Background and aims: The aim of this study was to investigate the frequency of diabetic ketoacidosis and diagnostic mistakes in onset diabetes mellitus type l in children and their relationship with age.
Materials and methods: In this study were included 269 patients (from 7 month to 17 years) in onset diabetes mellitus type l since 20102013. All patients were divided in to two groups. The first group consists of 92 patients (children were younger than 5 years) and the second group consists of 177 patients (children were more senior than 5 years).
Results: Diabetic ketoacidosis was revealed at 137 of 269 (50.9%) patients: 56 children younger 5 years and 81 more than 5 years. In the first group the frequency of diabetic ketoacidosis was 60.8% (56 from 92) and in the second group 45.7% (81 from 177, P=0.026). Among 269 patients with diabetes mellitus type l in 25 (9.3%) children was wrong diagnose. In the same time 24 (17.5%, P=0.05) from 137 children with diabetic ketoacidosis had wrong diagnoses. Wrong diagnoses among patients with diabetic ketoacidosis were: 56% appendicitis, 20% pneumonia or bronchial asthma, 20% meningitis, 4% pyelonephritis. In the first group the frequency of diagnostic mistakes was 25% (14 from 56), in the second group 12.3% (ten from 81, P=0000).
Conclusion: The frequency of diabetic ketoacidosis in new-onset diabetes mellitus type l in children was high (50.95%). Diagnostic mistakes were more often among children with diabetic ketoacidosis. Diabetic ketoacidosis occurred more often in children under 5 years. Diagnostic mistakes also took place more often in children under 5 years.
01 - 03 Oct 2015
European Society for Paediatric Endocrinology