ESPE Abstracts (2015) 84 P-3-723

The Investigation of Frequency of Diabetic Ketoacidosis in Children with New-onset Diabetes Mellitus Type 1

Goar Okminyana, Lubov Samsonovaa, Elena Kiselevaa, Oleg Latysheva, Evgenia Evsukovab, Irina Kolominab & Elvira Kasatkinaa


aRussian Medical Academy of Postgraduate Education Studies, Moscow, Russia; bTushino City Childrens Hospital, Moscow, Russia


Background and aims: The aim of this study was to investigate the frequency of diabetic ketoacidosis and diagnostic mistakes in onset diabetes mellitus type l in children and their relationship with age.

Materials and methods: In this study were included 269 patients (from 7 month to 17 years) in onset diabetes mellitus type l since 2010–2013. All patients were divided in to two groups. The first group consists of 92 patients (children were younger than 5 years) and the second group consists of 177 patients (children were more senior than 5 years).

Results: Diabetic ketoacidosis was revealed at 137 of 269 (50.9%) patients: 56 children younger 5 years and 81 more than 5 years. In the first group the frequency of diabetic ketoacidosis was 60.8% (56 from 92) and in the second group 45.7% (81 from 177, P=0.026). Among 269 patients with diabetes mellitus type l in 25 (9.3%) children was wrong diagnose. In the same time 24 (17.5%, P=0.05) from 137 children with diabetic ketoacidosis had wrong diagnoses. Wrong diagnoses among patients with diabetic ketoacidosis were: 56% – appendicitis, 20% – pneumonia or bronchial asthma, 20% – meningitis, 4% – pyelonephritis. In the first group the frequency of diagnostic mistakes was 25% (14 from 56), in the second group – 12.3% (ten from 81, P=0000).

Conclusion: The frequency of diabetic ketoacidosis in new-onset diabetes mellitus type l in children was high (50.95%). Diagnostic mistakes were more often among children with diabetic ketoacidosis. Diabetic ketoacidosis occurred more often in children under 5 years. Diagnostic mistakes also took place more often in children under 5 years.

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