ESPE Abstracts

ESPE Abstracts

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58th Annual ESPE (ESPE 2019)

Vienna, Austria
19 Sept 2019 - 21 Sept 2019

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The theme of this year’s meeting is Variety and Variation in Paediatric Endocrinology. Join us in Vienna to explore the diversity we encounter in our discipline and the care that we have to exercise when using the term “normality”. Whilst gaining an update on the latest treatments, clinical best practice and cutting edge research in the field of paediatric endocrinology.

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Development of Testicular Organoids to Understand Disorders of Sex Development

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Partial CRISPR/Cas9 IL1R1 & IFNGR1 Knock-Down Improves ß-Cell Survival and Function Under Cytokine-Induced Inflammation

hrp0092ha1 | Development of Testicular Organoids to Understand Disorders of Sex Development | ESPE2019

Development of Testicular Organoids to Understand Disorders of Sex Development

Eozenou Caroline , McElreavey Ken , Bashamboo Anu

Disorders of sex development (DSD) constitute an array of rare disorders affecting the genito-urinary tract and the endocrine-reproductive system and are often identified in the newborn or adolescent. Gene mutations causing DSD are slowly being identified using high-throughput sequencing, but the interpretation of the data and ascribing causality to novel variants is challenging. This is because DSD mutations occur in multiple genes with each gene affecting a small number of i...

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ESPE Abstracts

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