ESPE Abstracts (2018) 89 P-P3-048

Comparison of Serum 25-Hydroxy Vitamin D Levels among Children & Adolescence with Attention Deficit Hyperactivity Disorder and Healthy Lranian People

Heshmat Moayeri

Imam Khomeini Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of Iran

Background: Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent chronic behavioral disorder among children. No definite pathology is yet defined for this disorder and findings are in favor of multifactorial hypothesis.

Aims: This study was performed with the aim of determining the association between vitamin D serum levels and ADHD among 6-14 year-old children referring to Imam Khomeini Hospital Complex during 2014–2015 in Tehran, Iran.

Measurements & methods: This case-control study was performed on 50 healthy and 50 ADHD children. Data was collected in a researcher-made questionnaire. 25-Hydroxy vitamin D levels were measured and documented. Data was analyzed using Chi-square test, independent T-test and Regression by SPSS 19 software.

Results: Mean 25-Hydroxy vitamin D level was 16.57±9.09 ng/ml among ADHD patients and 22.24±12.76 among healthy children. Mean 25-Hydroxy vitamin D level was significantly lower among the case group compared to the control group (P=0.012). Severe Vitamin D deficiency was significantly more prevalent among the case group (P=0.0001). Adequate 25-Hydroxy vitamin D level was significantly more prevalent among the control group (P=0.002)

Conclusion: Hypovitaminosis D is more prevalent among Iranian ADHD children compared to healthy ones. It seems that Hypovitaminosis D is associated with ADHD symptoms as an independent background variable.

Keywords: Vitamin D Deficiency, Attention Deficit Hyperactivity Disorder, Children & adolesence

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