ESPE2015 Poster Category 3 GH & IGF (68 abstracts)
Evaluation of the Facility of Use of a New GH Administration Device – Study DAGH2014
María José Rivero-Martín a , Ana Ontañón-Nasarre b , María José Alcázar-Villar a , America Carrasco-Torrents b , Ana Andrés-Rosado b & David Montes-Bentura a
aPediatrics Department, University Hospital of Fuenlabrada, Madrid, Spain; bPharmacy Department, University Hospital of Fuenlabrada, Madrid, Spain
Background: One of the limiting factors in adherence to GH therapy, is satisfaction with the administration device used.
Objective and hypotheses: With the emergence of a new biosmiliar GH (BGH) administration device, we will assess the simplicity, ease of use, management and pain perceived by the patients.
Method: Prospective through survey caregivers and children treated with BGH at least for 6 months. Signed informed consent was required. The questionnaire consists of 13 questions analysing four components: preparation, fixing of the dose, injection of the medication and maintenance. The perception of pain was measured by visual analogue scale expressed in numerical score.
Results: 23 patients/caregivers were interviewed; The dose average receiving was 0.78 mg/day. 60.8% were female. three patients did not complete the second questionnaire. 33.3% of the patients increased their participation in the self-administration of medication 89.5% of the patients prefer the new device and 10.5% the old device. On the pain scale, the average score for the old device was 2.1 (maximum: 6; minimum: 0); in 75% of patients, the score was <2. With the new device the average scale was 1.7 and 80% of patients scored < 2 (P: ns)
| Old device n=23 | New device n=20 | P | |
| General scale | Very easy 56.5% | Very easy 70% | ns |
| Preparation (three questions) | Very easy 55.1% | Very easy 73.3% | < 0.05 |
| Fixing dose (three questions) | Very easy 63.8% | Very easy 70% | ns |
| Injection (four questions) | Very easy 46.7% | Very easy 66.25% | < 0.05 |
| Maintenance (two questions) | Very easy 69.6% | Very easy 87.5% | ns |
Conclusion: The new device analysed has good acceptance among patients. Preparation and injection is easier with the new device. One of the most important effects is the increase in self-administration.
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