ESPE Abstracts (2015) 84 P-1-140

Impaired Motor Function in Turner Syndrome: What is the Relationship to Performal Intelligence Scores?

Betül Taskina, Chris Verhaakb, Marlou Essinkc, Marlies Kempersd, Anja Vinckb, Ria Nijhuis-van der Sandene & Janiëlle van Alfen-van der Veldena

aDepartment of Pediatrics, Amalia Children’s Hospital, Radboudumc, Nijmegen, The Netherlands; bDepartment of Psychology, Amalia Children’s Hospital, Radboudumc, Nijmegen, The Netherlands; cdepartment of Physical Therapy, Amalia Children’s Hospital, Radboudumc, Nijmegen, The Netherlands; dDepartment of Genetics, Amalia Children’s Hospital, Radboudumc, Nijmegen, The Netherlands; eDepartment of Allied Health Sciences, IQ Health Care, Radboudumc, Nijmegen, The Netherlands

Background: Although motor performance is often impaired in patients with Turner syndrome, the exact prevalence of motor problems is unknown. Detailed studies on specific motor profiles are lacking and the exact relationship between performal IQ and motor function is unknown.

Aims and objectives: 1. To describe motor performance in our population of children and adolescents with Turner syndrome including the differentiation in specific motor skill domains. 2. To identify the relationship between motor performance and performal intelligence scores.

Methods: Participants were enrolled at the Radboudumc Turner Centre of Expertise, Nijmegen, the Netherlands. For the evaluation of motor performance, the Movement Assessment Battery for Children-2 (MABC-2) was used. The MABC-2 includes a total score and 3 domain scores on 1) Manual Dexterity, 2) Ball Skills and 3) Static and Dynamic Balance. The WPSSI-III (for children) and the WISC-III (for adolescents) was used to measure total IQ (tIQ), verbal IQ (vIQ) and performal IQ (pIQ).

Results: More than half (53.1%) of the 65 participants (age 11.8±4.3 SD years) scored below the 15th percentile for total motor performance. Patients showed slightly better results on Manual Dexterity compared with Balls Skills and Static and Dynamic balance (respectively 32.2% vs 57%% and 42.9% of the patients had a score below the 15th percentile; P<0.001). There was no significant correlation between motor performance and tIQ, vIQ or pIQ.

Conclusions: Remarkably impaired motor performance is present in more than half of the girls with Turner syndrome. Patients showed slightly better test results on Manual Dexterity and had more difficulties with time related tasks. We found no correlation between motor function tests and pIQ which confirms earlier studies of our group.

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