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55th Annual ESPE

Paris, France
10 Sep 2016 - 12 Sep 2016

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Paris, France: 10-12 September 2016 Further information

Poster Presentations

Fat Metabolism and Obesity P2

hrp0086p2-p490 | Fat Metabolism and Obesity P2 | ESPE2016

Matsuda Index in Correlation with Clinical Indicators of Insulin Resistance in Children and Adolescents

Dikaiakou Eirini , Vlachopapadopoulou Elpis , Petychaki Foteini , Patinioti Ioanna , Anagnostou Elli , Karachaliou Feneli , Kafetzi Maria , Fotinou Aspasia , Michalacos Stefanos

Background: Obesity-related insulin resistance is present in obese children and Matsuda index is a method proposed to evaluate insulin resistance, using data obtained from the oral glucose tolerance test (OGTT).Objective and hypotheses: To investigate whether the clinical indicators of family history of obesity and/or Type II diabetes, acanthosis nigricans, and increased waist circumference are associated with insulin resistance, as calculated by the Mat...

hrp0086p2-p491 | Fat Metabolism and Obesity P2 | ESPE2016

Anthropometric, Biological and Imagistical Methods For Assessing the Cardiovascular Risk in Obese Children

Stroescu Ramona , Bizerea Teofana , Lesovici Maria , Marazan Monica , Marginean Otilia

Background: Pediatric obesity has increased worldwide over the last decades, being diagnosed at ever-younger ages.Objective and hypotheses: Evaluation of clinical and biological parameters and changes that occur in children with obesity; metabolic syndrome (MetS) identification in the studied groups; identification, evaluation, analysis and correlation of the adipogenic factors with the carotid intima media thickness (CIMT).Method:...

hrp0086p2-p492 | Fat Metabolism and Obesity P2 | ESPE2016

Trends of Nutrition of Ukrainian Children from Kharkiv Region: Tendency to Overweight, Dehydration, Impaired Social Adaptation

Chaychenko Tetyana , Rybka Olena , Georgievska Natalja , Buginskaya Nadija

Background: Diabetes, acute cardiovascular events and lifelong psychological problems reflect the obesity burden. Nutrition is a key point in prophylaxis and management of overweight and there is important to know trends of nutrition to build interventional strategies.Method: There are 1021 healthy lean (LH) and 372 obese (OW) adolescents aged 10–17 y.o. were survived with original questionnaire, which also included social and psychological (Beck-Yo...

hrp0086p2-p493 | Fat Metabolism and Obesity P2 | ESPE2016

Melanocortin-4 Receptor Gene Mutations in a Group of Turkish Obese Children and Adolescents

Tunc Selma , Demir Korcan , Tukun F Ajlan , Topal Cihan , Hazan Filiz , Saglam Burcu , Nalbantoglu Ozlem , Yildiz Melek , Ozkan Behzat

Background: Melanocortin-4 receptor (MC4R) mutations are the most common known cause of monogenic obesity but there is no data for Turkish children.Objective: To determine the prevalence of MC4R mutations in a group of Turkish morbid obese children and adolescents.Method: MC4R gene was sequenced in 47 consecutive morbidly obese children and adolescents (28 girls and 19 boys, aged 1–18 years) who presented dur...

hrp0086p2-p494 | Fat Metabolism and Obesity P2 | ESPE2016

Comparison between CDC (Centers for Disease Control and Prevention) and Italian Growth Charts in the Characterization of Pediatric Obesity

Pedicelli Stefania , Bizzarri Carla , Morino Giuseppe Stefano , Cappa Marco

Background: The use of international or local growth charts for the definition of pediatric obesity is still debated. Inappropriate reference standards may lead to under/over-estimation of the prevalence and consequently of the number of patients to be included in diagnostic work-up.Objective and hypotheses: To define the differences between patients considered obese according to either CDC or Italian growth charts.Method: A single...

hrp0086p2-p495 | Fat Metabolism and Obesity P2 | ESPE2016

The Cutoff Values of Indirect Indices for Measuring Insulin Resistance in Korean Children and Adolescents

Kim Jun Woo , Han Heon-Seok

Background: With the use of insulin resistance (IR) as a cause of metabolic syndrome (MetS), it is possible to screen the risk group of childhood MetS. Indirect index of IR can be estimated thru homeostasis model assessment (HOMA) of IR. Another index of triglyceride and glucose (TyG) were evaluated and equally effective in some adult studies. However, we do not have consistent prevalence rate and percentile distribution of MOMA-IR and TyG index in children and adolescent popu...

hrp0086p2-p496 | Fat Metabolism and Obesity P2 | ESPE2016

Intensive Exercise Intervention for Long-term Adolescent and Young Adult Survivors of Oncology-Related Cranial Insult: A Pilot Study

Rath Shoshana , Long Treya M , Bear Natasha , Graham Kerrie , Atkinson Helen , Naylor Lousie , Cole Catherine , Gottardo Nick , Choong Catherine

Background: Survivors of childhood cancer are at increased risk of cardiovascular morbidity and mortality in later life. Although the brain is known to be involved in control of metabolic functions including appetite regulation and energy expenditure (1), little data are available relating to the risk of metabolic dysfunction secondary to cerebral injury. Several studies have attempted to investigate the impact of exercise on physical and psychosocial parameters in survivors o...

hrp0086p2-p497 | Fat Metabolism and Obesity P2 | ESPE2016

Cardiometabolic Effect of Sugar-Sweetened Beverages Reduction in Obese Children

Galhardo Julia , Diamantino Catarina , Alonso Anabela , Lopes Lurdes

Background: The excessive consumption of sucrose, primarily used in sweetened beverages, has been considered an important inducer of cardiometabolic diseases. Besides the association between metabolic syndrome and fructose found in animal models, literature is lacking prospective studies in humans, especially in paediatric ages.Objective and hypotheses: We assessed the effect of sugar-sweetened beverages reduction on markers of metabolic syndrome in obes...

hrp0086p2-p498 | Fat Metabolism and Obesity P2 | ESPE2016

A Comprehensive and Multidisciplinary Management Plan is Extremely Effective at Reducing the Prevalence of Overweight and Obesity in Childhood and Adolescence

Genitsaridi Sofia , Karampatsou Sofia , Papageorgiou Ifigeneia , Papadopoulos Georgios , Farakla Ioanna , Koui Eleni , Georgiou Alexandra , Romas Stamatis , Terzioglou Eleni , Papathanasiou Chryssanthi , Kassari Penio , Giannios Christos , Nicolaides Nicolas C , Manios Yannis , Charmandari Evangelia

Background: Obesity in childhood and adolescence represents a major health problem of our century, and accounts for a significant increase in morbidity and mortality in adulthood. In Greece, more than 30–35% of children and adolescents are overweight or obese.Objective and hypotheses: To investigate the effectiveness of a comprehensive and personalized multidisciplinary management plan in reducing the prevalence of overweight and obesity in childhoo...

hrp0086p2-p499 | Fat Metabolism and Obesity P2 | ESPE2016

Multidisciplinary Care Management of Pediatric Obesity and Factors Associated with Better Outcomes

Thibault Helene , Carriere Caroline , Cabaussel Cassandre , Bader C , Barberger-Gateau Pascale , Barat Pascal

Background: RePPOP Aquitaine (network of prevention and treatment of pediatric obesity in southwest France) has developed a multidisciplinary approach to treat childhood obesity based on multicomponent lifestyle interventions and family-based actions.Objective and hypotheses: This study assessed the impact of the care management proposed by RePPOP Aquitaine and investigated factors associated with better outcomes.Method: The impact...

hrp0086p2-p500 | Fat Metabolism and Obesity P2 | ESPE2016

Prevalence and Characteristics of Polycystic Ovary Syndrome in Obese Adolescents

Ybarra Marina , Franco Ruth , Cominato Louise , Sampaio Raissa , Sucena Silvia , Damiani Durval

Background: Polycystic ovary syndrome (PCOS) in adolescence has a challenging diagnosis and therefore has raised intense discussions. Its prevalence in childbearing age women ranges from 5 to 10%. However, the prevalence in obese adolescents has not yet been reported. Besides, the relationship of PCOS with metabolic and cardiovascular disorders in this specific population has not been established.Objective and hypotheses: We aimed to assess the prevalenc...

hrp0086p2-p501 | Fat Metabolism and Obesity P2 | ESPE2016

Efficacy of the Treatment for Childhood Obesity in Specialist Care: Age Over 10 Years at Baseline and Acanthosis Nigricans Predict a Worse Outcome

Valle Marketta Dalla , Laatikainen Tiina , Nykanen Paivi , Jaaskelainen Jarmo

Background: Treatment of pediatric obesity is challenging and especially the long-term outcome has been modest in many previous studies.Objective and hypotheses: We wanted to evaluate the efficacy of obesity treatment in specialist care and to find out factors, which have a major impact on the outcome.Methods: A total of 654 children (302 girls) aged 2–18 years treated for obesity between 2005 and 2012 in three specialist clin...

hrp0086p2-p502 | Fat Metabolism and Obesity P2 | ESPE2016

Metabolic Syndrome in Prepubertal Obese Children: Inclusion of the Triglyceride/Hdl Ratio as an Alternative Diagnostic Criterion

Boquete Carla , Jesica Baran , Yuseff Fernanda Alvarez , Suarez Martha , Fideleff Gabriel , Azaretzky Miriam , Aranguren Marcela , Fusero Mariela , Ruibal Gabriela , Fideleff Hugo , Boquete Hugo

Background: Although a large number of publications show a high prevalence of Metabolic Syndrome (MS) during childhood, to date, there is no uniform definition for evaluating this condition in children and adolescents. In the pediatric population, there are difficulties for characterizing this condition and the various criteria used might lead to underdiagnosis. In recent years, the triglycerides/HDL (TG/HDL) ratio has been proposed as a new marker.Objec...

hrp0086p2-p503 | Fat Metabolism and Obesity P2 | ESPE2016

The relationship between Subclinical Hypothyroidism and Iodine Deficiency, Serum Leptin Levels and Metabolic Syndrome in Obese Children

Dundar Bumin N. , Tanrısever Ozgur , Catli Gonul , Kocyigit Cemil , Can Penbe S. , Pirgon Ozgur

Background: Subclinical hypothyroidism (SH) has an incidence of 3.2–22.2% in obese children. The etiology of increased prevalence of SH is still unclear in obese individuals.Objective and hypotheses: To investigate the relation of SH with iodine deficiency, serum leptin levels and metabolic parameters in obese children and adolescents.Method: One hundred and fifty nine obese and 54 healthy children and adolescents were include...

hrp0086p2-p504 | Fat Metabolism and Obesity P2 | ESPE2016

Analysis of Circulating miRNAs in Obese Children Born Small for Gestational Age

Faienza Maria Felicia , Marzano Flaviana , Inzaghi Elena , Annese Anita , Caratozzolo Mariano Francesco , D'Erchia Annamaria , Chiara Matteo , Horner David , Sbisa Elisabetta , Cavallo Luciano , Pesole Graziano , Tullo Apollonia , Cianfarani Stefano

Background: Children born small for gestational age (SGA) are at increased risk of coronary heart disease and type 2 diabetes in adulthood, due to reprogramming of endocrine and metabolic functions. Dysregulation of specific miRNAs in response to genetic and environmental factors contribute to aberrant gene expression patterns underlying metabolic dysfunction.Objective and hypotheses: We aimed to identify miRNAs associated with increased risk of obesity ...

hrp0086p2-p505 | Fat Metabolism and Obesity P2 | ESPE2016

Irisin and Abdominal Obesity in Preschool Age

Lateva Mina , Popova Ralitsa , Bocheva Yana , Galcheva Sonya , Chervenkov Trifon , Iotova Violeta

Background: Since its discovery in 2012 the ‘browining’ adipokine irisin is known to lead to increased thermogenesis and energy expenditure. Studies in children are scarce, with results similar to most studies in adults.Objective and hypotheses: To establish a link between total and abdominal fat mass, physical activity and irisin in preschool age.Method: Height, weight and waist circumference (WC) of 40 healthy pre-puber...

hrp0086p2-p506 | Fat Metabolism and Obesity P2 | ESPE2016

Long Term Outcomes after Hospital Based, Life-Style Weight Loss Intervention During Childhood

Candler Toby , Wei Christina , Crowne Elizabeth , Shield Julian

Background: Weight loss interventions for obesity have shown variable short-term effects in adolescents and children, but data on longer-term benefits are sparse.Aim: To describe longer-term impact of lifestyle weight loss interventions in adolescent obesity.Method: Obese subjects previously underwent lifestyle weight loss interventions at a hospital-based clinic were invited to participate in metabolic re-assessment. Outcome measu...

hrp0086p2-p507 | Fat Metabolism and Obesity P2 | ESPE2016

Implications of Insulin Resistance in Obese and Overweight Children: A Cohort Analysis

Yadav Sangita , L Kaviya , Kaushik Smita , Mantan Mukta

Background: Rising trend of both type 2 diabetes and obesity observed in adult and pediatric Indian population. Imperative to evaluate insulin resistance among overweight and obese children.Objective and hypotheses: To examine insulin resistance and associated co-morbidities in overweight and obese children.Method: Hospital based Cross sectional study 50 overweight and obese 5–18 years (BMI ≥90th centile WHO Charts). Wei...

hrp0086p2-p508 | Fat Metabolism and Obesity P2 | ESPE2016

Effects of Highly Mineralized Water on Weight and Metabolism – A Randomized Controlled Blinded Trial in a Pediatric Hospital Staff

l'Allemand-Jander Dagmar , Miller Patrick , Laimbacher Josef

Background: The role of calcium in cardiovascular and metabolic risk is controversial.Objective and hypotheses: To examine the effect of highly mineralized natural water in lowering body weight, blood pressure, cholesterol and blood sugar and to assess health behaviour of the staff of a pediatric hospital.Method: Out of 650 pediatric hospital staff members, we examined 161 healthy subjects, aged 28–64 years, 77.5% women, two d...

hrp0086p2-p509 | Fat Metabolism and Obesity P2 | ESPE2016

Which Marker is the Most Reliable One for the Detection of NAFLD in Outpatient Clinic?

Ozsu Elif , Yazicioglu Bahadir

Background: Non-alcoholic fatty liver disease (NAFLD) has become a public health issue because its incidence increased threefold during the last 3 decades among children and adolescents. Although liver biopsy is the gold standard to determine NAFLD, its applicability is low in childhood. Thus, some noninvasive markers are being used more commonly.Objective and hypotheses: We aimed to find the most reliable marker to detect NAFLD in routine examination.</...

hrp0086p2-p510 | Fat Metabolism and Obesity P2 | ESPE2016

Nonalcoholic Fatty Liver Disease: Evolution after 1 year of Follow-Up with Different Therapies

Mata Maria Angeles Santos , Viseras Irene Fernandez , Ruiz Jose Pedro Novalbos

Background: Fatty liver disease is diagnosed increasingly in obese children, which pathophysiology remains unexplained. Risk factors as insulin resistance, evolution of steatosis and hypertriglyceridemia, should be taken into consideration in its development.Objective and hypotheses: To analyse the prevalence of hepatic steatosis identified by ultrasound, as well as features and anthropometric data in our population divided into 2 groups: with steatosis ...

hrp0086p2-p511 | Fat Metabolism and Obesity P2 | ESPE2016

Lifestyle Survey of Doctors, Medical Residents and Medical Students in Latvia

Gailite Jurgita , Urbane Urzula Nora , Salijuma Eliza , Arnicane Ligita , Terjajeva Ludmila , Erts Renars , Dzivite-Krisane Iveta , Gardovska Dace

Background: According to World Health Organization, balanced diet and regular physical activity is the key to maintaining a healthy lifestyle.Objective and hypotheses: The aim of this study was to evaluate lifestyle habits of the healthcare personnel in Latvia.Method: Data about eating habits, physical activity, duration of sleep and other lifestyle factors were collected from medical students, medical residents and specialized doc...

hrp0086p2-p512 | Fat Metabolism and Obesity P2 | ESPE2016

Weight Status in Children at 8 Years: A Prospective Cohort Study

Riano-Galan Isolina , Cristina Rodriguez-Dehli Ana , Olaya-Vazquez Ines , Fernandez-Somoano Ana , Tardon Adonina

Background: Prevalence of childhood obesity represents a major public health concern, given the tracking of body weight from childhood to adult age and its health sequelae.Objective: To describe prevalence of overweight (OW) and obesity (OB) in children at 8 years and investigate the relationship with pre-pregnancy maternal weight and weight status at 4 years.Methods: 485 pregnant mothers recruited between 2004 and 2007 and 409 chi...

hrp0086p2-p513 | Fat Metabolism and Obesity P2 | ESPE2016

Low Birth Weight is not Associated with Increased Risk of Metabolic Syndrome in Obese Children and Adolescents

Inzaghi Elena , Fintini Danilo , Baldini Ferroli Barbara , Grossi Armando , Pedicelli Stefania , Bizzarri Carla , Fiori Rossana , Spadoni Gianluigi , Scire Giuseppe , Cappa Marco , Cianfarani Stefano

Background: Children born small for gestational age (SGA) are at risk for metabolic syndrome (MetS) as adults and show a higher prevalence of MetS components.Objective and hypotheses: To define the association between low birth weight and the presence of MetS in a cohort of obese Italian children and adolescents.Method: The presence of MetS was studied in a cohort of obese (BMI >90th centile) children and adolescents consisting...

hrp0086p2-p514 | Fat Metabolism and Obesity P2 | ESPE2016

Prader Willi Syndrome in Brazil: 6 months Follow-up in a Reference Center

Ito Simone , Passone Caroline , Rocha Ruth , Dichtchekenian Vae , Kupperman Hilton , Damiani Durval

Background: Prader–Willi syndrome (PWS) patients have been followed in our country in different ways but without a reference center. In January 2015, we started a PWS reference center in Sao Paulo University to promote a better care for patients and families and to support them with a multidisciplinary team, including pediatric endocrinologist, dietician, nurses, neurologist specialized in sleep disorders and otorhinolaringologist.Method: Forty-two ...

hrp0086p2-p515 | Fat Metabolism and Obesity P2 | ESPE2016

Early Blood Pressure Abnormalities Related to Cardiovascular Risk in Obese Children and Adolescents

Herraiz Gastesi Gonzalo , Pilar Samper Villagrasa Maria , Moreno Aznar Luis , Leis Trabazo Rosaura , Aguilera Garcia Concepcion , Gil Hernandez Angel , Gil-Campos Mercedes , Maria Garagorri Otero Jesus , Gloria Bueno Lozano Maria

Background: Emerging data suggest that ambulatory blood pressure (BP) monitoring for 24 h may be efficient in the diagnosis of hypertension in adults, children and adolescents. Additionally, in adults, it may predict the existence of some early BP abnormalities related to cardiovascular risk: (a) elevated BP load (>25%) and (b) non-dipping (BP decrease in night-time <10%).Objective and hypotheses: To evaluate the presence of early BP abnormalitie...

hrp0086p2-p516 | Fat Metabolism and Obesity P2 | ESPE2016

4G Polymorphism of Plasminogen Activator Inhibitor-1 (PAI-1), PAI-1 Plasma Levels, and Lipid Profiles in Overweight/Obese Children and Adolescents

Karabouta Zacharoula , Makedou Areti , Papandreou Dimitrios , Argiriou Anagnostis , Xanthopoulou Helen , Rousso Israel , Athanassiadou-Piperopoulou Fani

Background: Studies have shown that PAI-1 4G polymorphism is related to increased plasma PAI-1 levels, obesity, dyslipidaemia and cardiovascular disease (CVD) in adults. Few studies have explored that relationship in overweight/obese (Ow/Ob) children/adolescents.Objective and hypotheses: We investigated the relation between plasma PAI-1 levels, PAI-1 4g polymorphisms and lipid profiles in Ow/Ob children/ adolescents compared with healthy normal ...

hrp0086p2-p517 | Fat Metabolism and Obesity P2 | ESPE2016

Polycystic Ovarian Syndrome in a Population of Obese Adolescents

Elowe-Gruau Eglantine , Ameti Adelina , Gonzalez Elena , Vial Yvan , Renteria Saira-Christine , Bouthors Therese , Borloz Sylvie , Puder Jardena , Stoppa-Vaucher Sophie , Phan-Hug Franziska , Dwyer Andrew , Hauschild Michael , Pitteloud Nelly

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disease among women of reproductive age with a prevalence of about 8% according to the Androgen Excess Society (AES) criteria. The pathophysiology of PCOS is not well understood and it is associated with a high prevalence of metabolic disorders. During puberty, irregular menses and acne are common, thus making the diagnosis of PCOS in adolescence challenging.Objective and hypothe...

hrp0086p2-p518 | Fat Metabolism and Obesity P2 | ESPE2016

Vitamin D Deficiency in Obese Children and the Relationship with Insulin Resistance and Metabolic Syndrome

Fernandez Viseras Irene , Angeles Santos Mata Maria , Lechuga Sancho Alfonso , Pedro Novalbos Ruiz Jose , Jose Macias Lopez Francisco

Background: Vitamin D is a pleiotropic hormone the deficiency of which is related with extraskeletal manifestations such as insulin resistance and cardiovascular risk disease.Objective and hypotheses: To investigate the levels of VitaminD in a sample of children with obesity and to evaluate the relationship between carbohydrate metabolism and metabolic syndrome (MS).Method: In this prospective cross-sectional study, 189 children ag...

hrp0086p2-p519 | Fat Metabolism and Obesity P2 | ESPE2016

Dietary Habits of Children and Adolescents Attending an Out-Patient Clinic for the Prevention and Management of Overweight and Obesity in Greece

Georgiou Alexandra , Karampatsou Sophia , Genitsaridi Sophia , Nikolaou Mihaela , Farakla Ioanna , Papadopoulos Georgios , Giannios Christos , Nicolaides Nicolas , Papageorgiou Ifigenia , Mpoleti Olga , Koui Eleni , Tsoutsoulopoulou Konstantina , Manios Yannis , Charmandari Evangelia

Background: Obesity in childhood and adolescence represents a major health problem and its management requires a multidisciplinary approach.Objective and hypotheses: To assess the main eating habits of children and adolescents attending an Out-patient Clinic for the Prevention and Management of Overweight and Obesity in Greece, as recorded before implementing any intervention.Method: We studied 1005 children and adolescents [age ra...

hrp0086p2-p520 | Fat Metabolism and Obesity P2 | ESPE2016

Preliminary Findings on Nutrition Care Competence in Health Care Professionals Using a Standardized Questionnaire NUTCOMP Korean Version

Kim Kieun , Kim Gyeong-Mi , Jeong Mi-Yong , Kim Yanghyeon , Lee Kyu-Rae , Kim Sun-Hyeon , Baik Seolhyang , Shin Hyejeong

Background: It is well known that obesity, diabetes or chronic disease are related with nutrition. However it has not been known whether health providers have concepts or competence about counseling of nutritional support in clinical practice basis. There is rare of information about differences among types of profession jobs.Objective and hypotheses: We investigated a survey with standardized questionnaire tool among different types of profession jobs d...

hrp0086p2-p521 | Fat Metabolism and Obesity P2 | ESPE2016

Construction of Remote Monitoring System of Children with Tall or Short Stature and Overweight or Poor Weight Gain from the Elementary School Health Checkup Data

Motoki Takanori , Miyata Ichiro , Kariyazaki Maki , Tsuru Satoko

Background: A school nurse and a school physician do screening of short stature and overweight by height and weight measured in the school health examination. Furthermore, in the municipality, practitioners are doing medical examination to preventing for children’s unhealthy lifestyle to applicants. However the pediatric endocrinologists of the ward sometimes examine the first visit patients with short stature, highly obese or type 2 diabete patients who have passed a few...

hrp0086p2-p522 | Fat Metabolism and Obesity P2 | ESPE2016

The Effect of Demographic and Lifestyle Factors on One-year BMI Increments in 776 Norwegian Children Aged 6–15 Years

Kristiansen Hege , Roelants Mathieu , Bjerknes Robert , Juliusson Petur

Background: There is limited information on the ability of demographic or lifestyle factors to predict short term changes in weight status during childhood.Objective and hypotheses: To study the effect of parental (educational level, BMI status and perception of child’s weight status) and childhood factors (eating habits, sedentary behaviour and physical activity), on 1-year BMI increments by the use of BMI, BMI SDS and BMI SDS conditional gain....

hrp0086p2-p523 | Fat Metabolism and Obesity P2 | ESPE2016

Body Image Perception Changes in Obese and Lean Children

Viazava Liudmila , Solntsava Anzhalika , Sukalo Alexander

Background: Body image (BI) is subjective picture of one’s own physical appearance established both by self-observation and by noting the reactions of others. Different BI scales used for screening of the Binge Eating symptoms that strongly linked to obesity.Objective and hypotheses: We supposed to get differences in the own body image perception in overweight and lean children.Method: BI questionnaire (BIQ) and own body satis...

hrp0086p2-p524 | Fat Metabolism and Obesity P2 | ESPE2016

Non-Alcoholic Hepatic Steatosis in Obese Children and the Relationship with Insulin Resistance

Fernandez Viseras Irene , Angeles Santos Mata Maria , Jose Macias Lopez Francisco

Background: Hepatic steatosis is common in obese children. The pathophysiology remains unexplained but it is known that insulin resistance and hypertrilycerdemia are involved in its development.Objective and hypotheses: To analyse the prevalence of hepatic steatosis identified by ultrasound, as well as features and anthropometric data in our population divided into two groups: (with steatosis and without steatosis) to assess the risk factors.<p class...

hrp0086p2-p525 | Fat Metabolism and Obesity P2 | ESPE2016

Prevalence of Melanocortin 4 Receptor Mutations in Turkish Obese Children

Aykut Ayca , Ozen Samim , Goksen Damla , Onay Huseyin , Atik Tahir , Darcan Şukran , Ozkinay Ferda

Background: The melanocortin-4-receptor gene (MC4R) is a key regulator of energy homeostasis, food intake and body weight which has intensively been analyzed in molecular genetic obesity research. MC4R dysfunction in humans causes hyperphagia, impaired satiety and obesity.Objective and hypotheses: To identify MC4R mutations prevelance in Turkish obese children and adolescents.Method: Ninenty three pediatric and adolescent patients ...

hrp0086p2-p526 | Fat Metabolism and Obesity P2 | ESPE2016

Prevalence of Overweight and Obesity in Children and Adolescents in Izmir, Western Turkey

Nalbantoglu Ozlem , Ozkan Behzat , Tunc Selma , Apa Hursit

Background: Although the highest prevelance rates of childhood obesity and overweihgt have been observed in developed countries, its prevelance is reported to be increasing in developing countries as well. Prevelance of obesity and overweight in different regions of Turkey ranges between 1.6–7.8 and 9.9–17.6 respectively.Objective and hypotheses: The purpose of this study was to investigate the prevelance of obesity and overweight among student...

hrp0086p2-p527 | Fat Metabolism and Obesity P2 | ESPE2016

Arbitrary Cutoffs Lead to Underestimation of Metabolic Abnormalities in Obese Children: The Value of Age- and Sex-adjusted Normative Values

Carlier Gonod Adele , Azar Ahlam , Lecomte Nathalie , Amouyal Perrod Melanie , Prevot Manon , Jacques Adeline , Guilmin Crepon Sophie , Claude Carel Jean

Background: Metabolic syndrome and insulin resistance are well recognized in adult obesity. Their criteria and prevalence and are still controversial in children.Objective and hypotheses: To evaluate the prevalence and natural history of clinical and biological parameters of the metabolic syndrome in a pediatric cohort of obese subjects. To identify metabolically healthy subjects and the persistence of this phenotype over time.Meth...

hrp0086p2-p528 | Fat Metabolism and Obesity P2 | ESPE2016

Breasts Diseases in Adolescent Girls With Obesity

Gumeniuk Olga , Chernenkov Yuriy

Background: Obesity is associated with increased risks of the disease of the reproductive organs (including breasts). Several studies mentioned correlation between obesity and increased risks for breast cancer.Objective and hypotheses: To study the frequency and peculiarities of breasts diseases in adolescent girls with obesity.Method: The study included 2369 adolescent girls (aged 11–19 years). Gils were subjected to the clin...

hrp0086p2-p529 | Fat Metabolism and Obesity P2 | ESPE2016

Insulin Resistance Correlates to Cognitive Fatigue Dimensions in Non-diabetic Obese Children

Barat Pascal , Meiffred Marie-Claire , Brossaud Julie , Corcuff Jean-Benoit , Thibault Helene , Capuron Lucile

Background: Alterations in endocrine functions and low-grade systemic inflammation represent fundamental characteristics of obesity. These biological systems have been repeatedly linked to fatigue symptoms.Objective and hypotheses: The aim of the study was to assess the relationship between fatigue symptoms and metabolic/inflammatory markers in a sample of non-diabetic obese children.Method: The study was conducted in 41 obese (med...

hrp0086p2-p530 | Fat Metabolism and Obesity P2 | ESPE2016

Vascular Endothelial Growth Factor as The Predictor Microangiopathy in Obese and Diabetic Children

Ben-Skowronek Iwona , Kapczuk Iga , Stapor Natalia , Banecka Bozena

Background: Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis. It is part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. Serum concentration of VEGF is high in bronchial asthma and diabetes mellitus. Overexpression of VEGF can cause vascular disease in the retina of the eye and other parts of the body.Objective and hypotheses: The...

hrp0086p2-p531 | Fat Metabolism and Obesity P2 | ESPE2016

Associations of Serum 25-Hydroxyvitamin D and Components of the Metabolic Syndrome in an Egyptian Cohort

Ibrahim Amany , Meabed Mohamed , El Mosallamy Nevin , Abo El Hassan Gehad

Background: Vitamin D deficiency may be associated with increased risk of metabolic syndrome.Objective and hypotheses: We aimed to assess the relation between 25-hydroxyvitamin D (25(OH) D) with the different metabolic syndrome components in overweight and obese subjects.Method: Ninety eight subjects (≥85th percentile for age and sex) recruited from the Diabetes, Endocrine & Metabolic Paediatrics Unit (DEMPU), Cairo Unive...

hrp0086p2-p532 | Fat Metabolism and Obesity P2 | ESPE2016

Retrospective Evaluation of the Efficiency of Metformin Therapy in Obese Children with Insulin Resistance

Cicek Gizem , Abaci Ayhan , Tuhan Hale , Demir Korcan , Bober Ece

Background: Prevalence of obesity has been rising throughout the world. Dyslipidemia, hypertension, insulin resistance, and type 2 diabetes mellitus (DMT2) (metabolic syndrome) are frequently observed serious complications of obesity. The primary approach in the treatment of metabolic syndrome is improving insulin resistance. Metformin is considered as an option for treatment in children with insulin resistance. During the last decade, numerous studies have been published demo...

hrp0086p2-p533 | Fat Metabolism and Obesity P2 | ESPE2016

Parental Obesity can Trigger Obesity in Children

Koohmanaee Shahin , Dalili Setila

Background: Obesity is a disease (2) which is associated with increased morbidity and mortality rate (3) and needs extensive preventive procedures and effective interferences. Children with obese parent are in danger of becoming obese in their adolescence and adulthood even when trying to keep their weight stable.Objective and hypotheses: We aimed to investigate whether parental obesity can trigger obesity in children or not.Method...

hrp0086p2-p534 | Fat Metabolism and Obesity P2 | ESPE2016

Value of BMI-SDS, Waist Circumference-SDS and Waist-to-Height Ratio in the Identification of Obese Children and Adolescents at an Increased Risk for Cardio-Metabolic Complications

Kovac Jernej , Pavlic Petra , Perdih Brigita , Kotnik Primoz

Background: Determination of obese children/adolescents at an increased risk of cardio-metabolic complications is of paramount significance for early intervention.Objective and hypotheses: To determine the value of simple anthropometric measures of obesity (BMI-SDS, waist circumference (WC)-SDS, waist-to-height ratio (WHR)) in the determination of individuals at an increased risk for selected cardio-metabolic complications (impaired glucose metabolism, d...

hrp0086p2-p535 | Fat Metabolism and Obesity P2 | ESPE2016

Thyroid Dysfunction and Formation of Dyslipoproteiniaemias: Gender Differences in Children with Obesity

Budreiko Olena , Shushlyapina Olena , Kosovtsova Anna , Nikitina Larisa

Background: Thyroid dysfunction plays an important role in formation of dyslipidemia during obesity while thyroid pathology (TP) is one of the most common endocrinopathies associated with obesity. Among adults existence of gender differences has been proven in formation of a dyslipoproteiniaemias and thyropathies; the presence of such changes in obese children requires clarification.Objective and hypotheses: To explore the details of blood lipids in chil...

hrp0086p2-p536 | Fat Metabolism and Obesity P2 | ESPE2016

How Early is Insulin Resistance in Our Pediatric Population with Metabolic Syndrome

Yadav Sangita , Kaviya L , Mantan Mukta , Kaushik Smita

Background: Childhood critical period for onset/continuity of obesity with development of significant clinical and metabolic changes, impairing health in adulthood. Metabolic syndrome on rise both in adult and pediatric obese Indian population. Development of impaired glucose tolerance and progress to insulin resistance and other metabolic alterations like hypertension, dyslipidemia, Non alcoholic fatty liver disease are important.Aim: Evaluate insulin r...

hrp0086p2-p537 | Fat Metabolism and Obesity P2 | ESPE2016

Insulin Resistance for Adolescents with Obesity in Latvia

Gailite Jurgita , Lubina Olga , Salijuma Eliza , Napituhina Ilze , Agadzanjana Karina , Stundzane Irena , Kirillova Inara , Lauga-Tunina Una , Vetra Anita , Dzivite-Krisane Iveta

Background: Insulin resistance for adolescents with obesity takes up a central role in the development of metabolic comorbidities, especially of type 2 diabetes.Objective and hypotheses: The aim of this study was to compare anthropometric data, apolipoprotein B, glucose, insulin level and HOMA-IR coefficien between genders.Method: Data about anthropometric parameters, blood samples, 6-min walk test (6MWT), eating habits and physica...

hrp0086p2-p538 | Fat Metabolism and Obesity P2 | ESPE2016

Parental Obesity can Trigger Obesity in Children

Koohmanaee Shahin , Dalili Setila

Background: Obesity is a disease which is associated with increased morbidity and mortality rate and needs extensive preventive procedures and effective interferences. Children with obese parent are in danger of becoming obese in their adolescence and adulthood even when trying to keep their weight stable.Objective and hypotheses: We aimed to investigate whether parental obesity can trigger obesity in children or not.Method: This i...

hrp0086p2-p539 | Fat Metabolism and Obesity P2 | ESPE2016

Cerebrotendinous Xanthomatosis: A Case Report of Rare Lipid Storage Disorder

Gupta Deepak Chand , Syed Mohd. Razi , Gupta Abhinav Kumar , Gupta Keshav Kumar

Background: Cerebrotendinous xanthomatosis (CTX) is a very rare autosomal recessive lipid storage disorder affecting bile acid biosynthesis. It is manifested by subtle neurological and non-neurological symptoms due to abnormal tissue lipid deposition. Usually, the diagnosis is delayed but early diagnosis and replacement therapy can prevent devastating neurological sequelae.Objective and hypotheses: To diagnose and manage a case of cerebrotendinous xantho...

hrp0086p2-p540 | Fat Metabolism and Obesity P2 | ESPE2016

Analysing Child Obesity Risk Factors: Adenotonsillectomy

Paul Corina , Velea Puiu Iulian , Mogoi Mirela

Background: Adenotonsillectomy is one of the most common surgical procedure performed in children in Romania. Child obesity also, seems to follow the same trend of increasing prevalence as worldwide.Objective and hypotheses: To determine if there is a relationship between adenotonsillectomy and postoperative weight gain in children.Method: The retrospective four year study included 235 children. After applying the exclusion criteri...

hrp0086p2-p541 | Fat Metabolism and Obesity P2 | ESPE2016

Non-Medicament Treatment of Severe Obese Children, Using the One-Year Courses

Zagrebaeva Olga , Solntsava Anzhalika , Yemelyantsava Tatsiana

Background: It is hard to treat severe obese children only with diet and physical activity, psychological interventions are need.Objective and hypotheses: To examine the differences between courses of non-medicament treatment of severe obese children.Method: We examined 32 pubertal severe obese children BMI 31.2±0.8 kg/m2, 13.5±0.3 years. The newel (in Belarus) course of non-medicament treatment of obesity (die...

hrp0086p2-p542 | Fat Metabolism and Obesity P2 | ESPE2016

Obstructive Sleep Apnea Syndrome in Early Childhood: Case Report

Rachid Ludmilla , Queiroz Edjane , Cominato Louise , Rocha Ruth , Ybarra Marina , Steinmetz Leandra , Semer Beatriz , Menezes Filho Hamilton , Damiani Durval

Background: Obstructive sleep apnea syndrome (OSAS) in children is a common medical disorder, often associated with adenoid and tonsil hypertrophy. The prevalence of OSAS has been increasing due to alarming rates of obesity in childhood. This is a very concerning subject since there is a higher risk of cardiovascular outcomes in patients with elevated BMI and OSAS.Objective and hypotheses: The aim of this study is to report a hazardous case regarding chi...

hrp0086p2-p543 | Fat Metabolism and Obesity P2 | ESPE2016

25-Hydroxyvitamin D Concentrations in Pubertal Children with Obesity

Yordanova Desislava , Stefanova Elisaveta , Kazakova Krasimira , Todorova Zdravka , Dimitrova Mihaela

Background: The prevalence of childhood obesity has been rapidly increasing worldwide and the last report of World Health Organisation define it as epidemic and one of the most serious global public health challenges for the 21st century. Obese children and adolescents are at an increased risk of developing various health problems including type 2 diabetes mellitus, hypertension, osteoarthritis, cardiovascular disease. Obesity is a risk factor for vitamin D deficiency. Vitamin...

hrp0086p2-p544 | Fat Metabolism and Obesity P2 | ESPE2016

Management Preschool Children of Prader–Willi Syndrome

Bajraktarevic Adnan , Uzicanin Sajra , Krupic Ferid , Abduzaimovic Alisa , Beslagic Emina , Suljevic Ismet , Masala Almir

Background: The symptoms of Prader–Willi syndrome are likely due to dysfunction of a portion of the brain called the hypothalamus. Children of Prader–Willi syndrome want to eat constantly because they never feel full hyperphagia and usually have trouble controlling their weight.Objective and hypotheses: Genetic syndromes with obesity and delayed altered intellectual development as a major part of the phenotype include Prader–Willi syndrome...

hrp0086p2-p545 | Fat Metabolism and Obesity P2 | ESPE2016

Prevalence of Acanthosis Nigricans and Related Factors in Iranian Obese Children

Sayarifard Fatemeh , Allahverdi Bahar , Sayarifard Azadeh , Ipakchi Sara , Motlaghzadeh Yasaman

Background: Obesity is one of health problems worldwide. Acanthosis nigricans has been considered as a symptom of hyperinsulinemia in children.Objective and hypotheses: We designed this study to evaluate and compare clinical and laboratory findings in Iranian obese children with and without acanthosis nigricans.Material: Seventy-one obese children enrolled. Fasting blood sugar, total cholesterol, triglycerides, alanine aminotransfe...