ESPE Abstracts (2018) 89 P-P3-281

Basal Metabolic Rate as Moderator of Inflammation in PCOS

Styliani Geronikoloua,b, Dennis Cokkinosb & Flora Bacopouloua

aFirst Department of Paedaitrics, National and Kapodistrian University of Athens Med School, Aghia Sophia Hospital, Athens, Greece; bBiomedical Research Foundation of the Academy of Athens, Athens, Greece

This prospective population study focuses on metabolic differences between adolescent patients with polycystic ovary syndrome (PCOS) and age/BMI matched non-PCOS controls recruited by the Centre for Adolescent Medicine and UNESCO Chair on Adolescent Health Care of the First Department of Paediatrics, at the ‘Aghia Sophia’ Children’s Hospital, in Athens, Greece. Bioimpendance is an established non-interventional method for the determination of the body composition and several metabolic parameters in health and disease investigations. The markers of metabolism chosen are: abdominal adipose tissue (AAT), basal metabolic rate (BMR), extra cellular water to body cell mass ratio (ECW/BCM). Finally, phase angle (PhA) was chosen as marker of tissue inflammation. No differences in metabolic markers were shown. Yet, a strong correlation between the BMR and PhA in adolescents with PCOS was observed (P=0.0.17); the correlation is suggested to be specific for the syndrome.

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