hrp0092ha1 | Development of Testicular Organoids to Understand Disorders of Sex Development | ESPE2019
, McElreavey Ken
, Bashamboo Anu
Disorders of sex development (DSD) constitute an array of rare disorders affecting the genito-urinary tract and the endocrine-reproductive system and are often identified in the newborn or adolescent. Gene mutations causing DSD are slowly being identified using high-throughput sequencing, but the interpretation of the data and ascribing causality to novel variants is challenging. This is because DSD mutations occur in multiple genes with each gene affecting a small number of i...