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57th Annual ESPE

Athens, Greece
27 Sep 2018 - 29 Sep 2018

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ESPE 2018 57th European Society for Paediatric Endocrinology Annual Meeting 27-29 September 2018 Athens, Greece

Poster Presentations

Fetal, Neonatal Endocrinology and Metabolism P1

hrp0089p1-p135 | Fetal, Neonatal Endocrinology and Metabolism P1 | ESPE2018

Cardiac and Vascular Assessments in Small- vs Appropriate-for-Gestational-Age Infants at Ages 1 and 2 Years

Garcia-Beltran Cristina , Sebastiani Giorgia , Pie Stella , Guerra Alberto , Lopez-Bermejo Abel , de Zegher Francis , Roses Ferran , Ibanez Lourdes

Background: Children born small-for-gestational age (SGA), especially those who experience spontaneous postnatal catch-up growth, are at increased risk for developing insulin resistance, central adiposity and cardiovascular abnormalities later in life. By age 3-6 years, SGA children have a broader aortic and carotid intima media thickness (aIMT and cIMT) which are markers of preclinical atherosclerosis.Objective: To assess longitudinally – at age 12...

hrp0089p1-p136 | Fetal, Neonatal Endocrinology and Metabolism P1 | ESPE2018

Bone Maturation as a Predictive Factor of Catch-up Growth During the First Year of Life in Born Small for Gestational Age Infants: A Prospective Study

Pepe Giorgia , Calafiore Mariarosa , Valenzise Mariella , Morabito Letteria , De Luca Filippo , Wasniewska Malgorzata

Background: About 85–90% of children born small for gestational age (SGA) experience a catch-up growth that occurs mostly during the first year of life and results in a full stature recovery by the age of 2. The remaining 10–15% do not undergo compensatory growth, achieving - if untreated - an adult height approximately 20 cm below their peers.Objective: The aim of this prospective one-center study was to investigate the relation between bone m...

hrp0089p1-p137 | Fetal, Neonatal Endocrinology and Metabolism P1 | ESPE2018

Neonatal Screening Tests in Premature Newborns in Southern Brasil

Furtado Ivy Hulbert Falcao , Kraemer Gabriela Carvalho , de Lima Marcella Rabassi , Domingos Mousseline Torquato , Pereira Rosana Marques , Cat Monica Nunes Lima , De Lacerda Luiz , da Silva Regina Paula Guimaraes Vieira Cavalcante , Sarquis Ana Lucia Figueiredo , Nesi-Franca Suzana

Neonatal screening tests are used for the screening of genetic, endocrine and metabolic diseases. Preterm newborns have a higher false-positive and false-negative results in neonatal screening. The objective of this study was to estimate the prevalence of false-positive and false-negative results in the neonatal screening tests for phenylketonuria, congenital hypothyroidism, biotinidase deficiency and congenital adrenal hyperplasia (CAH) in preterm newborns in Curitiba, to ana...

hrp0089p1-p138 | Fetal, Neonatal Endocrinology and Metabolism P1 | ESPE2018

Measurement of Estradiol and Testosterone in Umbilical Cord Blood by Gas Chromatography-Tandem Mass Spectrometry (GC-MS/MS); Comparisons with Radioimmunoassay (RIA)

Allvin Kerstin , Dahlgren Jovanna , Andersson Mats X , Ankarberg-Lindgren Carina

Background: We have previously shown radioimmunoassay (RIA) and gas chromatography-tandem mass spectrometry (GC-MS/MS) to be comparable when analyzing estradiol and testosterone concentrations in prepubertal and pubertal children. However, the reliability for steroid hormone determination with RIA in umbilical cord blood is not known. In general, older studies using RIA show higher values of testosterone, than more recent ones using MS/MS.Patients and me...

hrp0089p1-p139 | Fetal, Neonatal Endocrinology and Metabolism P1 | ESPE2018

Transient Neonatal Iatrogenic Hypothyroidism due to Iodinated Contrast

Harenstam Ulrika , Hafstrom Ola , Reims Annika

Introduction: Iodine is necessary for thyroid hormone synthesis, but when exposed to large quantities, iodine may have an inhibitory effect on hormone synthesis leading to hypothyroidism, known as the Wolff-Chaikoff effect. Newborns may be exposed to iodine through various events in early life. In 2012 three index cases with suspected iatrogenic hypothyroidism due to iodinated contrast exposure were discovered at the Neonatal department, The Queen Silvia Children’s Hospit...

hrp0089p1-p140 | Fetal, Neonatal Endocrinology and Metabolism P1 | ESPE2018

Sexual Dimorphism of IGF1 and IGF2 Expression in the Neonatal Rat Brain

Guerra-Cantero Santiago , Torrecilla Marta , Diaz Francisca , Argente Jesus , Chowen Julie

Insulin-like growth factor (IGF) 2 plays a fundamental role in prenatal growth and development. The IGF2 gene is imprinted, with the paternally inherited copy being active and the maternal copy being silenced in most tissues. During development, the expression of IGF2 is sexually dimorphic in some tissues and this is thought to be involved in the development of some sexually dimorphic features. For example, IGF2 expression is reported to be higher in the male brain co...