ESPE Abstracts (2021) 94 P2-452

ESPE2021 ePoster Category 2 Thyroid (46 abstracts)

Complications after pediatric thyroidectomy: lymph node dissection is a risk factor for permanent hypocalcemia

Jesse J. van Rooijen 1 , A.S. Paul van Trotsenburg 1 , Nitash Zwaveling-Soonawala 1 , Els J.M. Nieveen van Dijkum 2 , Anton F. Engelsman 2 , Joep P.M. Derikx 3 & Christiaan F. Mooij 1


1Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands; 2Department of Surgery, Amsterdam University Medical Center, University of Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands; 3Department of Pediatric Surgery, Emma Children’s Hospital, Amsterdam University Medical Center, University of Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands


Background: Thyroidectomy is a definitive treatment option in some benign thyroid disorders and the definitive treatment option for thyroid cancer. As postoperative mortality is extremely rare data on postoperative complications and long-term health consequences are important.

Objective: To evaluate the frequencies of short- and long-term complications, and their risk factors in pediatric patients (0-18 years) who underwent a thyroidectomy in a tertiary children’s hospital.

Methods: A retrospective single center study was performed including all pediatric patients who underwent a thyroidectomy between January 2013 and February 2020.

Results: Forty-eight patients were included in this study (mean age 14.6 years, 37 females (77.1%)). Twenty-nine (60.0%) total thyroidectomies and 19 (40.0%) hemithyroidectomies were conducted. Twelve patients underwent a thyroidectomy because of thyroid carcinoma, thirty-six patients because of a benign thyroid disorder. After total thyroidectomy, rapidly resolved hypocalcemia was observed in three patients (10.3%), transient hypocalcemia in 10 patients (34.5%) and permanent hypocalcemia in six patients (20.7%). Permanent hypocalcemia was only seen in patients who underwent a thyroidectomy with additional lymph node dissection because of thyroid carcinoma (thyroid carcinoma: OR 43.73, 95% CI [2.11-904.95]; lymph node dissection: OR 76.14, 95% CI [3.49-458.98]). Transient and permanent recurrent laryngeal nerve injury was reported in four (8.3%) and one (2.1%) of all patients, respectively.

Conclusion: Permanent postoperative complications after thyroidectomy are rare in pediatric patients undergoing a thyroidectomy without lymph node dissection. However, in this age group permanent hypocalcemia occurs more frequently after thyroidectomy with additional lymph node dissection because of thyroid cancer. With respect to quality of life, especially of pediatric thyroid cancer patients, reducing this complication is an important goal.

Volume 94

59th Annual ESPE (ESPE 2021 Online)

Online,
22 Sep 2021 - 26 Sep 2021

European Society for Paediatric Endocrinology 

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