ESPE Abstracts (2015) 84 P-3-996

Endocrine Disruptor and Premature Puberty, is There Any Association?

Isolina Riaño-Galana,b, Adrian Estrada Menendezc, Ana Perez Lopezd, Mar Coto Fuentee, Margot Morane & Cristina Rodriguez-Dehlia


aPediatrics, Hospital San Agustin, Aviles, Spain; bCIBER de Epidemiología y Salud Pública, Ciberesp, Spain; cMIR MFyC, Hospital San Agustín, Aviles, Spain; dPediatrics, CDS Sabugo, Aviles, Spain, ePediatrics, CDS La Magdalena, Aviles, Spain


Background: Endocrine disruptors (ED) can alter endocrine function. ED have become a part of everyday life and are found among phytoestrogens, active ingredients in pharmaceuticals, and additives or contaminants in food, personal care products, cosmetics, plastics and textiles.

Objective: To describe cases of children with signs of early puberty who are exposed to ED.

Method: Observational study of patients affected of premature puberty. Detailed medical history about exposition to ED such as parabens or tea tree oil through creams, wipes or food was made.

Results: 12 girls who meet the criteria are described here. After removal of the product containing ED a regression of the signs of puberty was observed.

Conclusion: It is very important to conduct a detailed history of environmental exposure. There is much conflicting epidemiological evidence regarding the involvement of ED in premature puberty. But more use of the precautionary principle could reduce exposure early and avoid children’s health continued to be harmed.

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