ESPE Abstracts (2016) 86 P-P1-475

Reduction of Body Mass and Change in Body Composition of the Participants of the PoZdro! - Programme for Prevention of Diabetes and Civilisation Diseases by Medicover Foundation - Preliminary Results, after the First Year of Interventions

Hanna Magnuszewskaa, Tomasz Anyszeka, Michal Brzezinskia, Monika Lechc, Piotr Soszynskia, Jacek Walewskic, Kamila Szarejkob, Marcin Radziwillb, Malgorzata Mysliwiecd,a & Leszek Czupryniake,a

aScientific Counsil of Medicover Foundation, Warsaw, Poland; bMedicover Foundation, Warsaw, Poland; cMedicover, Warsaw, Poland; dDepartment of Paediatrics, Diabetology and Endocrinology, Medical University of Gdansk, Gdansk, Poland; eDepartment of Gastroenterology and Metabolic Diseases, Banacha Street Hospital in Warsaw, Warsaw, Poland

Background: Lifestyle interventions are basic tool to treat obesity in the youth. They prevent from civilisation diseases. Globally, there are many programmes including regular meetings with dieticians, exercise specialists, and others. Results are promising, although there’s no consensus regarding one model of recommended diet, exercise’s intensity and frequency of interventions.

Objective and hypotheses: Assessment of preliminary results of ‘PoZdro!’. Analysis of factors affecting reduction of body mass and change in body composition in programme participants.

Method: 870 adolescents with excessive body mass (BMI ≥90 pc), age 13.8±0.7 years, 388 (44.6%) girls, 482 (55.4%) boys were included in a two-year programme of lifestyle interventions. During the first year 6 interventions were realised, everyone included meeting with physician, dietician, exercise specialist, and psychologist, at six-week intervals at the beginning, and at three-month intervals in later period. Healthy diet, especially reduction of simple carbohydrates and regular exercises of moderate intensity were recommended. Laboratory tests (OGTT, HOMA-IR, lipid parameters, ALT) were performed at the beginning. Anthropometric parameters (height, mass, WHR, body composition) were evaluated during each intervention.

Results: 870 participants started programme, 125 (14.4%) have already had six interventions. Significant decrease in BMI and WHR was observed at each visit. BMI fell down from 26.77±3.06 to 25.97±3.06 at six visit, and WHR from 0.96±2.49 to 0.87±0.07. Reduction of body fat percentage (BFM (%)) from 30.07±7.67 to 27.5±7.84 and absolute body fat mass (BFM (kg)) from 22.79±7.75 to 21±7.15, increase in absolute muscle mass (MM (kg)) from 49.9 to 52.16±8.71 were stated. Decrease in BMI centile (pcBMI) at the last visit was observed in 311 (49.9%) participants, no changes in 175 (28.1%), and increase in 137 (22%). Change in BMI correlated inversely with baseline pcBMI (r=−0.102, P=0.011) and baseline MM (kg) (r=−0.116, P=0.004). Change in BFM (%) was inversely correlated with the baseline BFM (%) (r=−0.262, P<0.001) and positively correlated with baseline MM (kg) (r=0.081, P<0.001). Change in MM (kg) correlated positively with baseline WHR (r=0.120, P=0.003) and BFM (%) (r=0.156, P<0.001).

Conclusion: PoZdro! programme resulted in significant reduction of BMI and WHR and improvement in body composition. Participants with higher baseline BMI and MM (kg) achieved greater decrease in BMI. Changes in body composition were greater in more obese adolescents.