ESPE Abstracts (2019) 92 MTE2

The Interpretation of Abnormal Thyroid Function in Tests in Children and Adolescents

Carla Moran


Beacon Hospital, Dublin, Ireland. Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom


Patients with discordant thyroid function tests (TFTs) are common clinical conundrums for the practising paediatric and adult endocrinologist. In order to avoid unnecessary investigation and treatment, a structured approach to the work up is required. During this session I will use a case based approach to review common causes of discordant TFTs, such as confounding physiological and pathophysiological factors, analytical errors, binding protein abnormalities and genetic causes. I will also provide a practical algorithm to the initial investigation and further work up of such patients.

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