Objective: To investigate whether earlier mothers age at menarche is a risk factor of daughters early menarche, obesity, and short stature in young Korean female.
Research design and methods: We tested associations between mothers age at menarche, mothers adult body size and her daughters age at menarche, body size from the data of 6th Korea National Health and Nutrition Examination Survey (KNHANES VI) (20132015). We analyzed 999 pairs of mothers and daughters aged 1530 years who had menarche age and anthropometrics data.
Results: In the mothers, earlier menarche was not associated with short adult height or obesity. In contrast, in her daughter, earlier mothers menarche predicted shorter height and greater BMI. Daughter of earlier mothers menarche had a higher prevalence of short stature (<152 cm) than those of later menarche. The odds ratio (OR) of a short stature in daughter of earlier mothers menarche was 3.61 (95% CI, 1.906.88). In multivariate regression, the OR of a short stature remained 3.61 (95% CI, 1.906.88) after adjusting for age, mothers height, and household income.
Conclusions: Earlier age at menarche of mother increased the risk of early menarche and short stature of her daughter in young Korean female. Thus, knowledge of mothers menarche age is important in identifying female at risk for short stature.
27 - 29 Sep 2018
European Society for Paediatric Endocrinology