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57th Annual ESPE

Athens, Greece
27 Sep 2018 - 29 Sep 2018

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ESPE 2018 57th European Society for Paediatric Endocrinology Annual Meeting 27-29 September 2018 Athens, Greece

Working Groups

ESPE Paediatric and Adolescent Gynaecology Working Group (PAG)

hrp0089wg5.3 | ESPE Paediatric and Adolescent Gynaecology Working Group (PAG) | ESPE2018

Influence of Adiposity as a Determinant of the Age at Pubjeanertal Onset

Biro Frank

Multiple studies have examined the relationship between BMI and timing of the onset of puberty. The more salient measure of this relationship may be adiposity, which can be represented by fat mass, BMI z-score, or waist-to-height ratio. The relationship of greater BMI or adiposity to earlier pubertal onset in girls is generally consistent, and several mechanisms have been proposed. These potential mechanisms include impact of adiposity on leptin concentrations, altere...

hrp0089wg5.4 | ESPE Paediatric and Adolescent Gynaecology Working Group (PAG) | ESPE2018

Endocrine-Metabolic Outcome of Women with a History of Sexual Precocity

de Vries Liat

Central precocious puberty (CPP) may have endocrine and metabolic implications in adulthood. Long-term effects may be associated with the underlying neuroendocrine dysfunction leading to CPP, the GnRH analogue (GnRHa) therapy, or both. Data are conflicting on the long-term risk of polycystic ovarian syndrome in both treated and untreated women. Clinical hyperandrogenism has been more frequently reported in CPP women than in controls, with no significant difference between GnRH...