Previous issue | Volume 94 | ESPE2021

59th Annual ESPE (ESPE 2021 Online)

Online,
22 Sep 2021 - 26 Sep 2021

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The 59th ESPE Annual Meeting will now be held online in September 2021.

ePoster Category 2

Adrenals and HPA Axis

Circadian rhythm of salivary cortisol and cortisone in school-aged children born very preterm and adequate for gestational age
1Pediatric Division, School of Medicine; Pontificia Universidad Católica, Santiago, Chile; 2Department of Clinical Laboratories, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile; 3Endocrinology Department, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile
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How do urine steroid metabolites of spot samples correlate with 24 hour urine specimens in children with congenital adrenal hyperplasia?
1Pediatric Endocrinology, Diabetology and Metabolism, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; 2Department for BioMedical Research, University of Bern, Bern, Switzerland; 3Department of Pediatrics, Division of Endocrinology, Erasmus MC-Sophia, University Medical Center, Rotterdam, Netherlands; 4Department of Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; 5Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, Athens, Greece; 6Division of Endocrinology and Metabolism, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece
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Endocrine-disrupting chemicals: an often-forgotten etiology of endocrinological disturbances
1Paediatric Endocrinology Unit, Hospital de Dona Estefânia – Central Lisbon University and Hospital Centre, Lisbon, Portugal; 2Paediatric Service, Leiria Hospital Centre, Leiria, Portugal
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Serum Sex Hormone Binding Globulin Levels, But Not 4-Hour Profile of 17-Oh Progesterone, Would Be Useful in Monitoring Children with Congenital Adrenal Hyperplasia
1Division of Pediatric Endocrinology, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey; 2Department of Biochemistry, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey
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Glucocorticoid side-effects in Duchenne Muscular Dystrophy: Systematic review of side effects in published literature and a survey of the concerns of the patient community
1School of Medicine, University of Glasgow, Glasgow, United Kingdom; 2School of Medicine, University of Glasgow, Department of Paediatric Endocrinology, Royal Hospital for Children, Glasgow, Glasgow, United Kingdom
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Single centre experience of Hydrocortisone Granules (Alkindi) in children under 6 years of age with Adrenal Insufficiency
Department of Paediatric Endocrinology, Great North Children’s Hospital, Newcastle upon Tyne, United Kingdom
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Emotion regulation in congenital adrenal hyperplasia
1Karolinska Institute, Stockholm, Sweden; 2Danish Technical University, Lyngby, Denmark
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High-dose steroids in the management of Paediatric Multisystem Inflammatory Syndrome Temporally associated with SARS-CoV-2 (PIMS-TS): Considering the hypothalamic-pituitary-adrenal axis
1Department of Paediatric Endocrinology and Diabetes, London, United Kingdom; 2Paediatric Intensive Care Unit, Great Ormond Street Hospital, London, United Kingdom
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Variability of advice and education for steroid sick day dosing in Duchenne Muscular Dystrophy and the impact of the COVID-19 pandemic: Results of a UK wide patient survey
1Duchenne UK, United Kingdom, United Kingdom; 2Department of Endocrinology and Diabetes, Evelina Children’s Hospital, London, United Kingdom; 3Department of Paediatric Endocrinology, Great Ormond Street Hospital for Children, London, United Kingdom; 4Dubowitz Neuromuscular Centre, Great Ormond Street Hospital for Children, London, United Kingdom; 5Department of Paediatric Endocrinology, Leeds Teaching Hospital NHS Trust, Leeds, United Kingdom; 6John Walton Muscular Dystrophy Research Centre, Newcastle, United Kingdom; 7Newcastle University Translational and Clinical Research Institute, Newcastle, United Kingdom; 8Department of Paediatric Endocrinology, Royal Hospital for Children Glasgow, Glasgow, United Kingdom; 9School of Medicine, University of Glasgow, Glasgow, United Kingdom
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Clinical characteristics of cytochrome P450 oxidoreductase deficiency: a nationwide survey in Japan
1Department of Pediatrics and Child Health, Kurume University School of Medicine, Fukuoka, Japan; 2Department of Pediatrics, Keio University, Tokyo, Japan; 3Department of Pediatrics, Hiroshima University, Hiroshima, Japan; 4Department of Pediatrics, Shimane University, Izumo, Japan; 5Department of Pediatrics, Tokyo Medical and Dental University, Tokyo, Japan; 6Department of Pediatrics, Niigata University Medical & Dental Hospital, Niigata, Japan; 7Department of Pediatrics, Hokkaido University, Sapporo, Japan; 8Department of Pediatrics, Osaka City University, Osaka, Japan; 9Department of Pediatrics, Yamagata University, Yamagata, Japan; 10Department of Pediatrics, Tohoku University, Sendai, Japan; 11Department of Pediatrics, Teikyo University Chiba Medical Center, Ichihara, Japan; 12Department of Pediatrics, Jichi Medical University, Shimotsuke, Japan
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Rare Presentation of Adrenal Insufficiency in an Infant with Holocarboxylase Synthetase Deficiency
1College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman; 2Paediatric Intensive Care Unit, Sultan Qaboos University Hospital, Muscat, Oman; 3Paediatric Endocrine Unit, Sultan Qaboos University Hospital, Muscat, Oman; 4Dermatology Department, Sultan Qaboos University Hospital, Muscat, Oman; 5Genetics Department, Sultan Qaboos University Hospital, Muscat, Oman; 6University of Manchester, Manchester, United Kingdom
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Utilisation Of The I-CAH Registry As A Tool For Facilitating Health Quality Improvement Strategies- Results Of An International Survey Of Specialist Centres
1Royal Hospital for Children, Glasgow, United Kingdom; 2University of Glasgow, Glasgow, United Kingdom; 3The Royal Children’s Hospital & Murdoch Children’s Research Institute, Melbourne, Australia; 4University Hospital Southampton, Southampton, United Kingdom
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Clinical and hormonal evolution of aldosterone synthase deficiency: Is complete remission possible?
1Marmara University, Istanbul, Turkey; 2Umraniye Research and Training Hospital, Istanbul, Turkey; 3Gazi Yasargil Education and Research Hospital, Istanbul, Turkey; 4Pamukkale University, Denizli, Turkey; 5Ondokuz Mayis University, Samsun, Turkey; 6Erzurum Education and Research Hospital, Erzurum, Turkey; 7Gazi University, Ankara, Turkey; 8Haseki Training and Research Hospital, Istanbul, Turkey; 9Dr. Behcet Uz Children’s Hospital, Istanbul, Turkey; 10Koç University Hospital, Istanbul, Turkey; 11National Hematology and Transfusiology Center, Baku, Azerbaijan
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Rapid clearance of hydrocortisone as a cause of poor control of CAH detected by 24-hour profiling of hydrocortisone concentrations.
1Department of Paediatrics, Royal Free NHS Trust, Barnet Hospital, London, United Kingdom; 2MRC Epidemiology Unit & Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom; 3Department of Paediatrics, University College London Hospitals, London, United Kingdom; 4Centre for Endocrinology, William Harvey Research Institute, Barts and the London School Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; 5Department of Paediatric Endocrinology, Barts Health NHS Trust, Royal London Children’s Hospital, London, United Kingdom
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Genetic analysis of paediatric primary adrenal insufficiency of unknown aetiology over 25 years
1Genetics & Genomic Medicine Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, United Kingdom; 2Centre for Endocrinology, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom; 3Children’s Hospital, Universitätsklinikum Dresden, Technische Universität Dresden, Dresden, Germany; 4The Royal London Childrens Hospital, Barts Health NHS Trust, London, United Kingdom; 5Department of Paediatric Endocrinology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; 6Department of Child Health, King’s College Hospital NHS Foundation Trust, London, United Kingdom; 7Newcastle University and Great North Children’s Hospital, Newcastle upon Tyne, United Kingdom; 8Bristol Royal Hospital for Children, University Hospitals Bristol, NHS Foundation Trust, Bristol, United Kingdom; 9Faculty of Medicine, University of Southampton, Southampton, United Kingdom; 10Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom; 11Department of Paediatrics, University College London Hospitals, London, United Kingdom; 12Paediatric Endocrinology, Evelina London Children’s Hospital, Guy’s and St Thomas’ NHS Trust, London, United Kingdom; 13Academic Unit of Child Health, Department of Oncology and Metabolism, University of Sheffield, Sheffield Children’s Hospital, Sheffield, United Kingdom; 14Department of Paediatric Endocrinology, Royal Hospital for Children, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom; 15Northern Genetics Service, International Centre for Life, Newcastle, United Kingdom; 16Developmental Biology & Medicine, Faculty of Biology, Medicine & Health, University of Manchester, and the Royal Manchester Children’s Hospital, Manchester University Hospital NHS Foundation Trust, Manchester, United Kingdom; 17Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, United Kingdom
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Panhypopituitarism after treatment procedures in pituitary-hypothalamic area - a single center experience
1UMHAT “St. Marina”, First Paediatric Clinic, Varna, Bulgaria; 2Medical University, Department of Paediatrics, Varna, Bulgaria; 3UMAHT "G.Stranski", Pleven, Bulgaria; 4Medical University, Department of Paediatrics, Pleven, Bulgaria; 5UMHAT "St. Marina", Department of Neurosurgery, Varna, Bulgaria; 6Medical University, Department of Neurosurgery, Varna, Bulgaria
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The reliability of Salivary Cortisol compared to Serum Cortisol for diagnosing adrenal insufficiency in the gold standard ACTH stimulation test in children
1Division of Endocrinology, Department of Pediatrics, Erasmus MC-Sophia Children’s Hospital, University Medical Center, Rotterdam, Netherlands; 2Post-graduate School of Pediatrics, Department of Medical and Surgical Sciences for Mother, Children and Adults, University of Modena and Reggio Emilia, Modena, Italy; 3Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, Netherlands
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Prevalence of adrenal insufficiency (AI) requiring treatment with hydrocortisone in children tested with the LDSST
1Alder Hey Children’s Hospital, Liverpool, United Kingdom; 2University of Liverpool, Liverpool, United Kingdom; 3University of Lancaster, Lancaster, United Kingdom
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The incidence and presentation of congenital adrenal hyperplasia in an unscreened population
1Department of Endocrinology, CHI at Temple Street, Dublin, Ireland; 2School of Medicine, University College Dublin, Dublin, Ireland; 3Department of Paediatrics and Child Health, University College Cork, Cork, Ireland; 4Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA; 5Division of Endocrinology and Diabetes, The Children’s Hospital of Philadelphia, Philadelphia, USA; 6Department of Clinical Biochemistry, CHI at Temple Street, Dublin, Ireland
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Genotypic Sex and Severity of the Disease Determine the Time of Clinical Presentation in Steroid 17[alpha]-Hydroxylase/17,20-Lyase Deficiency
1Erzurum Regional Research and Training Hospital, Department of Pediatric Endocrinology and Diabetes, Erzurum, Turkey; 2Erzurum Regional Research and Training Hospital, Department of Internal Medicine, Division of Endocrinology and Metabolism, Erzurum, Turkey; 3Erzurum Regional Research and Training Hospital, Department of Medical Genetics, Erzurum, Turkey; 4Marmara University, School of Medicine, Department of Paediatric Endocrinology and Diabetes, İstanbul, Turkey
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High doses op’-DDD cause metrorragia in young girls
1Department of Pediatric Endocrinology, AP-HP University Paris-Saclay, Hospital Bicêtre, Le Kremlin-Bicêtre, France; 2CESP, INSERM, Cancer Radiation Team, Gustave Roussy Institute, Villejuif, France
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An Adolescent Case With Adrenoleukodystrophy Diagnosed After Detection Of Leydig Cell Dysfunction
1University of Health Sciences Turkey, Dr. Sami Ulus Obtetrics And Gynecology, Children’s Health and Disease Training And Research Hospital, Department of Pediatric Endocrinology, Ankara, Turkey; 2University of Health Sciences Turkey, Dr. Sami Ulus Obtetrics And Gynecology, Children’s Health and Disease Training And Research Hospital, Department of Pediatric Metabolism, Ankara, Turkey; 3University of Health Sciences Turkey, Dr. Sami Ulus Obtetrics And Gynecology, Children’s Health and Disease Training And Research Hospital, Department of Pediatric Neurology, Ankara, Turkey; 4University of Health Sciences Turkey, Dr. Sami Ulus Obtetrics And Gynecology, Children’s Health and Disease Training And Research Hospital, Department of Pediatric Radiology, Ankara, Turkey; 5University of Health Sciences Turkey, Dr. Sami Ulus Obtetrics And Gynecology, Children’s Health and Disease Training And Research Hospital, Department of Medical Genetics, Ankara, Turkey
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Fludrocortisone is the salvage treatment in cases with calcineurin inhibitor related hyperkalemia
1Hacettepe University Pediatric Endocrinology, Ankara, Turkey; 2Hacettepe University Pediatric Nephrology, Ankara, Turkey; 3Hacettepe University Pediatric Hematology, Ankara, Turkey
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Development of a novel weight-based steroid emergency plan for patients with Duchenne Muscular Dystrophy
1Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom; 2Genetics and Genomic Medicine Programme, London, United Kingdom
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Congenital Adrenal Hyperplasia caused by homozygous pathogenic variant in the HSD3B2 gene.
1First Department of Paediatrics, Medical School, NKUA, Athens, Greece; 2"Agia Sofia" Children’s Hospital, Athens, Greece; 3First Pediatric Department, School of Medicine, Faculty of Medical Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece; 4“Ippokratio” General Hospital, Thessaloniki, Greece; 5First Department of Paediatrics, Medical School NKUA, Athens, Greece
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Congenital Adrenal Hyperplasia with a CYP21A2 deletion overlapping Tenascin-X gene
1Departamento de Endocrinologia, Hospital das Forças Armadas (HFAR), Lisbon, Portugal; 2Unidade de Endocrinologia Pediátrica, Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central (CHULC), Lisbon, Portugal; 3Unidade de Reumatologia Pediátrica, Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central (CHULC), Lisbon, Portugal; 4Departamento de Genética Humana, Instituto Nacional de Saúde Dr Ricardo Jorge, Lisbon, Portugal
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Maternal primary adrenal cortex insufficiency during pregnancy: Spotlight on the Fetus and the Neonate. A systematic review and meta-analysis.
1Endocrine Unit, “Aretaieion” Hospital, National and Kapodistrian University of Athens, Faculty of Medicine, Athens, Greece; 2Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, ‘Aghia Sophia’ Children’s Hospital, Athens, Greece; 32nd Department of Obstetrics and Gynecology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece; 4Second Department of Obstetrics and Gynecology, “Aretaieion” Hospital, National and Kapodistrian University of Athens, Athens, Greece
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Assessment of blood pressure and carotid intima media thickness (CIMT) in children with primary adrenal insufficiency
1Alder Hey Children’s Hospital, Liverpool, United Kingdom; 2University of Liverpool, Liverpool, United Kingdom; 3Liverpool Centre for Cardiovascular Science, Liverpool, United Kingdom
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Challenging in diagnosis and treatment of Cushing Disease in a 12 years old boy
Unit of Pediatric Endocrinology, Department of Pediatrics, University Hospital Centre “Mother Teresa”, Albania, Tirana, Albania
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Congenital Adrenal Hyperplasia caused by compound heterozygosity of two novel CYP11B1gene variants.
1National and Kapodistrian University of Athens, Athens, Greece; 2“Agia Sophia” Children’s Hospital, Athens, Greece
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Addison’s disease: Delay in diagnosis in a girl with longstanding symptoms
1Dept. of Endocrinology-Growth and Development, Children’s Hospital P. & A. Kyriakou, Athens, Athens, Greece; 2Department of Biochemistry, P. & A. Kyriakou” Children’s Hospital, Athens, Greece
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Clinical spectrum of congenital adrenal hyperplasia due to 3 beta hydroxysteroid dehydrogenase deficiency; A case series
1Children’s Hospital & Institute of Child Health, Lahore, Pakistan; 2Hameed Latif Hospital, Lahore, Pakistan
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Retrospective Evaluation of Cases Diagnosed with Classical Congenital Adrenal Hyperplasia Due to 21 Hydroxylase Deficiency
1Dr. Sami Ulus Children Hospital, Pediatrics, Ankara, Turkey; 2Dr. Sami Ulus Children Hospital, Pediatric Endocrinology, Ankara, Turkey
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Corticotropin-independent Cushing’s Syndrome in toddlerhood: a challenging diagnosis and treatment
1Paediatric Endocrinology Unit - Hospital Dona Estefânia, CHULC, Lisbon, Portugal; 2Nuclear Medicine-Radiopharmacology Department, Champalimaud Foundation, Lisbon, Portugal
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A case of adrenal insufficiency during the course of multisystem inflammatory syndrome in children (MIS-C)
1Pediatric Endocrinolgy and Diabetes, Kocaeli University, Kocaeli, Turkey; 2Department of Academic Writing, Kocaeli University, Kocaeli, Turkey; 3Pediatric Nephrology, Kocaeli University, Kocaeli, Turkey; 4Pediatrics, Kocaeli University, Kocaeli, Turkey
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A Rare Coexistence of two autosomal recessive conditions: Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency (CYP21A2 mutation) with Beta Thalassemia Major
1Department of Paediatric Endocrinology and Diabetes, The Children’s Hospital & The Institute of Child Health, Lahore, Pakistan; 2Department of Pediatric Endocrinology, Hameed Latif Hospital, Lahore, Pakistan; 3Department of Paediatric Gastroenterology and Hepatology, The Children’s Hospital & The Institute of Child Health, Lahore, Pakistan
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X-linked Adrenoleukodystrophy in south of Tunisia
1Pediatrics Department, Hedi Chaker University Hospital, Sfax, Tunisia; 2Faculty of Medicine of Sfax, Sfax University, Sfax, Tunisia; 3Genetic Department, Hedi Chaker University Hospital, Sfax, Tunisia
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Clinical, biological and genetic aspects of congenital adrenal hyperplasia in children at the Central Army Hospital in Algiers
1Endocrinology Department, Central Army Hospital, Algiers, Algeria; 2Endocrine Pathologies and Cystic Fibrosis Medical, Molecular and Hormonal Unit, Department of Biochemistry and Molecular Biology, Hospices Civils de Lyon, Lyon, France
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Coexistence of Adrenal Insufficiency and Hypergonadotropic Hypogonadism: P450scc Deficiency
1Department of Pediatric Endocrinology, Health Sciences University, Dr Sami Ulus Obstetrics and Gynecology, Child Health and Diseases Training and Research Hospital, Ankara, Turkey; 2Department of Pediatric Endocrinology and Diabetes, Marmara University School of Medicine, İstanbul, Turkey
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First case in Lebanon of homozygous mutation in CYP 11B2 leading to isolated aldosterone deficiency.
1LAU Gilbert and Rose-Marie Chagoury School of Medicine and LAU Medical Center-Rizk Hospital, Beirut, Lebanon; 2University of Massachusetts Medical School, Worcester, MA, USA
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Adrenal insufficiency masquerading as biliary atresia in an infant
Sirimavo Bandaranayke Specialized Children’s Hospital, Kandy, Sri Lanka
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Mutation of NROB1 and Double mutants in cis of CYP21A2 gene in a Chinese boy with primary adrenal insufficiency
1The First Affiliated Hospital of Sun Yat Sen University, Guangzhou, China; 2Rujiang, ZHENG, China
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Twin infants with salt-wasting: double the trouble
1Nicklaus Children’s Hospital, Miami, USA; 2Nicklaus Children’s Hospital Department of Endocrinology, Miami, USA
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Effect of treatment of double precocious puberty in a 9-year-old girl- case report
Department of Pediatrics, Endocrinology and Diabetology with the Cardiology Division, Medical University in Bialystok, Bialystok, Poland
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Classical Congenital adrenal hyperplasia: about 7 cases
Department of Endocrinology-Diabetology and Nutrition, Mohammed VI University Hospital, OUJDA, Morocco
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