Introduction: Prolactinoma is the most frequent pituitary tumor (40 %) in children and adolescents is more common in females, sporadic and benign. It is classified into microprolactinoma (< 1.0 cm) and macroprolactinoma (>1.0 cm). In girls it presents clinically as amenorrhea and galactorrhea and occasionally as increased intracranial pressure. Management consist of medications and surgery.
Objectives: To characterize patients seen at Pediatric Endocrinology Clinics from three Institution between july 2000 and November 2018.
Materials and Methods: Review of charts from patients with prolactinoma.
Results are presented in table 1. micro: microadenoma, Macro: macroadenoma *F:female.M:male, n/a does not apply
|Pacient||Age years||Sex||Galactorrhea||Amenorrhea||size||Prolactin. ng/ml||surgery||drugs|
Analysis: Ten patients, mean age 12.4±3.0 years, male 60%,40% female,60%debuted with galactorrhea,75% of women with amenorrhea,75% debuted with intracranial hypertension data 40% surgical management 60%had macroadenomas and 40% microadenomas, mean prolactin 470±271ng /ml.
Conclusions: We must suspect CNS tumors in patient with intracraneal hyppertension symtoms .Macroadenomas are more common in our pediatric population and as such surgery is the most common approach.
19 - 21 Sep 2019
European Society for Paediatric Endocrinology