ESPE Abstracts (2021) 94 P2-166

ESPE2021 ePoster Category 2 Diabetes and insulin (72 abstracts)

How Does Continuous Glucose Monitoring Systems Effect Metabolic Control In Type 1 Diabetes: Single Center Experience

Emrullah Arslan , Eren ER , Gunay Demir , Hafize Isiklar , Yasemin Atik Altinok , Samim Ozen , Sukran Darcan & Damla Goksen


Ege Faculty of Medicine, Department of Pediatric Endocrinology and Diabetes, Izmir, Turkey

Introduction: Continuous Glucose Monitoring System (CGMS) takes place increasingly in the daily routines of diabetic patients. It has been shown that metabolic control improves when CGMS is used consistently. We aimed to show the effect of CGMS in patients using MDI therapy

Materials - Methods: All patients using multiple-dose insulin therapy at our center and continued their regular follow-up and using CGMS for at least three months were screened through their files. Eight of the 70 patients were excluded from the study because they switched to insulin pump therapy, 17 patients were on their honeymoon period, one patient was diagnosed with MODY, three patients were diagnosed with type 2 diabetes who only used metformin, and six patients were using for less than three months, so 35 patients were included in the study. Anthropemetric measurements, insulin doses, HbA1c and sensor data of all cases were compared with the data of the last two weeks when they were actively using the sensor.

Results: It was shown that patients’ weight, weight SDS increased with the use of sensors, and a statistically significant decrease was achieved in HbA1C (Table 1). In addition, the increase in the duration of sensor use correlated with a decrease in glucose variability, an increase in TIR, and a decrease in TAR (Table 2). While a decrease of 8.6% is observed in TIR with the use was less than 15 months, the benefit of using the sensor > 15 months is clearly seen, and a 7.2% increase is observed in TIR (p: 0.016). However, a significant decrease in TBR was not detected. After using the sensor, the awareness of the patients about hyperglycemia raised, they intervened more to reduce their blood glucose values and probably they consume more food because they can monitor blood glucose levels more closely.

Table 1. Comparison of the first 2 weeks after sensor insertion and the last 2 weeks of sensor use
Weight (kg)44,651,7<0,001
Weight SDS0,220,470,034
BMI SDS-0,030,260,072
Table 2. Correlation with Sensor Lifetime and Glycemic Control Parameters
Pearson Correlation Coefficientp
Glucose Variability (CV)0,5990,001
Time Between 70-180 mg/dl-0,410,014
Time Between 180-250 mg/dl0,3730,027
>250 mg/dl elapsed time0,3450,046

Volume 94

59th Annual ESPE (ESPE 2021 Online)

22 Sep 2021 - 26 Sep 2021

European Society for Paediatric Endocrinology 

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