Background: The incidence of type 1 diabetes mellitus (T1DM) in children and adolescents has increased worldwide. However, the epidemiology of T1DM among Korean children has not been reported since 2001.
Objective and hypotheses: We therefore investigated the incidence of T1DM in Korean children and adolescents in 20122013 and compared it with data from 19952000.
Method: Data were obtained from the National Health Insurance Service (NHIS) registry, and age- and sex-specific incidence rates were calculated per 100 000 population.
Results: A total of 443 patients (204 boys and 239 girls, aged <15 years) with T1DM were registered in the NHIS in 20122013. The incidence rate per 100 000 population was 2.97 (95% confidence interval (CI) 2.703.26). We found incidence rates of 1.39 (95% CI: 1.071.77), 2.95 (95% CI: 2.473.49), and 4.25 (95% CI: 3.734.82) in children aged 04 years, 59, and 1014 years respectively. The T1DM incidence was 2.64 (95% CI: 2.293.33) in boys and 3.33 (95% CI: 2.923.77) in girls. A higher T1DM incidence was seen in 20122013 than 19952000 (incidence rate ratio 2.17, 95% CI: 1.932.43; P<0.001). The annual increase in T1DM incidence was 5.3% (95% CI: 4.56.1%) between 1995 and 2013.
Conclusion: We observed a significant increase in T1DM incidence in our study. This increase was higher in boys than girls and highest in youth aged 1014 years. Studies to evaluate the long-term epidemiological trend of T1DM incidence should be performed.
01 - 03 Oct 2015
European Society for Paediatric Endocrinology