ESPE Abstracts (2021) 94 P2-204

ESPE2021 ePoster Category 2 Fat, metabolism and obesity (59 abstracts)

Changes in objectively measured physical activity after 2-year lifestyle intervention in pediatric patients with abdominal obesity

Ana Ojeda-Rodríguez 1,2 , Lydia Morell-Azanza 1,2 , Jose Luis León 3 , María Macías 3 , María Chueca 2,4 , Amelia Marti 1,2 & María Cristina Azcona-Sanjulian 2,3

1University of Navarra, Pamplona, Spain; 2Institute of Research of Navarra, Pamplona, Spain; 3Clínica Universidad de Navarra, Pamplona, Spain; 4Complejo Hospitalario de Navarra, Pamplona, Spain

Introduction: it has been widely demonstrated that high physical activity (PA) levels prevent obesity development. The practice of moderate, regular PA reduces abdominal obesity, hypertension, insulin resistance, dyslipidemia and improves risk factors for obesity-related comorbidities (e.g. diabetes or cardiovascular diseases) independently of weight loss. However, in the childhood population, where sedentary behavior has increased in recent decades, few studies have assessed the effect of lifestyle interventions on changes in PA, measured by accelerometry in pediatric patients with abdominal obesity.

Methods: one hundred and two children and adolescents with abdominal obesity (7-16 years old) were enrolled in a lifestyle intervention program for two years. Participants were encouraged to accumulate extra 200 min/week of PA. PA was assessed by accelerometry. Available data of objectively measured PA was obtained from 38 participants at the end of intervention.

Results: participants (mean age 11 years; 61% female) achieved a significant reduction in anthropometric (percentage of fat mass -3.99±5.76; P < 0.001) and biochemical parameters (total cholesterol -15.12±21.41, P < 0.001; LDL-cholesterol -12.27±16.18, P < 0.001; triglycerides -26.81±39.63; leptin -6.95±14.03, P = 0.023) after the 2-year lifestyle intervention. In addition, a significant decrease in light PA levels (-87 min/day, P < 0.001) was observed. In multiple regression analysis changes in light PA levels were positively associated with changes in leptin levels (R2= 0.321, P = 0.012).

Conclusion: participants significantly improved anthropometric and biochemical parameters. In addition, favorable changes in PA levels could affect leptin levels after 2-year lifestyle intervention in pediatric patients with abdominal obesity.

Volume 94

59th Annual ESPE (ESPE 2021 Online)

22 Sep 2021 - 26 Sep 2021

European Society for Paediatric Endocrinology 

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