hyperandrogenemia has happened in obese children is need to explore.Aims and objectives: To investigate the levels of insulin and androgens in obese children, analysis the correlation between insulin resistance and androgens, and comparison on the differences of androgens levels between obese boys and girls, and ...

hrp0084p3-908 | Fat | ESPE2015

The Prevalence of Obesity in Children and Adolescents in the Udmurt Republic

Kovalenko Tatiana , Larionova Maria

Background: Obesity is an increasing problem among children and adolescents in recent decades however official statistics are contradictory.Objective and hypotheses: The purpose of this epidemiological study was to determine the prevalence of obesity in children and adolescents in the Udmurt Republic – the region in European part of the Russian Federation with a child population of 300 thousand people.Method: According to the ...

hrp0084p3-909 | Fat | ESPE2015

Survey Serum 25-Hydroxyvitamin D Concentration in Obese Children and Clinical Significance in Chinese Population

Yang Yu , Xu Lei

Background: Simple obese is a worldwide public health problem. Recent studies suggested a possible relationship between obese and vitamin D deficiency.Objective and hypotheses: To discuss the relationship between 25-Hdroxyvitamin D with glucose and lipid metabolism of simple obese in Chinese children.Method: 65 children with obeses (35 mild-to-moderate, 50 severe) and sixty-two children with normal weight were enrolled in this tria...

hrp0084p3-910 | Fat | ESPE2015

Clinico-Biochemical Correlation Among Children with Obesity and Metabolic Syndrome

Yadav Sangita , Umapathi Krishna Kishore , Mishra T K

Background: Childhood obesity associated with risk of developing metabolic syndrome (MetS) and paucity in Indian literature regarding correlation between clinical and biochemical parameters in obese and MetS.Objective and hypotheses: Comparing clinical and biochemical correlation of obese children, controls and MetS.Method: Eighty children (40 obese and 40 age and sex matched controls) 5–18 years recruited after approval by In...

hrp0084p3-911 | Fat | ESPE2015

Clinical and Phenotypic Patterns of Overweight and Obese School Children

Furdela Victoriya

Results of epidemiological studies of 540 9–17 years old school children in Ternopil city are presented in this article. The aim is to determine the incidence of overweight, obesity, metabolic syndrome and hypertension among Ternopil schoolchildren and to trace clinical and phenotypic features of these pathological conditions among them. The results showed that the incidence of overweight among schoolchildren is 11.1% and obesity is 4.8% (11.8% of girls and 14.8% of boys)...

hrp0084p3-912 | Fat | ESPE2015

In Different Method of the Evaluation of State of Feeling of Obese Children; Goodenough Harris ‘the Draw-a-person’ Test

Ergur Ayca Torel , Kirdag Gaye Asik , Ucar Seda

Objective: Psychosocial problems which the obesity caused is one of the most important reasons that impede success of treatment. Researches indicate that, majority of all obese children have depression. In this study, the effect of obesity on state feeling (cognitive functions and socioemotional adaptation) were investigated in a different special test. To this end obese and nonobese young patients were compared by a special test determines the ability of mind and con...

hrp0084p3-913 | Fat | ESPE2015

Phenotypic Study of Obesity in Children and Adolescents

Fedala Soumeya Nora , Haddam Ali El Mahdi , Ali Leyla Ahmed , Meskine Djamila , Chentli Farida

Background: Child Obesity is a major health problem. It is mainly due to a high diet and low physical activity. In some cases, they may be due to genetic causes. It must be detected and treated precociously due to an increased risk of early onset of diseases, including diabetes and heart disease.Objective and hypotheses: Search the frequency, clinical and etiological characteristics of obesity in children and adolescents.Method: Th...

hrp0084p3-914 | Fat | ESPE2015

Association of Serum Levels of 25(OH) Cholecalciferol and Childhood Obesity

Iezzi Maria Laura , Varriale Gaia , Megalooikonomou Anastasios , Di Loreto Simona , Zagaroli Luca , Torge Nunzia

Background: Vitamin D is now recognised as a prohormone, essential for the maintenance of mineral homeostasis, calcium metabolism and normal skeletal architecture. 30 ng/ml or greater can be considered sufficient serum levels. The prevalence of vitamin D deficiency among severely obese children is almost 49% caused by the fact that it is sequestered in the larger body pool of fat of such individuals, being vitamin D fat soluble. Vitamin D deficiency has been recently associate...

hrp0084p3-915 | Fat | ESPE2015

Comparison of Lipid Profile in Active and non Active Obese Children in Qom-Iran

Shapoori Javad , Aghaei Marzieh

Background: Obesity and nonactivity particularly in child hood can associated in cardiovascular disease in adult hood.Objective and hypotheses: Aim of this study was comparison of lipid profile in active and non active obese children.Method: The participants in this study who where obese children 8–10 years, according to cut off BMI>85% percentile, that selected by cluster sampling method. After obtaining consent.they comp...