ESPE Abstracts (2021) 94 P2-167

ESPE2021 ePoster Category 2 Diabetes and insulin (72 abstracts)

Blood level of Vitamin D and metabolic control of type 1 diabetes mellitus

Maryam Razzaghy-Azar 1,2 , Mona Nourbakhsh 3 , Mitra Nourbakhsh 4 , Erfan Abdiaei 5 & Hossein Abdiaei 5


1Hazrat Aliasghar Children’s Hospital Iran University of Medical Sciences, Tehran, Iran; 2Metabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran; 3Hazrat Aliasghar Children’s Hospital, Iran University of Medical Sciences, Tehran, Iran; 4Department of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran; 5Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran


Background: There are some studies about vitamin D level and type 1 or type 2 diabetes mellitus (DM). Its effect on metabolic control of patients with type 1 DM is the subject of this study.

Patients and Method: In 339 patients with type 1 DM, 192 cases (99 males, 93 females) randomly enrolled in the study. The age of males was 9 ± 4.4 yr and age of females was 8.3±4.3 yr. Their HbA1C and 25(OH) D3 were measured by HPLC method. Vitamin D level was divided into group 1: ≤ 10 ng/ml, group 2: 11 – 20 ng/ml, group 3: 21 – 30 ng/ml, group4 : > 30 ng/ml. HbA1C level was compared in different vitamin D groups.

Results: Mean±SD of HbA1C was 10.2±2.3 in group 1 that was significantly higher than group 3 (8.2±1.6) (P value: 0.001) and group 4 (8.8±2.4)(P = 0.024). It was 9.7±2.3 in group 2 that was significantly higher than group 3 (P: 0.003) and group 4 (0.045). There was no significant difference between group 1 and 2 and also between group 3 and 4.

Conclusion: Vitamin D level more than 20 is accompanied by better metabolic control of type 1 diabetes mellitus.

Volume 94

59th Annual ESPE (ESPE 2021 Online)

Online,
22 Sep 2021 - 26 Sep 2021

European Society for Paediatric Endocrinology 

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